What are your thoughts on UCLA PP405? Do you think it is promising?

[papasmurfwashere]

This article is a long read, so you can skip to the end for the conclusion. In short, these aren't the droids you're looking for. Link is broken

htt ps:/ /medium.com/ @hairypapasmurf/pp405-the-good-the-bad-and-the-ugly-415cbef50894

 

[jondoeuk]

From Kintor Pharma: ''KT-215 is a topical MPC inhibitor under development by the Company. It activates hair follicle stem cells for Androgenetic Alopecia treatment. The mitochondrial pyruvate carrier (MPC) is located in the inner mitochondrial membrane. Studies have shown that when MPC is inhibited by drugs, pyruvate in the cytoplasm cannot enter the mitochondria, thereby increasing LDH (lactate dehydrogenase) activity and activating hair follicle stem cells, ultimately promoting hair growth. MPC has currently been proven to be a highly promising therapeutic target in the field of hair loss. The MPC inhibitor has identified a preclinical candidate compound (PCC) and preclinical research is currently underway for the treatment of Androgenetic Alopecia.''

 

[jondoeuk]

Pelage sent out an email: ''We are excited to provide a brief update on the clinical trials you signed up to hear about through our registry for androgenetic alopecia (pattern hair loss).

Male study

The AWAKEN clinical trial for men with androgenetic alopecia (Androgenetic Alopecia) is on track to launch this fall. Once the study is live, if you are located in one of the geographies where it’s recruiting, we will reach out directly with next steps, including how to see if you may be eligible to enroll.'' https://pelagepharma.com/