World Congress For Hair Research 2017 - Posters

[hellouser]

I don't think I can upload all the images here, there's over 200 pictures so as to not bog down the server, I've put them all on my IMGUR account. I took shots of everything I could. They're in descending order with a couple out of place at the end (couldn't get them without someone standing in front). That said, the best one is about FGF-9, looks like we really need to give it a go ourselves. Here's the link:

https://imgur.com/a/yeG6R

 

[GotHair?]

SO checked them out.
For Androgenetic Alopecia what seems interesting is WNT10b compound from Bioenx in ITaly.
And the other one is Korean study with microneedling and FGF-9 (the cocktail had multiple compounds not just FGF-9: e.g. bFGF, VEGF,KGF-2, SCF,IGF-1,SOD-1, noggin peptide).
However they found no statistical difference in using 0.8mm needle compared to 0.5mm. So basically it comes back to the cocktail itself.
Also 2 studies for green tea extract, not sure about effiacy...

 

[BaldyBalderBald]

Some are hard to read

There's one with zinc level on balding scalp dude, thought it might interest you

https://i.imgur.com/bqKuYoI.jpg

 

[BaldyBalderBald]

SO checked them out.
For Androgenetic Alopecia what seems interesting is WNT10b compound from Bioenx in ITaly.

https://i.imgur.com/lE1nyx0.jpg

+1, this one is interesting, WNT/B-Catenin is more and more relevant

https://i.imgur.com/3M5rzxD.jpg

JAK inhibitors are so f*****g efficient for Alopecia Aerata, 94% regrowth in 12 months , if only we had this for Androgenetic Alopecia...

Other misc but still interesting things about hair anti-aging, gray reversal...could be useful once we get back our hair

 

[Sworthyy]

There's one with zinc level on balding scalp dude, thought it might interest you

https://i.imgur.com/bqKuYoI.jpg[/QUOTE
I can’t see what the text says ?? Is there a better image .

 

[BaldyBalderBald]

You can zoom on the picture, resolution is pretty high

 

[Sworthyy]

You can zoom on the picture, resolution is pretty high

I’m having trouble reading the zinc poster

 

[BaldyBalderBald]

lolilol

Yeah well, maybe for my NW7 horseshoe then, still colored and brillant

 

[d3nt3dsh0v3l]

https://i.imgur.com/XuwqDdz.jpg
f*****g. Holy crap. And you only need to use 0.5 mm needles?! That's like so much less pain and danger.

Need this cocktail + dermapen asap.

COTS....The FK are you doing bro?? Seriously is Korea already on their version of Follica: Lite Edition?

Look at those secondary hairs returning!

Source: https://www.cellcurin.com/science-new-kor

Google translate on that page says that it was the hair regeneration ampoule that was used: "Cell kyurin three months after using hair regeneration ampoule, hair density, 21.4%, 5.3% increase in thickness"
But on the english version of the site (https://www.cellcurin.com/hr-ampoule-new-1), the ingredients look nothing like what is stated on the poster. :<

 

[BaldyBalderBald]

https://i.imgur.com/XuwqDdz.jpg
f*****g. Holy crap. And you only need to use 0.5 mm needles?! That's like so much less pain and danger.

Need this cocktail + dermapen asap.

COTS....The FK are you doing bro?? Seriously is Korea already on their version of Follica: Lite Edition?

View attachment 69318
LOOK AT ALL THOSE SECONDARY HAIRS RETURN! Such hair diameter. Very wow.

View attachment 69317

View attachment 69319

Seems similar results to the Dermaroll + Minoxidil bro (+21% hair count), you don't need to wait

 

[Pephair]

And where does one get growth factor 9?

 

[ZZmop]

Seems similar results to the Dermaroll + Minoxidil bro (+21% hair count), you don't need to wait

Is there a definitive guide to dermarolling for those who are balding? I'm a diffuse thinner, not sure if I could do it all over the scalp, don't know where to start with this.

 

[BaldyBalderBald]

Is there a definitive guide to dermarolling for those who are balding? I'm a diffuse thinner, not sure if I could do it all over the scalp, don't know where to start with this.

The one that westonci made seems great
https://www.hairlosstalk.com/intera...mizing-growth-and-minimizing-scarring.109363/

I don't dermaroll myself so i cannot testify, i was referring to the India study about Dermarolling + Minoxidil

 

[d3nt3dsh0v3l]

Seems similar results to the Dermaroll + Minoxidil bro (+21% hair count), you don't need to wait

But the min studies use huge needles right, like 1.5 mm? Ow..

 

[BaldyBalderBald]

But the min studies use huge needles right, like 1.5 mm? Ow..

Indeed, my bad, in my head it was 0.5mm, which is interesting in this paper is that between 0.8mm and 0.5mm, no significant difference in those results.
India study just gone right through 1.5mm TAKE THAT needles and didn't mention or experience other sizes.
Maybe 0.5 or 0.8mm with Minoxidil worth a try

 

[BaldyBalderBald]

But the min studies use huge needles right, like 1.5 mm? Ow..

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064188/

Yeah it's on murine...i know
But, something interesting, it seems that repetition is the key

"We found that the optimal length and cycle of microneedle treatment on hair growth was 0.25 mm/10 cycles and 0.5 mm/10 cycles. Repeated microneedle stimulation promoted hair growth, and it also induced the enhanced expression of Wnt3a, β-catenin, VEGF, and Wnt10b."

Why no one made a similar paper on human skin...geez

 

[ThanksGramps]

This poster looks like good news for the Tsuji/Riken project: https://i.imgur.com/zurvYuI.jpg

"Maintenance and long-term expansion of murine skin epithelial stem cells by Wnt signalling pathway"

Wasn't this one of the major roadblocks that Koh-ei Toyoshima talked about in last year's interview with Organ Technologies? (See Question 1 of https://www.hairlosstalk.com/news/new-research/hair-primordiums-tsuji-organ-interview-sept2016/)

From the poster, it looks like they were able to multiply epithelial stem cells by 1000x while maintaining their hair inductive property. That's pretty cool. Here's hoping the same process can be used for human epithelial stem cells.

 

[kuba197]

@Swoop

 

[lemoncloak]

This poster looks like good news for the Tsuji/Riken project: https://i.imgur.com/zurvYuI.jpg

"Maintenance and long-term expansion of murine skin epithelial stem cells by Wnt signalling pathway"

Wasn't this one of the major roadblocks that Koh-ei Toyoshima talked about in last year's interview with Organ Technologies? (See Question 1 of https://www.hairlosstalk.com/news/new-research/hair-primordiums-tsuji-organ-interview-sept2016/)

From the poster, it looks like they were able to multiply epithelial stem cells by 1000x while maintaining their hair inductive property. That's pretty cool. Here's hoping the same process can be used for human epithelial stem cells.

That's literally the no. 1 poster that drew my attention. Very interesting but notice how about 10% of the cells maintain CD34 expression? If I remember well CD34 is a stem cell marker (equivalent to CD200 in humans) so does that mean most cells don't maintain stem cell capacity? Anyone? I've read about assymetric cell division before (https://en.m.wikipedia.org/wiki/Asymmetric_cell_division) which is when a stem cell divides into a stem cell and a somatic cell instead of two stem cells, this is probably to keep stem cell numbers at a controlled, functioning level, I wouldn't be surprised if that is the case in a small fragile niche like the hair follicle. Maybe that is/was one of the hurdles Tsuji faces with epithelial stem cells, getting 1000/1000 stem cells instead of 100/1000.

On a second note, my God it's crazy how useless 95% of these studies are.. you can tell some of them were published for $$$. The scientific world is crazy inefficient and yet everytime a decent hair loss article comes along in the press people suddenly go "muh cancer, muh resources"!

BTW @BaldyBalderBald does https://i.imgur.com/5jHLblC.jpg answer any of your questions about wounding and hair direction?

Oh and nice to see Yokohama uni jump on the bandwagon

 

[BaldyBalderBald]

That's literally the no. 1 poster that drew my attention. Very interesting but notice how about 10% of the cells maintain CD34 expression? If I remember well CD34 is a stem cell marker (equivalent to CD200 in humans) so does that mean most cells don't maintain stem cell capacity? Anyone? I've read about assymetric cell division before (https://en.m.wikipedia.org/wiki/Asymmetric_cell_division) which is when a stem cell divides into a stem cell and a somatic cell instead of two stem cells, this is probably to keep stem cell numbers at a controlled, functioning level, I wouldn't be surprised if that is the case in a small fragile niche like the hair follicle. Maybe that is/was one of the hurdles Tsuji faces with epithelial stem cells, getting 1000/1000 stem cells instead of 100/1000.

On a second note, my God it's crazy how useless 95% of these studies are.. you can tell some of them were published for $$$. The scientific world is crazy inefficient and yet everytime a decent hair loss article comes along in the press people suddenly go "muh cancer, muh resources"!

BTW @BaldyBalderBald does https://i.imgur.com/5jHLblC.jpg answer any of your questions about wounding and hair direction?

Oh and nice to see Yokohama uni jump on the bandwagon

"unidirectional protrusions toward the wound (W)"...yep it matches what Tsuji said about the importance of the wound direction pre DPs cells injections

But i found another study suggesting that Planar cell polarity fails on very large surface wounds, on mice the pattern was going crazy