Taking Finasteride 0.25 For Dupa (diffuse Unpatterned Alopecia)

[Maxx79]

Firstly many doctors think miniturisation is only caused by dht. But they are wrong miniaturisation can also happen with alopecia areata. You can check articles.

I think you are probably slowly thinning and maybe you think you benefit from Propecia? I didn’t find the picture of anyone who benefited from propecia.


Why I think it’s not dht related?

1-Many guys who posted on hairloss forums about dupa 80% of the cases didn’t benefit from dht blockers.

Even the doctor which claims 50% cases benefit from propecia don’t have pics to us to provide evidence...

2-A year after the start of my dupa I started to have vitiligo. If you search articles alopceia areata and vitiligo have similar pathogenisis. Both autoimmune related.

Thanks for the detailed reply. I notice that you mention alopecia areata, but that's not the same as DUPA, is it?

In my understanding Alopecia areata is baldness in patches, and thought to be due to auto-immune causes, while DUPA is a form of androgenetic alopecia with overall thinning (so following the same mechanisms as "normal" male pattern baldness except no zone is safe from DHT as our hair in back and on the sides isn't DHT resistant).

 

[Mehmet1234]

In my opinion I think DUPA is not androgen related because of the reasons I mentioned above ( most people do not respond to antiandrogens)

I believe DUPA is a form of diffused alopecia areata (autoimmune). In diffused alopecia areata hairs all over the scalp is affected. That’s is why I believe miniturisation that we experience is due to autoimmune attack. For instance you are miniaturising slowly, mine is very fast and as I said before a year after that I had vitiligo which is giving us the sign that DUPA might be autoimmune not androgen related.

 

[Mehmet1234]

Man by the way aloepcia areata has a form called diffused alopecia areata which is not patchy loss but diffused loss all over the scalp.

 

[Maxx79]

In my opinion I think DUPA is not androgen related because of the reasons I mentioned above ( most people do not respond to antiandrogens)

I believe DUPA is a form of diffused alopecia areata (autoimmune). In diffused alopecia areata hairs all over the scalp is affected. That’s is why I believe miniturisation that we experience is due to autoimmune attack. For instance you are miniaturising slowly, mine is very fast and as I said before a year after that I had vitiligo which is giving us the sign that DUPA might be autoimmune not androgen related.

Alopecia comes in many forms and with different causes / factors, and I believe we both have different cases of DUPA.

If it helps anyone else who found this thread searching for DUPA, have a search on youtube for " Jose Lorenzo DUPA " . As far as I know he's the only surgeon who specializes in DUPA patients. He's treated a lot of DUPA sufferers over the years and he requires they commit to a medical treatment (finasteride or duta) before and after the surgery, to stabilize the donor, which is essential in DUPA patients.

 

[WithinReach]

Am I crazy or Cavill has the same thing?

 

[Hamza]

I wish I had got onto it much easier but I was told finasteride would help but it didn’t

Hey, I also am suffering from DUPA. I was fortunate enough to notice my hairloss when I was 18 ( I'm 19 now so this was actually 6 months ago ) and I went to a hair loss specialist right away. They highly recommend staying away from medication due to the side effects and risks of permanent effects so I did. Currently I am doing Low level laser treatment for 20 minutes sessions 2 times a week as well as taking Saw Palmetto, Zinc, Omega 3, Biotin, B-Vitamins, vitamin D and silica Supplements 3 times a day. I also use the Nioxin shampoo conditioner and treatment system. Before I started I was losing hair rapidly I'd say over 200 a day and my hairline became an NW2 within a month and a half. Currently about 5 months into my program my hair has stopped falling out as quickly but it is still thinning so I guess it's kind of working. However at this point it's pretty obvious I'm just delaying the inevitable. My doctor said if all goes well the laser and supplements should halt my hairloss fully within a years time and since my hairloss would be stopped (or I guess slowed down substaintionally) I'd be Eligible for a transplant to replace the hair I did lose. I'm not sure if this is true or if it will work, however my doctor says medications are Just not worth it and it's my only option. Just wanted to hear some thoughts on this. Thanks for reading.

 

[Hamza]

In my opinion I think DUPA is not androgen related because of the reasons I mentioned above ( most people do not respond to antiandrogens)

I believe DUPA is a form of diffused alopecia areata (autoimmune). In diffused alopecia areata hairs all over the scalp is affected. That’s is why I believe miniturisation that we experience is due to autoimmune attack. For instance you are miniaturising slowly, mine is very fast and as I said before a year after that I had vitiligo which is giving us the sign that DUPA might be autoimmune not androgen related.

Did you find any cure

 

[Hamza]

DUPA sufferer here, I am trying nuclear options. Went in for a blood test, to see if dht is inhibited and t levels.

Also if its worth anything, my scalp was extremely extremely greasy. It was extremely uncomfortable. I would wash my head, and within 2 hours it would get oily. Shampoo would get it 6 hours. I begged doctors to look at it seriously, all they would do is write a shampoo or tell me it can't be helped. FFS. Only my current regime helped with that, so I'm grateful.

No thickening for me, but no hairfall either. So even if I don't get my hair back, I plan to continue for a peaceful scalp.

What treatments are you taking I have the same problem where scalp gets greasy and Iose hair and have to shampoo all the time. Do you have any treatments

 

[Mehmet1234]

What treatments are you taking I have the same problem where scalp gets greasy and Iose hair and have to shampoo all the time. Do you have any treatments

How long did you been on finastride?
Are you experiencing thinning and shedding all over scalp?

 

[beebah]

Hi

I'm new here. I hope I'm not highjacking the thread now. I think I have dupa as well since my hair appears to be thinner on the sides and in the back of the neck. I've also lost hair on my crown and hairline. So, what do you guys think.

Thanks

 

[Has]

Hi

I'm new here. I hope I'm not highjacking the thread now. I think I have dupa as well since my hair appears to be thinner on the sides and in the back of the neck. I've also lost hair on my crown and hairline. So, what do you guys think.

Thanks

My best guess would be a receding hairline.

 

[Screeech]

Hi

I'm new here. I hope I'm not highjacking the thread now. I think I have dupa as well since my hair appears to be thinner on the sides and in the back of the neck. I've also lost hair on my crown and hairline. So, what do you guys think.

Thanks

Looks like retrograde alopecia to me.

 

[camille leprevost]

Hello, just to recap, I am a man and have DUPA hair loss (or female pattern hair loss), diffuse hair loss and thinning (back, sides and top) which started 3 years ago after an episode in my life where my alimentation was very bad and had nutrient deficiency for sure. After fixing my alimentation properly my hair are still shedding and thinning all over.

Since 8 month i only take 1mg finasteride / day (no reduction on my hair loss), cb0301 30mg topicaly with no reduction on my hair loss, Biotin (10mg/day), spearmint tea (4 cup/day to reduce free testosterone), Flaxseed (30 g/day to reduce testosterone)

Here is a complete blood test that I have done 3 weeks ago. It would be great if some of you may highlight some issue in it and maybe propose corrective action as he might help others with similar hair loss.

From my perspective, I think I have low zinc, low vitamin d, high prolactin level, high cortisol level and maybe iron deficiency as we can have it according to study even with normal level of blood iron.

BLOOD TEST of the 04.12.2020

Vitamin B12 : 812 ng/l (197-771)
Vitamin A : 0.5 mg/l (0.1-1)

IONIC BALANCE

Sodium : 139 mmol/l (136-145)
Potassium : 4 mmol/l (3.5-4.5)

PROTEIN

Albumin : 47 g/l (40-49)

RENAL FUNCTION

Urea : 46 mg/dl (17-48)
Creatinine : 0.94 mg/dl ( 0.7-1.2)
DFG (CKD-EPI) >90 mL/min/1.73m^2

LIVER/PANCREAS

AST(GOT) : 16 UI/L (<40)
ALT(GPT) : 10 UI/L (<41)
alkaline phosphatase : 55 UI/L (40-129)
Gamma GT : 10 UI/L (10-71)
LDH : 178 UI/L (135-225)
Biribulin total : 0.8 mg/dl (<1.2)
Biribulin conjugated : 0.3 mg/dl (<0.2)

CARDIOVASCULAR RISK FACTOR

Triglyceride : 68 mg/dl (<150)

CARBOHYDRATE METABOLISM

Fasting glucose level : 96 mg/dl (70-100)
Insulin : 39.7 mg/dl (17.8-173)
Index HOMA1-IR : 1.4 pmol/l (<2.4)

TYROID

TSH : 1.35 mu/l (0.27-4.20)
T4 libre : 17.8 pmol/l (12-22)

ADRENAL GLAND

Cortisol (morning test) : 480 nmol/l (166-507)

CALCIUMPHOSPHATE METABOLISM

Bioactive PTH (3nd gen) 25.5 ng/l < 49
25 OH vitamin D : 14.8 μg/l (30-80)

ENDOCRINOLOGY

Total prolactin : 18.2 μg/l (4-15.2)
Bioactive prolactin : 14.9 μg/l (3-11.6)
LH : 5.8 UI/L (1.7-8.6)
FSH : 1.9 UI/L (1.5-12.4)
Oestradiol : 30 ng/l (25-52)
Progesterone : 0.24 μg/l < (0.15
17OH-Progesterone : 3 ng/ml (0.9-3.4)
total Testosterone : 20.80 nmol/l (8.64-29)
Testosterone free: 509.1 pmol/l (260-740)
Androstanediol glucoronide 2.8 nmol/l (4-75)
Delta 4 androstenedione : 1.4 ng/ml (0.1-3)
DHEA-S : 4.72 μmol/l (4.34 – 12.20)
SHBG : 24 nmol/l (18.3-54.1)
DHT : I don’t have the result yet

TOXICOLOGY

Zinc : 72 μg/dl (80-120)

BLOOD

Haemoglobin : 16.6 g/dl (13-18)
Red blood cell : 5.40 10^6/μl (4.40-5.90)
Hematocrit : 45.5% (40-53)
mean corpuscular volume : 84 fL (80-100)
mean corpuscular HB : 30.6 pg (26-34)
mean corpuscular haemoglobin concentration : 36.5 g/dl (31-35)
anisocytose indice : 12% (11.5-13.4)
platelet : 208 10^3/ μl (150- 440)
mean platelet volume : 10.1 fL (8.9-12.9)
white blood cell : 7.16 10^3/ μl (3.5-11)
neutrophiles : 62.1% (40-75)
neutrophiles (absolute): 4.44 10^3/ μl (1.5-6.7)
Lymphocytes : 25.4% (20-45)
Lymphocytes (absolute) : 1.82 10^3/ μl (1.2 – 3.5)
Monocytes : 10.6 % (2-10)
Monocytes (absolute) : 0.76 10^3/ μl (0.2 - 1)
Eosinophiles : 1.5% (2-10)
Eosinophiles (absolute) : 0.11 10^3/ μl (<0.4)
Basophiles : 0.4% (0-1)
Basophiles (absolute) : 0.03 10^3/ μl (<0.1)

INFLAMMATORY SYNDROM

Crp : <0.5 mg/dl (<5)

ANEMIA

Iron : 134 μg /dl (65-175)
Transferrin : 216 mg/dl (215 – 365)
Transferrin saturation : 44% (16-44)
Ferritin : 120 μg/l (30-300)
Folic acid : 4.8 μg/l (>4.6)
Folic acid erytrocytaire : 754 μg/l GR (523-1257)