Yes, as I've said, DHT is produced where it's used, but excessive amounts travel around your body until it finds something to bind to, which are receptors on other parts of the body where a lot of 5AR type 2 enzymes are located. The serum concentration of any hormone declines when the hormones express themselves. Both estrogen and DHT affects the breast tissue. Estrogen activates, DHT deactivates. DHT suppresses the serum concentration of estrogen by countering estrogenic effects, and that's how DHT affects the testosterone/estrogen ratio.Bryan said:Enden said:Howcome the serum concentration of DHT is measurable, and the suppressed DHT level continues to raise one or two weeks after using 1 mg of finasteride then? It's measurable because excessive amounts travels around your body, from one place which is loaded with 5AR type 2 enzymes, to another.
It's certainly measurable, because we've developed good laboratory tests whcih are capable of detecting it. But that doesn't mean that the tiny amounts of DHT in the bloodstream actually do very much to the parts of the body where they aren't actually produced!