Lol dude, if it increase heart rate, that is a BIG side effects . Why you think Minoxidil is not longer used as medicine to treat Hypertension ?!Minoxidil increases your heart rate, take it only in the morning when you're active.
Taking it at night isn't smart, you'll likely have trouble sleeping and get headaches.
I use oral (6 mg) and topical minoxidil (1 mL) in the morning, without side effects.
I would not recommend combining oral and topical minoxil unless you are under the close supervision of a physician. Risk of serious side effects is too great. But presumably you already are since you on oral minoxidil.I take Oral Minoxidil, 2.5 in the morning.
Is it ok to apply topical Minoxidil in the evening?