Some answers from mr Lee himself about Xandrox 15 plus:
...,
I have no objections to your posting my replies on the Internet forums. But they should not be changed in any manner from the Q & A's as they appear below. I have edited the Q&A's slightly to make them a little more understandable and divided them into paragraphs. Your questions are in black. My responses are in blue.
Best wishes,
Richard Lee, M.D.
... wrote:
Hi there,
I was wondering, just how effective the finasteride in your topical is, compared to talking 1,25 mg a day.
Xandrox15-PLUS would be far more effective than finasteride alone or 5% minoxidil + oral finasteride.
There are definite advantages to 'using 948 as compared to 940'. Cost. The benefits of a 15% minoxidil / 5% azelaic acid solution (Xandrox15) are combined with finasteride with little additional cost as compared to the cost of 940 plus 1mg finasteride tablets. Convenience. The use of a high concentration topical minoxidil, combined with agents that decrease the amount of DHT in the scalp utilizes the two FDA safe and proven treatments for male pattern baldness in one medication.
Although topical azelaic acid will prevent the synthesis of DHT in the scalp where it is applied, it does not protect the hair follicles from DHT circulating in the bloodstream. Finasteride applied topically can and does decrease the serum DHT and, although the 5-alpha reductase enzymes in the scalp is primarily Type I, there are also Type II 5AR's in the scalp that the topically applied finasteride inhibits.
Xandrox15-PLUS does allow for systemic absorption of finasteride from a topical application, but the serum levels of finasteride would be less than that from a comparable oral dose. As reported in an article from the British Medical Journal, 'An 0.05% formulation of topical finasteride was well absorbed and lowered the serum dihydrotestosterone concentration by up to 40%. This suggests that the main action of finasteride is to lower circulating dihydrotestosterone through inhibiting production by the prostate, rather than affecting the metabolism of androgen in the hair follicle.' The concentration of finasteride in Xandrox15-PLUS is double the concentration in the study mentioned above. One would expect that 0.1% would be more effective than 0.05%, but we cannot extrapolate your response to the topical versus the oral doses because of the inherently wide biological and pharmacological variations.
Considering that you get a 4 month supply of finasteride for just ~$5.00 more than the cost of Xandrox15, and that the reduction of serum DHT is almost as much as the oral form, it should be worth using Xandrox15-PLUS in lieu of Xandrox15 concomitant with oral finasteride.
What do you guys think? Especially about the first sentence in his answer, it sounds really encouraging for me to stop with fina orraly plus minoxidil 5 percent, and start with the xandrox 15 plus!
