Cyproterone Acetate (androcur)+diane 35 Lotion Urgent!!

[cesarcielo]

Hallo people..I m sorry for not being here..Im just not in the mood after this disaster..So long story short my lotion still aint working and im seeing an endocrinologist next week hopefully ill get a clear plan on what to do..So all this time i quit the lotion totally and i made a search through papers.It seems that im not the only one who is experiencincing an abrupt ineffectiveness of topical hormone lotion.It seems tat many women on topical hrt experience tisphenomenon in a period of 6 months to 1 year or even more.What is more disturbing is that there is not enough scientific data on what some particians call "tachyphylaxis"..I m not in the mood explaining it but there are many controversies on even the official existence of this phenomenon much more a clear definition on it.Some people say that correlates with desensization if skin hormone receptors while some others claim that it has to do with some kind of skin tolerance on the specific substance that makes the dermal stop absorbing it...SOme other call it dermal fatigue,adrenal fatigue so i cant clear this out alone without specialist advice...Plus whats ultimately top disturbing is that some claim that is irreversible and have to find another antiandrogen or it takes more than a year to work like it used to to so in both cases i have to find alternatives to cycle between them..I m sorry for not being more detailed but it took me such a mental and physical effort to balance and keep on living and searching about it...

My advice whatever the treatment is..topical or oral...take breaks...dont make constant use of a treatment specialy the topical ones...Me myself i did take breaks 2 days a week and it seems that it wasnt enough...So..i ll check back with you when i have news bad or good from the medic.Till then whoever wants to use the lotion the recipe is exactly as i mentioned in the first page.crush the pills throw them in alcohol lotion wait for a night to dissolve and then apply.

 

[bridgeburn]

Hallo people..I m sorry for not being here..Im just not in the mood after this disaster..So long story short my lotion still aint working and im seeing an endocrinologist next week hopefully ill get a clear plan on what to do..So all this time i quit the lotion totally and i made a search through papers.It seems that im not the only one who is experiencincing an abrupt ineffectiveness of topical hormone lotion.It seems tat many women on topical hrt experience tisphenomenon in a period of 6 months to 1 year or even more.What is more disturbing is that there is not enough scientific data on what some particians call "tachyphylaxis"..I m not in the mood explaining it but there are many controversies on even the official existence of this phenomenon much more a clear definition on it.Some people say that correlates with desensization if skin hormone receptors while some others claim that it has to do with some kind of skin tolerance on the specific substance that makes the dermal stop absorbing it...SOme other call it dermal fatigue,adrenal fatigue so i cant clear this out alone without specialist advice...Plus whats ultimately top disturbing is that some claim that is irreversible and have to find another antiandrogen or it takes more than a year to work like it used to to so in both cases i have to find alternatives to cycle between them..I m sorry for not being more detailed but it took me such a mental and physical effort to balance and keep on living and searching about it...

My advice whatever the treatment is..topical or oral...take breaks...dont make constant use of a treatment specialy the topical ones...Me myself i did take breaks 2 days a week and it seems that it wasnt enough...So..i ll check back with you when i have news bad or good from the medic.Till then whoever wants to use the lotion the recipe is exactly as i mentioned in the first page.crush the pills throw them in alcohol lotion wait for a night to dissolve and then apply.

that sucks dude, and also scary. what do you think you will do now? maybe cycle between spironolactone/dutasteride combination and the Cypro/Diane? Maybe if you waited for a year, the lotion would work again. also, it's f*****g bullshit, every comment of Anty's is deleted on this thread!!

 

[cesarcielo]

that sucks dude, and also scary. what do you think you will do now? maybe cycle between spironolactone/dutasteride combination and the Cypro/Diane? Maybe if you waited for a year, the lotion would work again. also, it's f*****g bullshit, every comment of Anty's is deleted on this thread!!

i guess thats what im gonna have to do...the bad thing is that in my shitty country flutamide and other estrogen except estriol arent sold...so im gonna stuck with spironolactone...anyway im seeing an endocrinologist this week to clear this thing out...im so dissapointed with this outcome..i dont mind you know having sides,or having to deal with lotion aplication and a programme i have to stick withh my whole life...what im so sick of i the thought that my fuckung skin decide to not absorb it and throw in the trash all the progress been made.

 

[dustovshio]

First of all the orignal miracle lotion didn't call for 8x50mg androcur. Second, though cpa does work topically it not as effective that way. Personally I would stay away from the stuff and if you are going to take it get your liver checked every few months. You have to keep in mind all it is doing is effecting the receptors. Maybe there is something in the lotion that is irritating your skin and if it just recently fell out you should be able to grow it back. I personally am on 5mg ru58841 daily at night plus I do eucapil in the morning and take tumeric, progesterone, and a low dosage of dutasteride. I believe the combination of the eucapil and the ru58841 is going to do more than topical cpa. That being said oral cpa prob is going to be more powerful. And I would like to see some proof that estradiol actually does anything. What does it do just prevent T from getting converted to DHT? The studies I read on it didn't seem to be conclusive that it grows hair back. What i have seen is anecdotal evidence only.

 

[bridgeburn]

First of all the orignal miracle lotion didn't call for 8x50mg androcur. Second, though cpa does work topically it not as effective that way. Personally I would stay away from the stuff and if you are going to take it get your liver checked every few months. You have to keep in mind all it is doing is effecting the receptors. Maybe there is something in the lotion that is irritating your skin and if it just recently fell out you should be able to grow it back. I personally am on 5mg ru58841 daily at night plus I do eucapil in the morning and take tumeric, progesterone, and a low dosage of dutasteride. I believe the combination of the eucapil and the ru58841 is going to do more than topical cpa. That being said oral cpa prob is going to be more powerful. And I would like to see some proof that estradiol actually does anything. What does it do just prevent T from getting converted to DHT? The studies I read on it didn't seem to be conclusive that it grows hair back. What i have seen is anecdotal evidence only.

estrogen increases SHBG, and when it gets high enough E causes less testosterone production by negative feedback on the HPG axis.

 

[dustovshio]

SHBG increase free testosterone, and free testosterone can be converted into DHT via 5-AR. Therefore high estrogen is dangerous if the person isn't either a) 5 AR deficient, or b) on 5 AR inhibitor. eunuchs have high progesterone, low estrogen, low dht and keep hair. You may think well females have high estrogen and they keep hair. Not necessarily, if you look at male vs female hormone levels the only significant difference is DHT levels. Yes females have more estrogen than males but it may be like 2:1 whereas males have 10:1 more dht than females.

 

[bridgeburn]

SHBG increase free testosterone, and free testosterone can be converted into DHT via 5-AR. Therefore high estrogen is dangerous if the person isn't either a) 5 AR deficient, or b) on 5 AR inhibitor. eunuchs have high progesterone, low estrogen, low dht and keep hair. You may think well females have high estrogen and they keep hair. Not necessarily, if you look at male vs female hormone levels the only significant difference is DHT levels. Yes females have more estrogen than males but it may be like 2:1 whereas males have 10:1 more dht than females.

SHBG decreases free testosterone. T that is not bound to SHBG is considered free, if you had No SHBG then All of your T would be free. (technically almost all of it because Albumin also attaches to sex hormones but to a much lesser extant)
it's not just amount of estrogen that's important but the T/DHT-- Estrogen ratio. Most of a males testosterone is made by the testicles, which eunuchs don't have, but the adrenal glands also make a little. I don't know what Eunuchs E/T ratio is, but I'm unaware of any evidence that cutting off balls decreases ones Aromatase levels. And if the aromatase levels are unchanged after the procedure then Eunuchs probably have a ratio more towards the Estrogenic side than before..

Experiments done on Eunuchs showed that giving them Testosterone injections caused hairloss. But when you stop giving them T, their hair does not grow back. Their hair loss just stops progressing. If lowering DHT ratio grew back hair then everybody taking dutasteride which lowers over 90% of Dht would grow all their hair back, which usually doesn't happen.

Transgenders that experience amazing regrowth don't get that just because they lower male hormones, but because of the combination of lowering male hormones and increasing Estrogen. And Estrogen has been shown in studies to prolong the anagen phase.

 

[dustovshio]

Ok I agree it slows the hair growth and prolongs the anagen phase, and Ruby also said the same thing that eunuchs don't have regrowth but only halt their hair loss while transgenders regrow. So if we look at the main drugs they take : cpa. estrogen, spironolactone. Now Antydht didn't take estrogen and he regrew, and both ruby and antydht took cpa. So it could be that cpa is causing much of the regrowth and not estrogen. A lot of people do say that estrogen regrows but I don't see the evidence to support it, yes it does prolong anagen, but is that in itself enough to cause the regrowth. possibly, but you'd think there'd be more serious studies done to prove this if it indeed was one of the only substances to cause regrowth it would be studied more, though some would argue it can't be patented in its original form so there is no point, but that is not true I see a lot of random studies done on weird sh*t for no apparent reason other than to study it.

 

[bridgeburn]

Ok I agree it slows the hair growth and prolongs the anagen phase, and Ruby also said the same thing that eunuchs don't have regrowth but only halt their hair loss while transgenders regrow. So if we look at the main drugs they take : cpa. estrogen, spironolactone. Now Antydht didn't take estrogen and he regrew, and both ruby and antydht took cpa. So it could be that cpa is causing much of the regrowth and not estrogen. A lot of people do say that estrogen regrows but I don't see the evidence to support it, yes it does prolong anagen, but is that in itself enough to cause the regrowth. possibly, but you'd think there'd be more serious studies done to prove this if it indeed was one of the only substances to cause regrowth it would be studied more, though some would argue it can't be patented in its original form so there is no point, but that is not true I see a lot of random studies done on weird sh*t for no apparent reason other than to study it.

But Anty did take estrogen. Anyway, I do believe CPA alone can cause regrowth because it actually puts the Estrogen/ androgen ratio more towards the Estrogen side. CPA stops the Testicles from producing T, and since E is made from T. CPA actually reduces both T and E, however CPA also blocks the androgen receptor But it doesn't block the Estrogen receptor. CPA is f*****g powerful! even women and Eunuchs who have low androgen levels don't have their receptors blocked. So you see, if you have enough CPA in your system, then you have Low T and not much of those male hormones that you do have are able to cause any effect.. With low androgen levels and blocked receptors even a little amount of Estrogen becomes much more powerful because there's no male hormone activity to counteract it's estrogenic effects.

 

[dustovshio]

No Anty didn't take estrogen. But yes you are right I just read the SHBH does bind to the free T.

 

[bridgeburn]

No Anty didn't take estrogen. But yes you are right I just read the SHBH does bind to the free T.

he used 1.5mg topical and 2mg oral a day

 

[yourworld001]

No Anty didn't take estrogen. But yes you are right I just read the SHBH does bind to the free T.

They were on a full blown transgender regimen, and must have seriously messed up their hormones by taking 200mg androcur, they fact Anty was getting no side effects from 200mg androcur shows he'd messed up his hormones.

 

[dustovshio]

OK thanks for sharing that its good to know what the most successful people have done. So why did he get banned again.

 

[bridgeburn]

Unless she is a transgender, y are u recommending this?

because he was already using before topically and getting the side effects from it but was still using it Willingly. I'm not reccomending but said it may be more beneficial for hair IF willing to accept the effects.

OK thanks for sharing that its good to know what the most successful people have done. So why did he get banned again.

Admin said because of his behavior, but he didn't explain clearly why. He said that he had 60 lines as a signature?? which i don't ever remember seeing. I think becaise Anty was complaining about censorship and reccomending polish transplant surgeons

 

[sito]

anybody using topical androcur?

 

[Kornel]

Can anyone post how to prepare miracle lotion?

 

[Georgie]

I heard that 17-b did not do sh*t. Estriol seems to be better. Alpicort-F I think. Be carefull with taking hormones like that (I am talking about you taking cypro 3/week). It is not armless...

PAS I MISS YOU

 

[dustovshio]

anybody using topical androcur?

I use around 600 mg /month topically. Seems to work better than RU for me but I have ordered RU and will be using both but I may go off the CPA for a couple months. results are basically just maintaining me at nw2 maybe a lil regrowth I barely have any shedding maybe 1-3 hair a day that I notice (im sure more falls out that I dont' notice)