Apple Polyphenols

OverMachoGrande

Senior Member
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As this will soon be part of my regimen, (due to it being healthy at a stand-alone complex), I want to know what anyone else thinks, and if they have had experience with these before;

http://www.applepolyphenols.com/

http://www.applepoly.com/

Allegedly, These studies claim to be as much as (300%) more effective than Minoxidil at combating M.P.B., if this is indeed true, where's it's due credit?

Bryan & Mister E; your both more than welcome to chime in some input!
 

waynakyo

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nvestigation of the topical application of procyanidin oligomers from apples to identify their potential use as a hair-growing agent
Tomoya Takahashi 1 , Ayako Kamimura 1 , Masayori Kagoura 2 , Masahiko Toyoda 3 & Masaaki Morohashi 3
1 Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co., Ibaraki, Japan
2 Kagoura Dermatologic Clinic, Toyama, Japan
3 Department of Dermatology, Toyama Medical and Pharmaceutical University, Toyama, Japan
Correspondence: Ayako Kamimura, PhD, Tsukuba Research Laboratories, Kyowa Hakko Kogyo Co., 2, Miyukigaoka, Tsukuba, Ibaraki 305–0841, Japan, E-mail: ayako.kamimura@kyowa.co.jp
Copyright © 2005 Blackwell Publishing
KEYWORDS
external application • male pattern baldness • Malus pumila • procyanidin oligomers • scalp
Summary
Abstract Introduction Materials and methods Results and discussion References

Background Procyanidins are a family of condensed tannins, which have been shown to possess hair-growing activity in both the in vitro and in vivo murine models.

Aims We report a 12-month clinical study aimed at treating male pattern baldness by external application of 0.7% apple procyanidin oligomers.

Patients/methods A double-blind clinical test involving a total of 43 subjects was performed. Twenty-one men in the procyanidin group and 22 men in the placebo control group were subjected to analysis. In the first 6 months, we compared the procyanidin and the placebo groups to assess the medicinal effects of procyanidin oligomers. The application time of the procyanidin group was subsequently extended to 12 months, and the time course of its remedial value was examined.

Results The increase in total number of hairs in a designated scalp area of the procyanidin group subjects after the 6-month trial was significantly greater than that of the placebo control group subjects (procyanidin, 3.3 ± 13.0 (mean ± SD)/0.50 cm2; placebo, ?3.6 ± 8.1/0.50 cm2; P < 0.001, two-sample t-test). Time course-dependent improvement in hair density was observed in the procyanidin subjects. No adverse side effects were observed in any of the subjects. Procyanidin therapy thus shows potential hair-growing activity.


anyone is able toe get the full study ?
 

Axl_Rose

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Keep us updated with your results, this interests me.
 

OverMachoGrande

Senior Member
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Polyphenols could very well promote growth, but the mechanism on how it would promote growth would be (I believe) via nitric oxide, instead of influencing hormone levels (like S.H.B.G.). Polyphenols are shown to increase nitric oxide, which is a gas produced in the lining of your veins which promotes vasodilation and reduces cholesterol build-up, which is vital considering M.P.B. is associated with cardiovascular disease---damn cheese burgers!


A fatty diet would diminish your bodies’ natural ability to produce nitric oxide, but a diet low in fat and cholesterol free, high in polyphenols from vegetables and fruit would promote nitric oxide. Alcohol is also a potent vasodilator and nitric oxide inducer; alcohol and polyphenols could act synergistically to reduced atherosclerosis and promote nitric oxide. Red wine is a concentrated powerhouse of polyphenols, phytonutrients and antioxidants and is probably the worlds richest source, I believe that red wine explains the French paradox.
 

waynakyo

Experienced Member
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I have been applying it since 2 days. since it says it promote regrowth i am applying it on one temple (right one). The idea is that if i get any form of regrowth there that could be from Poly.
At the same time i am still using minoxidil, fluridil and more recently RU (mixed with minoxidil) quite everywhere.. from time to time i add a bit of spironolactone to my temples. so i won't declare success with poly unless my right temple shows any growth. next update in 3 months.
PS: it's not itchy and smells quite good. not as concentrate as i would have imagined. it is more difficult to target areas than minoxidil, but not impossible.
 

Axl_Rose

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waynakyo said:
I have been applying it since 2 days. since it says it promote regrowth i am applying it on one temple (right one). The idea is that if i get any form of regrowth there that could be from Poly.
At the same time i am still using minoxidil, fluridil and more recently RU (mixed with minoxidil) quite everywhere.. from time to time i add a bit of spironolactone to my temples. so i won't declare success with poly unless my right temple shows any growth. next update in 3 months.
PS: it's not itchy and smells quite good. not as concentrate as i would have imagined. it is more difficult to target areas than minoxidil, but not impossible.

Did you get the apple polly capsules as well or just the liquid?
 

machman

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What's the progress so far?
I myself am looking to ordering this so any feedback would be very useful.
Thanks
 

purecontrol

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Lord_Justin13 said:
As this will soon be part of my regimen, (due to it being healthy at a stand-alone complex), I want to know what anyone else thinks, and if they have had experience with these before;

http://www.applepolyphenols.com/

http://www.applepoly.com/

Allegedly, These studies claim to be as much as (300%) more effective than Minoxidil at combating M.P.B., if this is indeed true, where's it's due credit?

Bryan & Mister E; your both more than welcome to chime in some input!


Chocamine was far superior and has better medical studies to back it. It also causes Angiogenesis, that is the growth of new blood vessels. Think your hair would like that?
 

riptiduh

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purecontrol said:
Chocamine was far superior and has better medical studies to back it. It also causes Angiogenesis, that is the growth of new blood vessels. Think your hair would like that?

Can you please reference this claim? I googled it and I didn't read anything that came close to that.

For a cheap alternative to the Applepoly Website:
http://www.swansonvitamins.com/SWU301/ItemDetail

Just take 4 at a time and voila! Tell you the truth, I've taken this product for over a year now.. Started using it in my topical instead of internally if that says anything..
 

purecontrol

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riptiduh said:
purecontrol said:
Chocamine was far superior and has better medical studies to back it. It also causes Angiogenesis, that is the growth of new blood vessels. Think your hair would like that?

Can you please reference this claim? I googled it and I didn't read anything that came close to that.

For a cheap alternative to the Applepoly Website:
http://www.swansonvitamins.com/SWU301/ItemDetail

Just take 4 at a time and voila! Tell you the truth, I've taken this product for over a year now.. Started using it in my topical instead of internally if that says anything..


They have the same exact poly phenols, There are two different forms, and if you look at the original hair study the apple does not have enough of that form while the chocamine does and the chocamine is more researched.

Remember chocamine actually grows new capillaries. What you need to search for are the actual polyphenols that are responsible for the hair re-growth.
 

riptiduh

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Please man, for the love of all that is holy, links.

We need links to these studies and claims. I can google all day long and read all day long, but when you site these specific things that I am not finding, I need a link to what you are reading.

Sorry buddy, when I google chocamine and browse to the ends of the earth, nothing about Chocamine and polyphenols is coming up.

http://www.criticalorie.com/2008/chocamine-review/
http://www.rfiingredients.com/chocamine.asp
http://www.nutraplanet.com/product/nutr ... grams.html
http://www.nutraingredients.com/Industr ... ne-patents

There are four links referring to Chocamine and it having nothing to do with Polyphenols; http://www.google.com/search?q=chocamin ... =firefox-a
 

waynakyo

Experienced Member
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try lycos maybe

tried polyphenols.. but wasn't too patient with it.. there are only 24 hours in a day.
 

Jacob

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purecontrol

Established Member
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Sorry, I don't have time to go digging for the studies. Here is more information for you. Apple, Chocamine, Grape Seed Extract, etc... all have what are called Oligomeric proanthocyanidins (OPCs). These are what's doing the actualy work. Now there are many different forms of these OPCs ie B-2 B-3 C-1 etc. Well if you look at the Apple studies, the apple actually does not have a very high amount of the OPC that grows the most amount of hair, and they go on to talk about isolating that OPC for hair growth. Well Chocamine does have more of that OPC.

Also I want everyone to note that OPCs act like a SARM aka an anti-estrogen. Yep, that's right! And that includes Resvertrol, and all.

Now you can find more information.
 

riptiduh

Member
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According to these websites, Grapeseed has the highest concentration of OPCs:
http://www.colonhealth.net/free_reports/opc_faq.htm
http://www.integratedhealth.com/infoabs ... ycdes.html

Huge article on OPCs
http://www.herbs2000.com/h_menu/opc.htm

Journal Cited article on OPCs
http://www.diet-and-health.net/Suppleme ... idins.html

Again, nothing found on Chocamine and OPCs. Every article about OPCs are related to Grapeseed and Pine Bark
http://www.google.com/search?hair loss=en&clie ... =&gs_rfai=
http://www.google.com/search?hair loss=en&clie ... =&gs_rfai=
http://www.google.com/search?hair loss=en&clie ... =&gs_rfai=

I would love to know where you are getting your information from.. Please, please cite your info for the good of everyone that reads these boards. It takes less than ten seconds to type in a website, copy and paste it into a post.
 
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