Whats the best topical DHT inihibitor for diffuse thinning

[LookingGood!]

Jayman,

That's a gross over simplification of the finasteride issue.

Some people are left with a smashing set of breats and a penis only fit for pissing...so dont be too keen to insist that everyone takes it.

Personally, I can't tolerate it and I was lucky to have my gyno reversed, others are not so lucky

SHOW US THE RESEARCH THAT IT ACTUALLY DID THAT????? I THINK THIS IS A GROSS exaggeration!

I think his gyno is not something that needs research. The only point to make here is how soon he saw it coming, and how soon he did something about it.

Yeah he probably took your advise and drank grapefruit juice and increased the absorption rate. LOL :freaked:

 

[Guest]

http://en.wikipedia.org/wiki/Grapefruit_juice[/url]

 

[H/B]

I say go for it DB.

Also, read what Dave001 posted closely:

Why not use finasteride *topically* at a low concentration, instead? Its inhibitory effect on 5alpha-reductase is well characterized; the same cannot be said for the available alternatives such as linoleic acid and great tea extract.

The only published controlled human trial of topical finasteride in Androgenetic Alopecia was by Mazzarella et al. Topical finasteride in the treatment of androgenic alopecia. Preliminary evaluations after a 16-month therapy course. Journal of Dermatological Treatment (1997) 8, 189-192

Subjects applied twice daily one mL of a 0.005% solution of finasteride in a vehicle of 50% ethanol, 25% propylene glycol, and 25% water. Serum levels of the relevant hormones (total and free testosterone, dihydrotestosterone) were measured prior to treatment at baseline and every 3 months thereafter throughout the study; no changes were observed.

Without going into detail, a positive effect on Androgenetic Alopecia was seen in the treated group, while the control group experienced a decline in hair growth status.

The regimen above would cost you almost nothing (obtain the finasteride from overseas, generic Indian mfd.). To maximize success, combine with topical spironolactone (the combination approach may have synergy). Don't waste money on commercial topical formulations of either drug; prepare them yourself.

Now if my math is correct (Dave has corrected me on my math many times - LOL) this would equate to 3mg of finasteride. in 60ml of solution? That's really a small amount. So my adding 3 to 6 pills of 5mg Proscar is overkill relative to that study. Anyway do the math and see if I'm correct because I've exhibited a propensity of doing the math incorrectly!!

.30/60=.005 .30= six 5mg proscar in a 60 ml solution


EDIT
I' wrong. decimal is moved 1 place. so the above is .05% not .005

you got it OB

 

[LookingGood!]

http://en.wikipedia.org/wiki/Grapefruit_juice[/url][/quote:7231c]

 

[Old Baldy]

H/B: Ok, thanks for checking!

 

[CCS]

So what you guys are saying is that there are no alternatives to internal pharmaceauticals, nothing external works? What about all the $#iT College and Bryan post about when it comes to topicals? I work out, body build whatever, and wont risk f****ing with my testosterone, I like my sex drive, so its not worth it to me. Does everyone agree that finasteride is (or dutasteride)the only solution, because thats not what I have been seeing from most of the posts in here.

-DB

plenty of topicals work. the question is how well they work. RU by itself might stop your hair loss where you apply it. If you use just topicals, you will need a combo of the good ones in the right vehicles, and it still is kind of experimental. They will slow down your hair loss, but if you lose some over a year before realizing it is not stopping, that is a year of loss you could have avoided by taking finasteride or dutasteride. And if you take finasteride or dutasteride AND use these topicals, you can regrow a lot.

finasteride and dutasteride will up your testosterone, not lower it. and your odds of having sexual side effects on finasteride are the same as if you are not on it.