World Congress For Hair Research 2017 - Posters | HairLossTalk Forums

World Congress For Hair Research 2017 - Posters

Discussion in 'General Discussions, Presentations, and Interviews' started by hellouser, Nov 8, 2017.

  1. hellouser

    hellouser Senior Member My Regimen

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    I don't think I can upload all the images here, there's over 200 pictures so as to not bog down the server, I've put them all on my IMGUR account. I took shots of everything I could. They're in descending order with a couple out of place at the end (couldn't get them without someone standing in front). That said, the best one is about FGF-9, looks like we really need to give it a go ourselves. Here's the link:

    https://imgur.com/a/yeG6R
     
  2. GotHair?

    GotHair? Established Member

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    SO checked them out.
    For Androgenetic Alopecia what seems interesting is WNT10b compound from Bioenx in ITaly.
    And the other one is Korean study with microneedling and FGF-9 (the cocktail had multiple compounds not just FGF-9: e.g. bFGF, VEGF,KGF-2, SCF,IGF-1,SOD-1, noggin peptide).
    However they found no statistical difference in using 0.8mm needle compared to 0.5mm. So basically it comes back to the cocktail itself.
    Also 2 studies for green tea extract, not sure about effiacy...
     
    #2 GotHair?, Nov 8, 2017
    Last edited: Nov 8, 2017
  3. BaldyBalderBald

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    There's one with zinc level on balding scalp dude, thought it might interest you

    https://i.imgur.com/bqKuYoI.jpg
     
  4. BaldyBalderBald

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    https://i.imgur.com/lE1nyx0.jpg

    +1, this one is interesting, WNT/B-Catenin is more and more relevant

    https://i.imgur.com/3M5rzxD.jpg

    JAK inhibitors are so fucking efficient for Alopecia Aerata, 94% regrowth in 12 months :(, if only we had this for Androgenetic Alopecia...

    Other misc but still interesting things about hair anti-aging, gray reversal...could be useful once we get back our hair
     
    #4 BaldyBalderBald, Nov 8, 2017
    Last edited: Nov 8, 2017
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  5. Sworthyy

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  6. BaldyBalderBald

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    You can zoom on the picture, resolution is pretty high
     
  7. Sworthyy

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    I’m having trouble reading the zinc poster
     
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  8. Pasbrillantebrunette

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    lolilol
     
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  9. BaldyBalderBald

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    Yeah well, maybe for my NW7 horseshoe then, still colored and brillant
     
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  10. d3nt3dsh0v3l

    d3nt3dsh0v3l Experienced Member My Regimen

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    https://i.imgur.com/XuwqDdz.jpg
    Fucking. Holy crap. And you only need to use 0.5 mm needles?! That's like so much less pain and danger.

    Need this cocktail + dermapen asap.

    COTS....The FK are you doing bro?? Seriously is Korea already on their version of Follica: Lite Edition?

    upload_2017-11-9_14-34-30.png
    Look at those secondary hairs returning!

    upload_2017-11-9_14-34-10.png

    ff5.png

    Source: https://www.cellcurin.com/science-new-kor

    Google translate on that page says that it was the hair regeneration ampoule that was used: "Cell kyurin three months after using hair regeneration ampoule, hair density, 21.4%, 5.3% increase in thickness"
    But on the english version of the site (https://www.cellcurin.com/hr-ampoule-new-1), the ingredients look nothing like what is stated on the poster. :<
     
    #10 d3nt3dsh0v3l, Nov 9, 2017
    Last edited: Nov 9, 2017
  11. BaldyBalderBald

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    Seems similar results to the Dermaroll + Minoxidil bro (+21% hair count), you don't need to wait
     
  12. Pephair

    Pephair Established Member My Regimen

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    And where does one get growth factor 9?
     
  13. ZZmop

    ZZmop Established Member

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    Is there a definitive guide to dermarolling for those who are balding? I'm a diffuse thinner, not sure if I could do it all over the scalp, don't know where to start with this.
     
  14. BaldyBalderBald

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    The one that westonci made seems great
    https://www.hairlosstalk.com/intera...mizing-growth-and-minimizing-scarring.109363/

    I don't dermaroll myself so i cannot testify, i was referring to the India study about Dermarolling + Minoxidil
     
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  15. d3nt3dsh0v3l

    d3nt3dsh0v3l Experienced Member My Regimen

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    But the min studies use huge needles right, like 1.5 mm? Ow..
     
  16. BaldyBalderBald

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    Indeed, my bad, in my head it was 0.5mm, which is interesting in this paper is that between 0.8mm and 0.5mm, no significant difference in those results.
    India study just gone right through 1.5mm TAKE THAT needles and didn't mention or experience other sizes.
    Maybe 0.5 or 0.8mm with Minoxidil worth a try
     
  17. BaldyBalderBald

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    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064188/

    Yeah it's on murine...i know
    But, something interesting, it seems that repetition is the key

    "We found that the optimal length and cycle of microneedle treatment on hair growth was 0.25 mm/10 cycles and 0.5 mm/10 cycles. Repeated microneedle stimulation promoted hair growth, and it also induced the enhanced expression of Wnt3a, β-catenin, VEGF, and Wnt10b."

    Why no one made a similar paper on human skin...geez
     
  18. ThanksGramps

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    This poster looks like good news for the Tsuji/Riken project: https://i.imgur.com/zurvYuI.jpg

    "Maintenance and long-term expansion of murine skin epithelial stem cells by Wnt signalling pathway"

    Wasn't this one of the major roadblocks that Koh-ei Toyoshima talked about in last year's interview with Organ Technologies? (See Question 1 of https://www.hairlosstalk.com/news/new-research/hair-primordiums-tsuji-organ-interview-sept2016/)

    From the poster, it looks like they were able to multiply epithelial stem cells by 1000x while maintaining their hair inductive property. That's pretty cool. Here's hoping the same process can be used for human epithelial stem cells.
     
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  19. kuba197

    kuba197 Established Member My Regimen

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  20. lemoncloak

    lemoncloak Established Member My Regimen

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    That's literally the no. 1 poster that drew my attention. Very interesting but notice how about 10% of the cells maintain CD34 expression? If I remember well CD34 is a stem cell marker (equivalent to CD200 in humans) so does that mean most cells don't maintain stem cell capacity? Anyone? I've read about assymetric cell division before (https://en.m.wikipedia.org/wiki/Asymmetric_cell_division) which is when a stem cell divides into a stem cell and a somatic cell instead of two stem cells, this is probably to keep stem cell numbers at a controlled, functioning level, I wouldn't be surprised if that is the case in a small fragile niche like the hair follicle. Maybe that is/was one of the hurdles Tsuji faces with epithelial stem cells, getting 1000/1000 stem cells instead of 100/1000.

    On a second note, my God it's crazy how useless 95% of these studies are.. you can tell some of them were published for $$$. The scientific world is crazy inefficient and yet everytime a decent hair loss article comes along in the press people suddenly go "muh cancer, muh resources"!

    BTW @BaldyBalderBald does https://i.imgur.com/5jHLblC.jpg answer any of your questions about wounding and hair direction?

    Oh and nice to see Yokohama uni jump on the bandwagon
     
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