Rapamycin has been getting press for inducing authophagy. The anti-aging folks are all geeked about. You can read about it around those forums. Have also heard that dude Peter Attia talking about it on some podcasts.
This mouse study squeegee posted shows results from applying rapamycin topically. I've though about trying to get some rapamycin powder and mixing in a topical once a week (seems like consensus is you want to apply a single dose ~weekly of rapamycin). I'm currently trying to figure out the world of ordering molecules from China.... alternatively you can get a prescription for pills of it, it was originally approved as a organ transplant drug
https://www.sciencedirect.com/science/article/pii/S2211124719306990