waynakyo
Experienced Member
- Reaction score
- 463
Costsarelis is back writing about wounds in a couple of recently published papers. He are some of the earth shattering findings after 15 years of wait:
"Because a variety of factors, including environmental variables and choice of mouse strains, can affect the outcomes of a WIHN study, the purpose of this article is to provide an overview of the experimental variables that impact WIHN so that experiments between laboratories can be compared in a meaningful manner."
Read: Let's improve our mice models.
pubmed.ncbi.nlm.nih.gov
In another article:
The origin of the stem cells that give rise to a nascent hair follicle after wounding and the role of mesenchymal cells and signaling pathways responsible for this regenerative phenomenon are slowly being elucidated.
pubmed.ncbi.nlm.nih.gov
If someone has access to the latter please let me know.
"Because a variety of factors, including environmental variables and choice of mouse strains, can affect the outcomes of a WIHN study, the purpose of this article is to provide an overview of the experimental variables that impact WIHN so that experiments between laboratories can be compared in a meaningful manner."
Read: Let's improve our mice models.
Wound-Induced Hair Neogenesis Model - PubMed
Skin wounds in adult mammals typically heal with a fibrotic scar and fail to restore ectodermal appendages, such as hair follicles or adipose tissue. Intriguingly, new hair follicles regenerate in the center of large full-thickness wounds of mice in a process called wound-induced hair neogenesis...
pubmed.ncbi.nlm.nih.gov
In another article:
The origin of the stem cells that give rise to a nascent hair follicle after wounding and the role of mesenchymal cells and signaling pathways responsible for this regenerative phenomenon are slowly being elucidated.
Wound-Induced Hair Neogenesis: A Portal to the Development of New Therapies for Hair Loss and Wound Regeneration - PubMed
Adult mammals retain the remarkable ability to regenerate hair follicles after wounding. Wound-induced hair neogenesis (WIHN) in many ways recapitulates embryogenesis. The origin of the stem cells that give rise to a nascent hair follicle after wounding and the role of mesenchymal cells and...
pubmed.ncbi.nlm.nih.gov
If someone has access to the latter please let me know.
