The science of intermittent fasting

Afro_Vacancy

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Do you think Indian food is healthy for people because it's hard to digest? It doesn't stay
in the body for a long time.

Would that make it like calorie restriction? Or is the damage done once we over eat for a long
period of time?

Part of me wants to fast, but I'm borderline diabetic.

I'm really concerned that if I do it, I will lower my metabolism down. Or is there no truth in that?

What I've seen of Indian restaurants is that they use a huge amount of heated vegetable oils and simple carbs. As such the food is inflammatory, raises insulin, and overall not ideal. I think that Indian restaurants are for the most part enablers of diabetes. If you love Indian food and you want to be healthy, your only options are to either eat it much less often, or cook it at home in a manner that adjusts the recipes. When you cook it at home, you can restrict the carbohydrates/sugars, use better fats, and use more vegetables.

There are good aspects to Indian food. For example ghee (clarified butter) is wonderful for heated foods, but it's expensive so I doubt Indian restaurants use it. Cauliflower, keffir, yogurt, etc are all wonderful. Stay away from the breads.

Now with respect with your metabolism, total fasting (as in no calories consumed, but please take water) increases metabolism by about 10% within a few days. However, if you're consuming a small amount of carbs and proteins, you never get the metabolic advantages of fasting, your insulin doesn't drop and your human growth hormone doesn't rise, and thus your body cannot convert adipose fat into energy and your metabolism just drops. There are lots of studies which show that low-calorie diets just reduce metabolism.

If you're pre-diabetic, here are two choices for you:

1) Reduce simple sugars, eat more healthy fats instead like avocado, oily fish, nuts, olives, coconut, eggs, meat, etc, and do some exercise especially high-intensity cardio and resistance training;
2) Do some long fasts, I suspect that 36 hours is the minimum for therapeutic advantages, as in eat a dinner on Saturday night and then eat a breakfast on Monday morning. 60 hours is better than 36, and 84 hours is better than 60 hours.

1 and 2 are not mutually exclusive, but one may be easier for you due to psychological issues.
 

rclark

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What I do know is that white rice does cause diabetes, which is in Indian food, and a lot of
Asian restaurants do carry white rice.. But so do a lot of things, like
diet soft drinks (Diet Coke, Diet Pepsi).

It's funny, I have friends with type two diabetes, which is reversible. And I think that it's
because they have stationary jobs, which they do forty hours a week.
 

rclark

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What I've seen of Indian restaurants is that they use a huge amount of heated vegetable oils and simple carbs. As such the food is inflammatory, raises insulin, and overall not ideal. I think that Indian restaurants are for the most part enablers of diabetes. If you love Indian food and you want to be healthy, your only options are to either eat it much less often, or cook it at home in a manner that adjusts the recipes. When you cook it at home, you can restrict the carbohydrates/sugars, use better fats, and use more vegetables.

There are good aspects to Indian food. For example ghee (clarified butter) is wonderful for heated foods, but it's expensive so I doubt Indian restaurants use it. Cauliflower, keffir, yogurt, etc are all wonderful. Stay away from the breads.

Now with respect with your metabolism, total fasting (as in no calories consumed, but please take water) increases metabolism by about 10% within a few days. However, if you're consuming a small amount of carbs and proteins, you never get the metabolic advantages of fasting, your insulin doesn't drop and your human growth hormone doesn't rise, and thus your body cannot convert adipose fat into energy and your metabolism just drops. There are lots of studies which show that low-calorie diets just reduce metabolism.

If you're pre-diabetic, here are two choices for you:

1) Reduce simple sugars, eat more healthy fats instead like avocado, oily fish, nuts, olives, coconut, eggs, meat, etc, and do some exercise especially high-intensity cardio and resistance training;
2) Do some long fasts, I suspect that 36 hours is the minimum for therapeutic advantages, as in eat a dinner on Saturday night and then eat a breakfast on Monday morning. 60 hours is better than 36, and 84 hours is better than 60 hours.

1 and 2 are not mutually exclusive, but one may be easier for you due to psychological issues.

Thank you. That's very good advice. Definitely going to try the two options above.
 

Afro_Vacancy

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What I do know is that white rice does cause diabetes, which is in Indian food, and a lot of
Asian restaurants do carry white rice.. But so do a lot of things, like
diet soft drinks (Diet Coke, Diet Pepsi).

It's funny, I have friends with type two diabetes, which is reversible. And I think that it's
because they have stationary jobs, which they do forty hours a week.

The rice used in Indian restaurants is typically basmati rice, as far as white rice goes it's actually one of the better ones. Given your current health state, you should avoid it, but once your health improves it's good for you to know that basmati rice is actually one of the better ones.

Diet soda should be avoided. I now drink it less than once a month.
 

Afro_Vacancy

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A friend in medical school asked me for this, it's a bibliography of fasting studies.

General and Classics:

Some references taken from here:
https://authoritynutrition.com/10-health-benefits-of-intermittent-fasting/

Jason Fung's fasting series, Part II (linked here is colloquiual), parts 3 and 4 are very technical, and it goes on
https://intensivedietarymanagement.com/fasting-physiology-part-ii/

Article on a 20-day fast that made the cover of Harper's a while back:
http://media.wix.com/ugd/03997d_422ba2e2c279e899b8d1c3de71f1b1e7.pdf

Features of a successful therapeutic fast of 382 days' duration
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2495396/

Medically supervised water-only fasting in the treatment of hypertension.
https://www.ncbi.nlm.nih.gov/pubmed/11416824

Medically supervised water-only fasting in the treatment of borderline hypertension.
https://www.ncbi.nlm.nih.gov/pubmed/12470446

Fasting: the history, pathophysiology and complications.
https://www.ncbi.nlm.nih.gov/pubmed/6758355

Miscellany on Human Growth Hormone, Autophagy, Norepinephrine, Etc.

A randomized pilot study comparing zero-calorie alternate-day fasting to daily caloric restriction in adults with obesity.
https://www.ncbi.nlm.nih.gov/pubmed/27569118

Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC329619/

Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men.
https://www.ncbi.nlm.nih.gov/pubmed/1548337

Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man.
https://www.ncbi.nlm.nih.gov/pubmed/3127426

Resting energy expenditure in short-term starvation is increased as a result of an increase in serum norepinephrine.
https://www.ncbi.nlm.nih.gov/pubmed/10837292

Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism.
https://www.ncbi.nlm.nih.gov/pubmed/15640462

Metabolic regulation of Sirtuins upon fasting and the implication for cancer.
https://www.ncbi.nlm.nih.gov/pubmed/24048020

Caloric restriction and intermittent fasting: Two potential diets for successful brain aging
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2622429/

Short-term fasting induces profound neuronal autophagy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106288/

Mitochondrial degradation by autophagy (mitophagy) in GFP-LC3 transgenic hepatocytes during nutrient deprivation.
https://www.ncbi.nlm.nih.gov/pubmed/21106691

Prolonged Fasting reduces IGF-1/PKA to promote hematopoietic stem cell-based regeneration and reverse immunosuppression
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102383/

Fasting and Weighlifting

Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males
http://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-1044-0

Time-restricted feeding in young men performing resistance training: A randomized controlled trial.
https://www.ncbi.nlm.nih.gov/pubmed/27550719

Krista Varady's Research on Alternate-Day Fasting

Dietary and physical activity adaptations to alternate day modified fasting: implications for optimal weight loss.
https://www.ncbi.nlm.nih.gov/pubmed/20815899

Short-term modified alternate-day fasting: a novel dietary strategy for weight loss and cardioprotection in obese adults.
https://www.ncbi.nlm.nih.gov/pubmed/19793855

Alternate day fasting for weight loss in normal weight and overweight subjects: a randomized controlled trial.
https://www.ncbi.nlm.nih.gov/pubmed/24215592

Improvements in LDL particle size and distribution by short-term alternate day modified fasting in obese adults.
https://www.ncbi.nlm.nih.gov/pubmed/20880415

Intermittent fasting combined with calorie restriction is effective for weight loss and cardio-protection in obese women.
https://www.ncbi.nlm.nih.gov/pubmed/23171320

Safety of alternate day fasting and effect on disordered eating behaviors.
https://www.ncbi.nlm.nih.gov/pubmed/25943396

Alternate day fasting increases LDL particle size independently of dietary fat content in obese humans.
https://www.ncbi.nlm.nih.gov/pubmed/23612508

Alternate day fasting and endurance exercise combine to reduce body weight and favorably alter plasma lipids in obese humans.
https://www.ncbi.nlm.nih.gov/pubmed/23408502

Alternate day fasting (ADF) with a high-fat diet produces similar weight loss and cardio-protection as ADF with a low-fat diet.
https://www.ncbi.nlm.nih.gov/pubmed/22889512

Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations.
https://www.ncbi.nlm.nih.gov/pubmed/20300080

Benefit of a low-fat over high-fat diet on vascular health during alternate day fasting.
https://www.ncbi.nlm.nih.gov/pubmed/23712283

Meal timing during alternate day fasting: Impact on body weight and cardiovascular disease risk in obese adults.
https://www.ncbi.nlm.nih.gov/pubmed/25251676

Effect of exercising while fasting on eating behaviors and food intake.
https://www.ncbi.nlm.nih.gov/pubmed/24176020

Changes in hunger and fullness in relation to gut peptides before and after 8 weeks of alternate day fasting.
https://www.ncbi.nlm.nih.gov/pubmed/27062219

Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulations.
https://www.ncbi.nlm.nih.gov/pubmed/23113919

Effects of weight loss via high fat vs. low fat alternate day fasting diets on free fatty acid profiles.
https://www.ncbi.nlm.nih.gov/pubmed/25557754

Modified alternate-day fasting and cardioprotection: relation to adipose tissue dynamics and dietary fat intake.
https://www.ncbi.nlm.nih.gov/pubmed/19375762

Determinants of weight loss success with alternate day fasting.
https://www.ncbi.nlm.nih.gov/pubmed/26385599

Alternate-day fasting reduces global cell proliferation rates independently of dietary fat content in mice.
https://www.ncbi.nlm.nih.gov/pubmed/19084375

Impact of intermittent fasting on glucose homeostasis.
https://www.ncbi.nlm.nih.gov/pubmed/27137896

Alternate-day fasting and chronic disease prevention: a review of human and animal trials.
https://www.ncbi.nlm.nih.gov/pubmed/17616757

Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism, and plasma adiponectin levels in mice.
https://www.ncbi.nlm.nih.gov/pubmed/17607017

Dose effects of modified alternate-day fasting regimens on in vivo cell proliferation and plasma insulin-like growth factor-1 in mice.
https://www.ncbi.nlm.nih.gov/pubmed/17495119

Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction.
https://www.ncbi.nlm.nih.gov/pubmed/19195863

Modified alternate-day fasting regimens reduce cell proliferation rates to a similar extent as daily calorie restriction in mice.
https://www.ncbi.nlm.nih.gov/pubmed/18184721

Effects of different degrees of insulin resistance on endothelial function in obese adults undergoing alternate day fasting.
https://www.ncbi.nlm.nih.gov/pubmed/28035343

Valter Longo's research, mostly focused on the fast-mimicking diet and applications to cancer treatment, the immune system, and life extension

Here's a TEDx talk by Valter Longo

Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes.
https://www.ncbi.nlm.nih.gov/pubmed/28235195

Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease.
https://www.ncbi.nlm.nih.gov/pubmed/28202779

Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence.
https://www.ncbi.nlm.nih.gov/pubmed/28137612

Impact of intermittent fasting on health and disease processes.
https://www.ncbi.nlm.nih.gov/pubmed/27810402

Fasting and Caloric Restriction in Cancer Prevention and Treatment.
https://www.ncbi.nlm.nih.gov/pubmed/27557543

Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity.
https://www.ncbi.nlm.nih.gov/pubmed/27411588

Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan.
https://www.ncbi.nlm.nih.gov/pubmed/27304506

Safety and feasibility of fasting in combination with platinum-based chemotherapy.
https://www.ncbi.nlm.nih.gov/pubmed/27282289

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.
https://www.ncbi.nlm.nih.gov/pubmed/27239035

Fasting plus tyrosine kinase inhibitors in cancer.
https://www.ncbi.nlm.nih.gov/pubmed/26645151

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.
https://www.ncbi.nlm.nih.gov/pubmed/26094889

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition.
https://www.ncbi.nlm.nih.gov/pubmed/25909220

Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models.
https://www.ncbi.nlm.nih.gov/pubmed/25909219

Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression.
https://www.ncbi.nlm.nih.gov/pubmed/24905167

Fasting: molecular mechanisms and clinical applications.
https://www.ncbi.nlm.nih.gov/pubmed/24440038

Fasting enhances the response of glioma to chemo- and radiotherapy.
https://www.ncbi.nlm.nih.gov/pubmed/22984531

Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy.
https://www.ncbi.nlm.nih.gov/pubmed/22323820

Fasting and differential chemotherapy protection in patients.
https://www.ncbi.nlm.nih.gov/pubmed/21088487

Fasting and cancer treatment in humans: A case series report.
https://www.ncbi.nlm.nih.gov/pubmed/20157582

Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index.
https://www.ncbi.nlm.nih.gov/pubmed/20145127

Fasting and the Brain

Tedx talk by Mark Mattson, one of the dominant researchers here:

Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment.
https://www.ncbi.nlm.nih.gov/pubmed/24886300

Intermittent fasting attenuates inflammasome activity in ischemic stroke.
https://www.ncbi.nlm.nih.gov/pubmed/24805069

Chronic Intermittent Fasting Improves Cognitive Functions and Brain Structures in Mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670843/
Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.
https://www.ncbi.nlm.nih.gov/pubmed/11220789

Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice
http://onlinelibrary.wiley.com/doi/10.1046/j.0022-3042.2001.00747.x/abstract

Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.
https://www.ncbi.nlm.nih.gov/pubmed/11220789

Energy intake, meal frequency, and health: a neurobiological perspective.
https://www.ncbi.nlm.nih.gov/pubmed/16011467

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151440/

The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022308/

Age and Energy Intake Interact to Modify Cell Stress Pathways and Stroke Outcome
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844782/

Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.
https://www.ncbi.nlm.nih.gov/pubmed/17306982

Reversal of cognitive decline: A novel therapeutic program
http://www.aging-us.com/article/100690

Caloric restriction and intermittent fasting: Two potential diets for successful brain aging
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2622429/

Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.
https://www.ncbi.nlm.nih.gov/pubmed/10398297

A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.
https://www.ncbi.nlm.nih.gov/pubmed/23276384

Intermittent fasting: A “new” historical strategy for controlling seizures?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740951/

Bonus: Discussion of Coffee, Diabetes, and Weight Control
http://www.bodyrecomposition.com/re...etes-and-weight-control-research-review.html/

@JeanLucBB this was arguably the most useful post in this thread.
 

rclark

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This just in, intermittent fasting (six hundred calories a day) actually reverses type two diabetes!

Was talking to a friend of mine who has that. He was telling it was not reversible, and I was fucked (I'm on
my way, not there yet).

We will see about that. I plan on

1. Running (jogging) a half mile every day!

2. Always taking the steps at work (I'm running them, and I have twelve flights of stairts, ten
steps each (not big ones, third floor/ 120 steps).

3. Eat GLUTEN FREE. That's right, I'm having Cheerios and Skim Milk for breakfast
everyday.

And, the best thing is, people DON'T NEED BARIATRIC SURGERY (OR ANY SURGERY) TO DO THIS!

It's here: http://care.diabetesjournals.org/content/36/4/1047
 

rclark

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@rclark you could eat organic black rice and cook with coco oil (which stays quite stable while heated). Also don't drink soda nor industrial/bottle orange juice.

You're SO RIGHT about that Pasbrillantebrunette. But I love diet soft drinks,
which have proven to be JUST AS BAD, if not worse in some ways.

Easier said than done, I suppose. I cut them out, but not all of them.
 

SteveTabernack

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You're SO RIGHT about that Pasbrillantebrunette. But I love diet soft drinks,
which have proven to be JUST AS BAD, if not worse in some ways.

Easier said than done, I suppose. I cut them out, but not all of them.

Not true crazy man
 

Afro_Vacancy

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Is 36hours fast with tea/water enough to attack your organ fat ? Given that you do it once per week?

Im generally interested in fasting bc hgh boost and loss of organ fat seems legit but i dont want to lose to much weight in a short time spane since it can highlight your ageing

http://www.dailymail.co.uk/health/article-1247315/How-face-reveals-traumas-youve--ageing-faster.html

Longer fasts are better. There's a threshold where fasting improves a lot after ~18 hours, that means that in a 36 hour fast you get 18 hours of greatness, whereas in a 60-hour fast you get 42 hours of greatness. There's another threshold after 3 days.

Regardless, if you want a relative reduction of organ fat, the following strategies will be effective:
- Fasting regularly of any length, though longer is better. 36 hour fasts once a week will yield dividends after a couple months.
- This also includes breaks between meals rather than constant snacking.
- Resistance training and high-intensity interval training.
- A diet that involves more complex carbs, fats, fiber, and fewer simple carbs and in particular less fructose. It's possible that fructose is much less bed when consumed with fiber.
- Bonus: Have a little bit of vinegar prior to meals involving carbohydrates. Multiple studies have shown that it blunts and slows the insulin and glucose response to carb-rich meals.

I'm currently on the third day of a fast, I have not eaten since Sunday night other than sparkling water, coffee, tea, and a bit of cream and lime juice for flavouring, I hope to go on until Friday. I'm mostly doing it for compensation as I have non-stop travelling and social events from Thanksgiving (a month ago) through to mid-February.
 

Saulus

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Longer fasts are better. There's a threshold where fasting improves a lot after ~18 hours, that means that in a 36 hour fast you get 18 hours of greatness, whereas in a 60-hour fast you get 42 hours of greatness. There's another threshold after 3 days.

Regardless, if you want a relative reduction of organ fat, the following strategies will be effective:
- Fasting regularly of any length, though longer is better. 36 hour fasts once a week will yield dividends after a couple months.
- This also includes breaks between meals rather than constant snacking.
- Resistance training and high-intensity interval training.
- A diet that involves more complex carbs, fats, fiber, and fewer simple carbs and in particular less fructose. It's possible that fructose is much less bed when consumed with fiber.
- Bonus: Have a little bit of vinegar prior to meals involving carbohydrates. Multiple studies have shown that it blunts and slows the insulin and glucose response to carb-rich meals.

I'm currently on the third day of a fast, I have not eaten since Sunday night other than sparkling water, coffee, tea, and a bit of cream and lime juice for flavouring, I hope to go on until Friday. I'm mostly doing it for compensation as I have non-stop travelling and social events from Thanksgiving (a month ago) through to mid-February.


How much weight do you lost so far?

I assume if u fast 36 once per week the weightloss wont be that dramatic? (Im not intending to lose much weight, 1-2 kg fat would be nice tho)
 

Saulus

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Oh and when you fast only drinking water/tea during this time is the most efficient way right? Compared to juice diat for example
 

Afro_Vacancy

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How much weight do you lost so far?

I assume if u fast 36 once per week the weightloss wont be that dramatic? (Im not intending to lose much weight, 1-2 kg fat would be nice tho)

Oh and when you fast only drinking water/tea during this time is the most efficient way right? Compared to juice diat for example

My peak weight was 240 lbs, I started fasting around 200 lbs, now I'm 175 lbs. My fasting schedule is irregular, and I often eat badly when not fasting which should be my priority at this point.

Water/tea/coffee/salt is likely most efficient, many people say only filtered water and maybe salt but I'm not convinced. A juice diet has different advantages. It loads you up on micronutrients, and it might be good for the digestive system. But a lot of people don't lose weight on it, or if they do it doesn't stay off.

Recommendation to you: just do one 36-hour fast to see how it goes.

For dinner, have a non-sugary, non-starchy meal, for example steak and Brussel sprouts, or salmon and broccoli, or eggs and avocado, whatever. If you're a vegan have beans, tofu, and spinach, or something. Then the next day consume nothing but water, sparkling water, tea, coffee, and then write down your experiences the day after when you have a normal breakfast.

The first fast won't transform you physically, but you'll see how it affects you physically. Note that it's common to get tired the first time, your body isn't used it. Since you're athletic it shouldn't be so bad for you.
 

Saulus

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@Afro_Vacancy


Im 6'4 and was always between 87-96 kg in the last years..i was over 100kg 8 years ago..felt like sh*t..especially since i have a genetically determined very bad fat distribution meaning that i store all my fat at the belly and neck and nothing at the legs/butt..probably a ton of visceral fat too

This is why weight or bmi are not really that important..its more about fat/muscle ratio and esprcially fat distribution

Will definitely try 36h fast now


What is your opinion on sulforaphan?

https://www.foundmyfitness.com/news...cteria_increasing_mitochondria_in_fat_in_mice

It may have a good effect on dht too
 

Afro_Vacancy

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@Afro_Vacancy


Im 6'4 and was always between 87-96 kg in the last years..i was over 100kg 8 years ago..felt like sh*t..especially since i have a genetically determined very bad fat distribution meaning that i store all my fat at the belly and neck and nothing at the legs/butt..probably a ton of visceral fat too

This is why weight or bmi are not really that important..its more about fat/muscle ratio and esprcially fat distribution

Will definitely try 36h fast now


What is your opinion on sulforaphan?

https://www.foundmyfitness.com/news...cteria_increasing_mitochondria_in_fat_in_mice

It may have a good effect on dht too

Sulforophane is promising but I'd like to see more research.
What I've seen of that drug is good, but I'm honestly skeptical of all research published on herbs, etc. Part of that is that in my time on this hair loss forum I've learned that hair loss has been nearly cured so many times: pumpkin seed oil, saw palmetto, rice bran oil, he shon wu, laminar japonica, distance tubulosa, etc etc etc. I despair that the herbal medicine literature may be overwhelmingly bullshit.

Let me know how things go for you.

I also put fat on my neck/jaw and it's annoying, as it's arguably the ugliest kind of fat.
 

Saulus

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Sulforophane is promising but I'd like to see more research.
What I've seen of that drug is good, but I'm honestly skeptical of all research published on herbs, etc. Part of that is that in my time on this hair loss forum I've learned that hair loss has been nearly cured so many times: pumpkin seed oil, saw palmetto, rice bran oil, he shon wu, laminar japonica, distance tubulosa, etc etc etc. I despair that the herbal medicine literature may be overwhelmingly bullshit.

Let me know how things go for you.

I also put fat on my neck/jaw and it's annoying, as it's arguably the ugliest kind of fat.


Yeah i dont mean regarding hairloss but regarding visceral fat..with mice the results looked promising..but again..mice
 
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