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What in the world happened to ASC-J9? It is an AR degrader with huge potential, with low systemic absorption. It was developed by Androscience and passed phase II clinical trials for acne vulgaris. Hasn’t progressed in years.
Yep. Weird af. Their site is a ghost town. I will try to contact themPerhaps they were destroyed by the finasteride mafia lol
AndroScience Corporation
www.androscience.com
this is their contact link if you want to call or email them, though their website has not been touched in like 6 years.
Thanks for the input. Some good points. You say that it is easier to block the AR than degrade it, but I am worried about AR upregulation when one is constantly blocking them. What’s your take on this?they never ever published data on serum half life, I suspect it is too high for long term hair maintenance with low side effects. as it is not easy to degrade AR, a lot of the drug is needed to achieve some effect
Fluridil has the same mode of action but its too weak to have a real impact.its easier to bind to the AR and block androgens