The science behind topical DHT inhibitors?

[bodysnatcher]

I thought Propecia and other oral finasterides worked by entering your bloodstream.

How do these topical DHT inhibitors work?

Have any studies been done?

If so then why are they not regaurded as highly as the big 3?

Which are the best ones?

Do they bring a shed? even if you are also on finasteride?

Any known side effects? are they similar to the oral DHT inhibitors?

Level with me, are they worth it?

Thanks

 

[Bryan]

I thought Propecia and other oral finasterides worked by entering your bloodstream.

They do.

How do these topical DHT inhibitors work?

By inhibiting the conversion of testosterone into DHT within hair follicle cells.

Have any studies been done?

Yes. A few.

If so then why are they not regaurded as highly as the big 3?

It's difficult to find good drugs (and good topical vehicles to deliver them) which penetrate well into the skin/scalp, without having a significant systemic effect.

Which are the best ones?

Good question, and highly controversial. In my own opinion, topical fatty acids may be the best all-around choice.

Any known side effects? are they similar to the oral DHT inhibitors?

Should be similar.

Level with me, are they worth it?

Another highly controversial question!

Bryan

 

[iamnaked]

Good question, and highly controversial. In my own opinion, topical fatty acids may be the best all-around choice.

Holy liposomic inhibition, Batman! What might be an example of a topical fatty acid DHT blocker?

 

[JWM]

Revivogen is the only one I know of.

 

[science-jay]

Revivogen is the only one I know of.

the only problem is:

1. it's extremely smelly and greasy.
2. there are not many users who have had succes with it.
3. because they've put al active ingredients they thought of in 1 bottle they can rule each other out.
4. some suspicious people are working for the revivogen company

super-zix and spironolactone first!

 

[Lessofarockstar]

Bryan, why is p-r-ocerin then considered a scam. With the following ingredients in it, shouldnt it be considered a very effective topical?
I have no experience with it, but it seems to be considered useless here on HairLossTalk.com.

Ingredients:
SD alcohol 40, Oleic Acid, Linoleic Acid, Alpha Linoleic Acid, Azelaic Acid, Primrose Oil, Avacado Oil , Saw Palmetto Extract, Grape Seed Extract, Gamma Linoleric Acid, Pygeum Bark Extract, Stinging Nettle Leaf Extract, Toocopheral, Zinc Sulphate, Pyridoxine.

Does anybody know exactly why it gets starred out when you write it? Has it been proved to be a scam? It seems somewhat similar to revivogen...

 

[science-jay]

Bryan, why is p-r-ocerin then considered a scam. With the following ingredients in it, shouldnt it be considered a very effective topical?
I have no experience with it, but it seems to be considered useless here on HairLossTalk.com.

Ingredients:
SD alcohol 40, Oleic Acid, Linoleic Acid, Alpha Linoleic Acid, Azelaic Acid, Primrose Oil, Avacado Oil , Saw Palmetto Extract, Grape Seed Extract, Gamma Linoleric Acid, Pygeum Bark Extract, Stinging Nettle Leaf Extract, Toocopheral, Zinc Sulphate, Pyridoxine.

Does anybody know exactly why it gets starred out when you write it? Has it been proved to be a scam? It seems somewhat similar to revivogen...

on Hairlosstalk.com there is a tendency to put down non-proven treatments...

there is nothing wrong with that, proven things first, i agree.

the only strange thing is that REVIVOGEN is so positively evaluated on this site bij the HairLossTalk.com-moderater and Bryan. I think it has something to do with selling the stuff on this site, HairLossTalk.com has to make a living too ofcourse...

 

[Guest]

YEAH.. Its sad that they don´t admit it.. but I can understand it tough :lol: Money talks and hairlocks falls!!

I would consider Dutas as the best topical DHT inhibitor!! Thats what am gonna try.. dutasteride + Aloe.. The Double A..

Unless someone can prove it is not the best??

 

[Bryan]

Bryan, why is p-r-ocerin then considered a scam. With the following ingredients in it, shouldnt it be considered a very effective topical?
I have no experience with it, but it seems to be considered useless here on HairLossTalk.com.

Ingredients:
SD alcohol 40, Oleic Acid, Linoleic Acid, Alpha Linoleic Acid, Azelaic Acid, Primrose Oil, Avacado Oil , Saw Palmetto Extract, Grape Seed Extract, Gamma Linoleric Acid, Pygeum Bark Extract, Stinging Nettle Leaf Extract, Toocopheral, Zinc Sulphate, Pyridoxine.

I'm not familiar enough with the product to have much of an opinion. I haven't bothered to read any of the threads about it.

It does appear to be similar to Revivogen, but I can't help but wonder just how deep the similarity goes. Does it contain as much of the active ingredients as Revivogen? Are the fatty acids and the other things in the proper form to be effective? I have no idea...

Does anybody know exactly why it gets starred out when you write it? Has it been proved to be a scam?

There's probably some bad blood between the HairLossTalk.com admin and the makers of that product. I don't know any details of that.

Bryan

 

[Bryan]

the only strange thing is that REVIVOGEN is so positively evaluated on this site bij the HairLossTalk.com-moderater and Bryan. I think it has something to do with selling the stuff on this site, HairLossTalk.com has to make a living too ofcourse...

I can't speak for HairLossTalk.com's motivations, of course, but I think I made it clear in my article "Random Reflections on Revivogen" that it was based mainly on theoretical considerations and some animal experiments. Like everyone else, I wish to god that we could FINALLY have some independent testing of that product, so that we could once and for all put an end to all the controversy around it.

Bryan

 

[science-jay]

the only strange thing is that REVIVOGEN is so positively evaluated on this site bij the HairLossTalk.com-moderater and Bryan. I think it has something to do with selling the stuff on this site, HairLossTalk.com has to make a living too ofcourse...

I can't speak for HairLossTalk.com's motivations, of course, but I think I made it clear in my article "Random Reflections on Revivogen" that it was based mainly on theoretical considerations and some animal experiments. Like everyone else, I wish to god that we could FINALLY have some independent testing of that product, so that we could once and for all put an end to all the controversy around it.

Bryan

i agree testing is the only thing that will stop controversy...
until then i'm going to stick with either proven or cheap & unproven

 

[ShedMaster]

Bryan, so do you think spironolactone can inhibit DHT just as well as propecia?