Totally Stopped hair loss For 15 Years. Now Loosing Like Crazy. Why?

[pegasus2]

Btw i just read your regimen, why such a low dose of spironolactone? 100mg only has 30% chance of gyno, that probably goes up a bit in conjunction with dutasteride though. I thought 25mg would only be effective as a diuretic and wouldn't really do enough to tackle hair loss, you are very well informed though so im probably wrong lol

30% is a lot. The risk is up to 10% on 25mg. Also, those risks are for monotherapy, but I'm on a few other things that could increase that risk. I've taken 50 mg a day a few times, but I'm trying to limit my risk. My main AAs are the three topical ones and oral dutasteride. spironolactone is there to help out a little with blocking the AR, but mostly to block adrenal aldosterone production, and bind to progesterone receptors.

 

[NorwoodingMyWay]

Yet they don't go bald. I guess testosterone doesn't cause hair loss after all.

Wrong. Testosterone does cause hairloss. It is an androgen too after all. The reason people with 5AR deficiency don't suffer from hairloss, is because DHT never started its effects on the hair follicles. So, these hair follicles remain strong against T.





Let me put it in an example : let's pretend that T is jumping from a "1 meter height", and DHT is a "10 meter height". The hair follicles are your legs.
Now, if you have good functioning legs, jumping from the 1m height won't do anything to them, and they'll remain solid. However, jumping from a 10m height will break them. Now, imagine your legs are broken from the 10m height, and you are told to jump from the 1m height with your legs already broken, that 1m height would be very painful. And if you keep jumping from the 1m height with your broken legs, you could never fully heal.






It's all about DHT first weakening the hair follicles, enabling T to have a more profound effect on them.

 

[killDHT]

Wrong. Testosterone does cause hairloss. It is an androgen too after all. The reason people with 5AR deficiency don't suffer from hairloss, is because DHT never started its effects on the hair follicles. So, these hair follicles remain strong against T.





Let me put it in an example : let's pretend that T is jumping from a "1 meter height", and DHT is a "10 meter height". The hair follicles are your legs.
Now, if you have good functioning legs, jumping from the 1m height won't do anything to them, and they'll remain solid. However, jumping from a 10m height will break them. Now, imagine your legs are broken from the 10m height, and you are told to jump from the 1m height with your legs already broken, that 1m height would be very painful. And if you keep jumping from the 1m height with your broken legs, you could never fully heal.






It's all about DHT first weakening the hair follicles, enabling T to have a more profound effect on them.

I know what you want to tell us.But there is no evidence to prove what you said.

 

[NorwoodingMyWay]

I know what you want to tell us.But there is no evidence to prove what you said.

But isn't T an androgen too ?? I fail to see why T wouldn't keep the balding going..





Let's not forget, that T levels exist in 10 times DHT levels in the serum. And even though T binds to the AR with lower affinity, if alot of T molecules bind to the AR, wouldn't it "replace" DHT ??





Edit : This guy proves that T also causes baldness.
https://moreplatesmoredates.com/testosterone-causes-hair-loss/

 

[pegasus2]

Edit : This guy proves that T also causes baldness.
https://moreplatesmoredates.com/testosterone-causes-hair-loss/

You might want to look up the definition of that word. I read that and didn't see any proof.

 

[killDHT]

As time goes on,T is coming less and less in our blood.If T can kill hair，There's a lot more testosterone at 19 than at 39，Why?

 

[michaelle]

Have you tried some medicine? I have been using Propecia lately, and it works pretty well for me. Maybe you should try it out too? Think about it

 

[killDHT]

I have some similar issues, I am pretty worried

I am sorry to hear that.Hairloss after having massive hives?

 

[NorwoodingMyWay]

You might want to look up the definition of that word. I read that and didn't see any proof.

Obviously you didn't read. The guy is on dutasteride, RU and doing TRT. When he removed RU and increased TRT dose, while remaining on dutasteride, his hairloss started picking up pace. He even put his blood test up and it showed his DHT is undetectable (<5 ng/dl), so if it's not DHT, it has to be T.

 

[NorwoodingMyWay]

As time goes on,T is coming less and less in our blood.If T can kill hair，There's a lot more testosterone at 19 than at 39，Why?

Same can be said about DHT. Testosterone is also an androgen, why wouldn't it contribute to ANDROgenic Alopecia ??

 

[NorwoodingMyWay]

Does it? You might want to do some more research.

Yes it does. But whatever, i'll believe that T can still cause hairloss, while you can believe that it can't. Good day mate.

 

[MrClean1]

Did you stop rogaine anytime before this started?

 

[sonictemples]

You never heard of thyroid hair loss, metabolic syndrome, telogen effluvium, PGD2, and so forth? We're talking about a single person here who claims his shedding increased to 50-100 hairs per day in the shower after he did all this stuff to reduce his DHT and then came off RU, and who has supraphysiological levels of testosterone. He doesn't have any photographic evidence that his hair got cosmetically worse. He doesn't even claim that it did. He just found some more hair in the shower, but for how long? A couple days? A week? A year? This is not what one would call a controlled study.

Learn to understand nuance and generalizations. I'm not saying testosterone has zero effect on hair, but that it's minimal which means it alone does not cause male pattern baldness in the majority of people with normal hair loss. Maybe it did in this guy with his supraphysiological T levels, or maybe he had telogen effluvium from the hormonal changes. Who knows? I don't, and neither do you despite your claim to the contrary.

Why do you use RU if you think T cannot cause hair loss? Dutasteride already nukes the DHT

 

[LowHairLine]

Why do you use RU if you think T cannot cause hair loss? Dutasteride already nukes the DHT

DUTA only nukes about 60% of SCALP DHT:

the remaining 40% are still raping follicles,
and they get their a** kicked by RU...

 

[sonictemples]

Nah, i'm just good at memorizing names lol. By the way, it's rich being lectured on how I spend my time by a guy who reached 400+ posts on a hair loss forum in half an year.

An year? They teach better English in primary school lol go hard reset yourself

 

[countjulian]

DUTA only nukes about 60% of SCALP DHT:

the remaining 40% are still raping follicles,
and they get their a** kicked by RU...

Source?

 

[pegasus2]

Why do you use RU if you think T cannot cause hair loss? Dutasteride already nukes the DHT

What lowhairline said about the dht. Also, when going for regrowth it is helpful to reduce all androgens. Even if T alone can't make you bald, it's enough to keep hair from regrowing. The less androgenic activity the better.

 

[goulou]

Thanks for all your answers. Nothing really new for me. Tried topical ceti, tried (again) zix and went to a specialised hospital on hives, but none of these gave interesting results...
I think I'm gonna try to add finasteride to my dutasteride and see... Still moderate hope on this but can't really find anything better right now.

One thing is that my hair hurt whenever I pass my hand though my scalp. If I have just a tiny knot in my hair it really hurts. This reminds me one summer when I forgot my duta for more than a month and my hair started to hurt the same way...

I'll let you know...

 

[goulou]

Well, I've been on my new regimen for 10 days : added daily 1mg finasteride to my 2/week 0,5mg dutasteride and I can definitely say that the pain I've been having this last year each time I pulled slightly my hair is gone.
My "pull pain profile" is back to normal, when my hairloss was stopped.

I can definitely say that this pain has always been associated with hairloss with me, and the lack of pain with halting my hairloss.

So this smells very good... I will see the evolution but I am 85% confident that I've found (for now) the solution.

Didn't expect this as my DHT levels were already sub-normal but I gladly take the surprise...

I'll let you know how things are going...

 

[PaulLSSH]

15 years of dutasteride is a long time, did you not suffer side effects all that time? I'm 19 and I'm afraid to start finasteride.