EVERYONE Will Get Finasteride Side-Effects Eventually

whatevr

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@Pigeon , congratulations. You've collected quite a bibliography of studies there.

I took Finasteride for 1 year, and other than ongoing gynecomastia while taking it I didn't feel that bad... until I quit.

Within a few weeks it became increasingly hard for me to think. I lost all creative drive (used to do 3D modeling and make music), libido was near nonexistent, orgasms pleasureless. My dick was very numb and had barely any sensation to touch, after a while I noticed structural abnormalities like skin discolorations, rubbery tissue and the erection quality was so poor as if some areas weren't getting blood flow at all.

Took me 2 years to connect the dots that this was from Finasteride usage, once I found a myriad of people online with the same symptoms. Of course I tried a vast array of supplements and herbs, to no avail, and only now, after doing steroid cycles with Proviron, followed by Tamoxifen & HCG PCT am I starting to feel normal and even reversing some of the damage that androgen deprivation caused to my dick.

It's a f*****g tragedy that we are still stuck with this drug as the #1 choice for hair loss, because even though people with outcomes like myself are probably in the minority, the fact that this can happen to someone from a drug that they take for their hair is unacceptable.

My hair now is almost as bad as before I ever took Propecia (NW3) and even though hair loss is still a concern to me, the price I paid for inhibiting 5-alpha reductase (4 years of my life living like a zombie) was absolutely not worth it. Either I will find another way or just go bald, because I sure as sh*t don't plan on putting my balls on the chopping block with hormonal treatments again.
 

-G-

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On a more serious note, I do not refute that people suffer with pills such as finasteride, what I am unable to reconcile is the amount of people taking it versus the amount of occurrences noted.

Sure, from a business standpoint, I would minimize the effects of the pill, but being out for 20+ years (If I am not mistaken), would I continue to risk my business? Again unless I am missing something.

Why even produce something that is possibly going to lead me liable?

Or

Are we men less likely speak up.
 

Charger

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On a more serious note, I do not refute that people suffer with pills such as finasteride, what I am unable to reconcile is the amount of people taking it versus the amount of occurrences noted.

Sure, from a business standpoint, I would minimize the effects of the pill, but being out for 20+ years (If I am not mistaken), would I continue to risk my business? Again unless I am missing something.

Why even produce something that is possibly going to lead me liable?

Or

Are we men less likely speak up.
Finasteride has a black box warning in some countries... and no one really 'owns' finasteride as far as I'm aware, there's multiple brands of it. Generic and so forth.

I think side effects are likely under reported outside of the internet. No one wants to admit they broke their dick because they wanted to keep their hair. When I got hit with finasteride side effects, I definitely felt shameful about it.

I also think there's a large group of (middle aged and older) people that are prescribed the drug and assume that the side effects are simply due to their age, especially if it was prescribed specifically for prostate issues.
 

-G-

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Finasteride has a black box warning in some countries... and no one really 'owns' finasteride as far as I'm aware, there's multiple brands of it. Generic and so forth.

I think side effects are likely under reported outside of the internet. No one wants to admit they broke their dick because they wanted to keep their hair. When I got hit with finasteride side effects, I definitely felt shameful about it.

I also think there's a large group of (middle aged and older) people that are prescribed the drug and assume that the side effects are simply due to their age.

That's fair that some think it could be age related.

Regardless of who "owns" or if it is generic, a company still makes it and would be liable no? IF so, why make it if the benefits did not out weigh the risks?
 

Charger

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That's fair that some think it could be age related.

Regardless of who "owns" or if it is generic, a company still makes it and would be liable no? IF so, why make it if the benefits did not out weigh the risks?

I mean it's an FDA approved drug, I don't think there's any reason why a company would be hesitant to produce it. It's an antiandrogen/5ARi, it does what it's supposed to do, lol.

Assuming a person goes through the proper avenues to get prescribed the drug by a qualified physician, they should be more than well aware of the potential side effects.
 

Charger

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Forgive my ignorance, do you mean a regimen involving PGD2 antagonists?

PGD2 Inhibitors, DKK1 inhibitors, PGE2 Promoters, WNT agonists, etc.
 

NaNaMaOn

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PGD2 Inhibitors, DKK1 inhibitors, PGE2 Promoters, WNT agonists, etc.

Interesting, I’m already using oral caster oil but I imagine that’s pretty small fry compared to other PGE2 promoters. Any sides from any of this stuff?
 

Charger

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Interesting, I’m already using oral caster oil but I imagine that’s pretty small fry compared to other PGE2 promoters. Any sides from any of this stuff?

Topical Cetirizine is probably one of the more popular/affordable ways of inhibiting PGD2 (I believe it also releases PGE2), I assume if it goes systemic, it could give you whatever sides are associated with it, such as drowsiness, nothing nearly as bad as a 5AR inhibitor.

Castor Oil is good for PGE2, however, there is evidence that it lowers testosterone in rats, so I don't personally use it, not orally anyway.
 

NaNaMaOn

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Topical Cetirizine is probably one of the more popular/affordable ways of inhibiting PGD2 (I believe it also releases PGE2), I assume if it goes systemic, it could give you whatever sides are associated with it, such as drowsiness, nothing nearly as bad as a 5AR inhibitor.

Castor Oil is good for PGE2, however, there is evidence that it lowers testosterone in rats, so I don't personally use it, not orally anyway.

I see that there’s a study currently being conducted comparing 1% Cetirizine to 5% Minoxidil. Has it really been seen to be as effective as minoxidil at promoting new regrowth?

Ah, I didn’t know that, will keep it in mind.
 

Charger

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I see that there’s a study currently being conducted comparing 1% Cetirizine to 5% Minoxidil. Has it really been seen to be as effective as minoxidil at promoting new regrowth?

Ah, I didn’t know that, will keep it in mind.
There is a study on it's PGD2 inhibiting properties with pictures of results here: https://sci-hub.se/https://pubmed.ncbi.nlm.nih.gov/28604133/#
Raising PGE2 in rats: https://pubmed.ncbi.nlm.nih.gov/7741033/

As far as it being comparable to minoxidil, can't say, we'll have to wait for that study. But the pictures in the first study seem to show pretty significant results, imo. Min never did anything for me other than make my face puffy and give heart palpitations.
 

NaNaMaOn

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There is a study on it's PGD2 inhibiting properties with pictures of results here: https://sci-hub.se/https://pubmed.ncbi.nlm.nih.gov/28604133/#
Raising PGE2 in rats: https://pubmed.ncbi.nlm.nih.gov/7741033/

As far as it being comparable to minoxidil, can't say, we'll have to wait for that study. But the pictures in the first study seem to show pretty significant results, imo. Min never did anything for me other than make my face puffy and give heart palpitations.

Wow, promising results indeed, maybe I should give this stuff a try. Have you a similar positive experience with the drug? Yeah I’d really rather not mess with my heart like that, which is why I have steered clear of Minoxidil entirely.
 

Charger

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Wow, promising results indeed, maybe I should give this stuff a try. Have you a similar positive experience with the drug? Yeah I’d really rather not mess with my heart like that, which is why I have steered clear of Minoxidil entirely.

I've not been on it longterm to give it a fair assessment. I have PGE2 powder coming this week. Ceti/PGE2 will be my base protocol for the forseeable future seeing as I can't utilize 5ARis or AAs and have no interest in doing so.

Westonci had promising results with Seti (PGD2 inhibitor) and PGE2+Microneedling before dropping it due to religious reasons. You can check his thread here: https://www.hairlosstalk.com/intera...ernative-to-finasteride-and-minoxidil.113910/

In theory, it should be possible to replicate his results, especially since he attributes most of his regrowth to PGE2.
 

Nebula74

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Lol this sucks, but I'd still rather get the sides than lose my hair before my twenties lmao. Also, it's the only affordable treatment for young people when you compare it to RU or CB.

Also, for me, the impact of hair loss is basically the same as finasteride's sides.

It sucks that you have to risk these sides to keep your hair, but if it works and is safe enough to be FDA approved, then I'll use it
 

hemingway_the_mercenary

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Lol this sucks, but I'd still rather get the sides than lose my hair before my twenties lmao. Also, it's the only affordable treatment for young people when you compare it to RU or CB.

Also, for me, the impact of hair loss is basically the same as finasteride's sides.

It sucks that you have to risk these sides to keep your hair, but if it works and is safe enough to be FDA approved, then I'll use it
Might as well use bicalutamide then because finasteride is very unlikely to stop all your hairloss if you started before your 20s. Speaking from personal experience
 

hemingway_the_mercenary

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I thought that bicaliutamide was a prostate cancer treatment lol, did you try dutasteride before moving to bicaliutamide?
Yep. If you started balding thst early you need to suppress more AR signaling than just what comes from DHT. Sad to say but you’re probably fucked, don’t put your hopes into finasteride or dutasteride, they won’t hold you over past 25
 
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