With hair loss, you're never really safe, you never know how things will progress in 5, 10 or 20 years. Another issue is that most people don't realise and take action until we have already lost a lot. While we may regain some, or even a lot, it doesn't mean that we have hair that we're happy with.
I'm definitely happier with hair meds than without, I would be devastated if I was bald now. I know I look better because of the meds, and I appreciate that they exist and are cheap. My grandfather never had that option.
That said, I lost temple hair and it's not coming back. My hairline is not one I'm happy with, and the hair on top, while it has good coverage, is definitely not as thick as the donor zone. Then there's the fact that I don't know what the future holds. I'm still self conscious about my hairline and getting wet hair, I still worry about the future The meds did wonders, I look better, nobody knows I have a receeding hairline (temples at least) because i have bangs. No way could I pull of my hairstyle without the meds, I'd have shaved it by now and I'd be miserable.
So to summarise, way happier with meds, but still not happy.