Does anyone have experience with applying topical rapamycin?
I have some rapamycin powder and want to try applying topically as part of my regimen. I'm not what sure would be an appropriate concentration or dosage schedule however.
This study is what gave me the idea:
https://www.cell.com/cell-reports/pdfExtended/S2211-1247(19)30699-0
This is how they describe the treatment, granted it is a mouse study:
My ignorance speaking but any idea how the above would translate into topical solution? Maybe something like 0.1% ? Dosing is further complicated by the apparent negative effects from doing too much or too frequently with rapamycin. I think consensus among people taking rapamycin orally is something like ~5mg one time per week.
The study is pretty interesting in that it explores the role of autophagy in hair growth. It seems promising in triggering telogen hairs into anagen but less clear what if any effects autophagy has on dormant/miniaturizing hair cells.
I have some rapamycin powder and want to try applying topically as part of my regimen. I'm not what sure would be an appropriate concentration or dosage schedule however.
This study is what gave me the idea:
https://www.cell.com/cell-reports/pdfExtended/S2211-1247(19)30699-0
This is how they describe the treatment, granted it is a mouse study:
My ignorance speaking but any idea how the above would translate into topical solution? Maybe something like 0.1% ? Dosing is further complicated by the apparent negative effects from doing too much or too frequently with rapamycin. I think consensus among people taking rapamycin orally is something like ~5mg one time per week.
The study is pretty interesting in that it explores the role of autophagy in hair growth. It seems promising in triggering telogen hairs into anagen but less clear what if any effects autophagy has on dormant/miniaturizing hair cells.