Recent content by HelixO

Hmmm... I'd personally recommend finasteride over Minoxidil, as finasteride does more to address the actual cause of loss at the scalp than minoxidil. In your case, I'm worried that simply using needling alongside minoxidil is perhaps upsetting the balance that Minoxidil has been maintaining, or something along...

Interesting - are you using anything else along with the needling? Also I'm curious how often you are needling? BTW - I know a lot of people needle once a week, but truthfully in a dermatology setting, they would never needle that deeply more than 1 once a month, because the deeper you go, the...

Little confused. You have FUE to fill in your hairline, but you used to be NW7 15 years ago? NW7 -> NW2 requires more than just FUE, so what else did you do to get all that hair back? Minoxidil, finasteride? You only describe microneedling, but surely you were doing something else if you regained that...

I don't know much about using laser to treat baldness, since lasers are typically used to destroy hair follicles, but I believe there are certain wavelengths which could be used that wouldn't destroy the follicle. It's best to look for a clinic that specializes in this. Most clinics typically...

Scarring quite literally is fibrosis. It's literally in the definition. "Fibrosis: the thickening and scarring of connective tissue, usually as a result of injury." (google definition) "Scar: A scar is an area of fibrous tissue that replaces normal skin after an injury." (wiki) "Scar: a mark...

Glad you brought that up. It doesn't take long browsing the various MtF forums (namely Susan.org) to see that the vast majority of MtF people do not experience "total" regrowth any more than your typical finasteride/dutasteride user, and the ones that do experience the most dramatic regrowth are those that...

It's pretty well established at this point that there is a connection between DHT and Fibrosis (Collagen build up). Studies have proven that balding areas of the scalp have elevated levels of DHT over non-balding areas. Studies have proven that balding areas of the scalp have up to 4x as much...

Do you know which protein transduction domain sequence was used? I'm sure you're aware that there's multiple variations of the PTD segment, all of which can significantly effect whether or not the molecule is properly uptaken into the cell. The patent alone describes 5 different PTD sequences...

PTD-DBM isn't a drug though, it's a peptide- how has it been linked to cancer? It was only discovered less than a year or 2 ago. Also how did the guy know he had legitimate or clean product? There is no current market supply for it so it's really hit or miss for him to get a legitimate batch of...

There's a number of studies that focus on the WNT pathway by many different authors. In general WNT pathway directly contributes to new follicle creation, and wounding directly stimulates it. The role of the peptide/vaproic as I understand it was just to increase the overall potency of the...

Actually it's been proven that microwounding induces WNT signaling as part of the healing process, which has been shown to directly contribute to "follicular neogenesis", as in the creation of new follicles. This was also proven in the PTD-DBM peptide study. The peptide was shown to promote the...

It can't be called permanent because the effect of DHT is still in play, however I think it can be safely said that microneedling helps regenerate hairs (and scalp) back to a youthful state. Meaning, someone could stop all treatment for a year or so, and still relatively maintain that hair...

Wow that's interesting. The article doesn't fully explain how exactly it gets rid of the fibrosis, only that there is a reduction of it through protein inhibition. It would appear that the implication of this is extremely wide reaching... It could mean companies could make creams of this stuff...

A quick search on google scholar resulted in multiple papers linking fibrosis to male pattern baldness... here's a paper from 2008. https://link.springer.com/article/10.1007/s00403-007-0826-x Dermal fibrosis in male pattern hair loss: a suggestive implication of mast cells "It was found that collagen bundles...

For microneedling on the scalp to work, the wounds need to go deep enough to sufficiently damage the collagen(fibrosis), so that the body can replace it with healthier tissue. The scalp is a lot thicker than the facial skin, and even with Dermatology, to resurface facial scars with...