Topical Bicalutamide (bla Bla Bla Bla Bla) | HairLossTalk Forums
Dismiss Notice
Forum Update: Aug 19. Feedback for the Admin? Upgrade coming: Click Here.

Topical Bicalutamide (bla Bla Bla Bla Bla)

Discussion in 'Antiandrogens - Propecia, Dutasteride, etc.' started by Kevand, Jul 6, 2017.

  1. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    Hi!
    I am going to try topical bicalutamide. I have dissolved 70 mg bicalutamide in 500 ml vodka (40 % alcohol), which makes a concentration of ~ 0,015 %.

    I have tried topical spironolactone 0,1-1 % with good regrowth, unfortunately it had strong systemic side effects. Dramatically reduced body hair, reduced libido and more. I got much regrowth in just 3-4 weeks for about 8 months ago. Since then I have lost huge ground and I tried topical spironolactone for about 1 month recently. Systemic sides were less still thinned body hair and reduced libido but less, but no regrowth this time.

    I've gone through various reviews of the side and life quality effects of bicalutamide and surprisingly sexual sides are more uncommon than common with a dose of 50-150mg a day while the gyno ratio is though very high (60 %).
    Will report effects here!
     
  2. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    I might up the dose to 1 mg/ml, more than that I will need arimidex for safety and prevention and other vechile than ethanol. I got tamoxifen in hand but will not use for prevention.
     
  3. Medina

    Medina Established Member My Regimen

    Joined:
    May 30, 2017
    Messages:
    469
    Likes Received:
    751
    Dislikes Received:
    21
    My Regimen:
    My Regimen
    My Regimen
    Good luck.

    What spironolactone did you use? Do the sides go away when stopping?
     
  4. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
  5. Medina

    Medina Established Member My Regimen

    Joined:
    May 30, 2017
    Messages:
    469
    Likes Received:
    751
    Dislikes Received:
    21
    My Regimen:
    My Regimen
    My Regimen
    I always heard spirol was too weak. I really want some quick regrowth.

    We are doing Enzalutamide experiment. Any thoughts on that? And where did you get the Bic from?
     
  6. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    Yeah spironolactone is probably very weak. I think the reason spironolactone maybe worked for me then was because although I lost much hair it was very recent loss, so it was enough to reverse the dht damage. Also It seems I am sensitive to AA.

    I am following the enzalutamide thread. Very impressed by the result of the EOD use and every second week use. Probably the AR signaling inhibiton mechanism other than ar-antagonism played a big role in the regrowth. Bicalutamide can as well degrade the AR-receptor but enzalutamide is 5-10x stronger in RAA and can also inhibit AR translocation. All in all enzalutamide should be more effective. Bicalutamide is easier to purchase, to store, handle, mix and better documented of safety thats why I think it's better option to experiment first.
     
  7. Medina

    Medina Established Member My Regimen

    Joined:
    May 30, 2017
    Messages:
    469
    Likes Received:
    751
    Dislikes Received:
    21
    My Regimen:
    My Regimen
    My Regimen
    Godammit you have intrigued me now.

    Can you PM me your source and prices?
     
  8. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    Done mate!
     
    Medina likes this.
  9. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    I was gonna wait 1 week to get rid of spironolactone from my system, but couldn't wait trying the formula yesterday. It removed the itch and got that numb scalp feeling so i think vodka is enough as a vechile. I get this feeling with high dose spironolactone and hope this is an indication of it working.
     
  10. Medina

    Medina Established Member My Regimen

    Joined:
    May 30, 2017
    Messages:
    469
    Likes Received:
    751
    Dislikes Received:
    21
    My Regimen:
    My Regimen
    My Regimen
    I thought it was too good to be true. The side effect profile of Bic is quite severe dude.

    I'm talking penis shrinkage and liver and lung toxicity.
     
  11. FCKW36

    FCKW36 Experienced Member

    Joined:
    Nov 17, 2014
    Messages:
    963
    Likes Received:
    615
    Dislikes Received:
    116
    Why not trying Enza?
     
    Medina likes this.
  12. hairblues

    Joined:
    Apr 28, 2016
    Messages:
    8,473
    Likes Received:
    8,844
    Dislikes Received:
    365
    My Regimen:
    My Regimen
    My Regimen
    I use topical spironolactone..it slowed down my hair loss but did not stop it.

    adding topical finasteride .5% next to see if this helps.
     
    Medina likes this.
  13. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    Those are risks associated with every NSAA and are fairly uncommon, bicalutamide is the most benign if you compare with flutamide and nilutamide. And certainly enzalutamide have this risks too. With low dose topical this should minimize the risks. Not familiar with penis shrinkage? Where u read this mate?
     
  14. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    I wrote above; bicalutamide is easier to purchase, to store, handle, mix and better documented of safety thats why I think it's better option to experiment first.
     
  15. Medina

    Medina Established Member My Regimen

    Joined:
    May 30, 2017
    Messages:
    469
    Likes Received:
    751
    Dislikes Received:
    21
    My Regimen:
    My Regimen
    My Regimen
  16. Kevand

    Kevand Established Member

    Joined:
    Jun 18, 2016
    Messages:
    160
    Likes Received:
    45
    Dislikes Received:
    0
    You could try topical bicalutamide in your minoxidil? Very easy drop the pill and it will dissolve by itself. NSAA are generally well tolerated among females and I assume you have the benifit of anny feminization effect in complete contrast to us males ;)
    Finasteride worth a try tho.
     
    hairblues likes this.
  17. hairblues

    Joined:
    Apr 28, 2016
    Messages:
    8,473
    Likes Received:
    8,844
    Dislikes Received:
    365
    My Regimen:
    My Regimen
    My Regimen
    we can get sides from surpassing testosterone...its an imbalance hormonally so we can get moody, breast pain, weight gain, hot flashes, period unscheduled, goes on...Of course I think a topical these are less likely or at least not as severe.
     
  18. Medina

    Medina Established Member My Regimen

    Joined:
    May 30, 2017
    Messages:
    469
    Likes Received:
    751
    Dislikes Received:
    21
    My Regimen:
    My Regimen
    My Regimen
    Pretty standard then :D
     
  19. hairblues

    Joined:
    Apr 28, 2016
    Messages:
    8,473
    Likes Received:
    8,844
    Dislikes Received:
    365
    My Regimen:
    My Regimen
    My Regimen
    Pretty standard when interacting with you, I am sure :p
     
  20. FCKW36

    FCKW36 Experienced Member

    Joined:
    Nov 17, 2014
    Messages:
    963
    Likes Received:
    615
    Dislikes Received:
    116
    Dude come on, what are you talking about? Your penis won't change the length from using an anti-androgen topical.
     
    ForeverLacey and hairblues like this.

Share This Page