Shiseido - Rch01 Clinical Trial Pdf

HairSuit

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What nonsense?
Please, elaborate.

Why do you take this seriously?
I don't.

Arguments and facts matter.
The rest is to just kill time from time to time.
I'm fully aware of what I write and what that content leads to.
It's fun!
Chill out, bro.

Ps. I love being confrontational and a contrarian.
I’m sorry...... let me get another whiskey and maybe I’ll understand this better...... why do I take it so seriously? HAHAHAHA. Let me read back through your many, many defensive responses. But with my low IQ, I still may not get it. Hold please........
 

James Oliver

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Of course, it sucks.
But a bald woman suffers a lot more than a 35-year-old dude.
Lots of women grow up with bald dads, so they are attracted to us.
Not all of them, but a lot of them.
How many of us would date a bald or balding woman?
I certainly would not.
Yeah i agree. When you start surpassing 30, especially mid 30's i dont think its as bad, it's quite common. But for someone who is in their early twenties when your trying to get experience with girls/find a partner... it can be quite a hit to your looks at that age. Ages you a lot, so you date older women right? Well they like men their age or older generally.
 

That Guy

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You are right, but most men lose their hair after the age of thirty.
I lost mine at 29 and my wife and I had been already together when it happened.
Her dad is bald and she doesn't mind.
She wishes I had hair, too, but me going bald was not really an issue.
If she had an issue, we wouldn't have babies together, would we?

Did you have your babies before or after you went bald?
 

nahte42

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You are right, but most men lose their hair after the age of thirty.
I lost mine at 29 and my wife and I had been already together when it happened.
Her dad is bald and she doesn't mind.
She wishes I had hair, too, but me going bald was not really an issue.
If she had an issue, we wouldn't have babies together, would we?

Sounds like you were together a good while before you lost your hair, though. That allowed you to operate at full confidence to start and the bond to build based on that.

Not crying over here, because compared to many my life is fine, but I as a human have a complete failure of hair genes. My hair was already sh*t quality at age 12 and I literally started going bald at 14-15. By 18, the horseshoe pattern was already coming out in full swing. I would not wish this failure of genes on anyone else. It's been horrific. It comes from my father's side. My grandfather lost most of his hair in his 20s-30s, my dad the same, and for some reason the gene decided to accelerate itself by a whole decade for me. Not 20s. Teens. I just want people to understand how awful this is. It constantly makes me feel like I'm a genetic failure. I really looked forward to being a dad some day because I like kids and would really enjoy the role, but at the same time I'm not sure because I do not want to pass on this pathetic biological trait to them.
 

Fuji Maru Kagurazaka

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『Shiseido & RepliCel A near-futuristic hair regenerative medicine RCH-01 Official announcement of safety and improvement!』
http://hairlosscure100.blog.fc2.com/blog-entry-315.html

毛髪再生医療による男女の壮年性脱毛症の新たな治療法の開発.JPG


kagurazakafujimaru.jpg
 

Joxy

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Shiseido trials only showed our reality. It is very hard to grown hairs.
 

Throwaway94

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I like that Shiseido are still pushing this as an effective treatment despite the disappointment from the hair loss community. Even though it's barely maintenance a press release like this indicates they might still want to commercialise after all.
 

MrV88

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From Shiseido/Follicle thought

“In this clinical study, we confirmed the safety and effectiveness of cell therapy technology and we aim to develop cell therapy for a wide range of people suffering from sickness and thinning hair.”

[Future research development and ripple effects]
“In this clinical study, S-DSCTM was injected only once into a small area of the thinning hair to increase the effective cell concentration. Decided and confirmed safety. However, in order to actually use it in clinical practice,It must be administered multiple times throughout the thinning hair area to show a visible therapeutic effect and safety. We will conduct clinical research for this purpose in the future.”



Maybe they're going to add some of their own research and so on, who knows, still seems like sh*t or they didn't go full scale, just a small injection
 

Milkonos

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lol, Shiseido RCH01 was the only reason why I subscribed to this forum. Now there is nothing holding me back to this forum
 

Tom4362

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Does anyone still have the link to the thread with all those hilarious memes?
 

Janks16

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For what it's worth.

Shiseido Releases RCH-01 Trial Results 2020

Update (3/9/20) : Shiseido May Still Pursue RCH-01
Today, a joint press release from Tokyo Medical University, Toho University, and Shiseido Co. was shared with me. This press release was issued on March 6, 2020 and contains details about the RCH-01 trial results which were also published online last week. Tokyo Medical University and Toho University are the two institutions which carried out the RCH-01 trials in conjunction with Shiseido. The press release contains some interesting quotes which are likely unexpected by most of the audience. Let’s take a look at what was said:

“In this clinical study, we confirmed the safety and effectiveness of cell therapy technology and we aim to develop cell therapy for a wide range of people suffering from sickness and thinning hair.”


[Future research development and ripple effects]
“In this clinical study, S-DSCTM was injected only once into a small area of the thinning hair to increase the effective cell concentration. Decided and confirmed safety. However, in order to actually use it in clinical practice,It must be administered multiple times throughout the thinning hair area to show a visible therapeutic effect and safety. We will conduct clinical research for this purpose in the future.”


Shiseido and their co-institutions clearly state that they aim to develop the cell therapy to offer it to patients in the future and they will conduct clinical trials using RCH-01 (S-DSCTM) in the future. I think many people would have guessed that Shiseido was done with dermal sheath cup therapies after the modest results from their trial, however, that may not be the case according to this press release. It’s quite a turn of events, what do the readers think about this latest statement from Shiseido? Comment below.
 

topicalthunder

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I do think these companies are missing the bigger picture here... I’d love a relatively side effect free maintenance treatment.

If something like this could provide maintenance for 1-2 injections a year, I could go get a FUE and no longer worry about hairloss. Such a shame really!
 

MeDK

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Quite the contrary. I understand that most people aren't going to be interested in even trying it like I am, and most people can't afford it like I can. It's going to be at least $900 every six months, and the plane ticket and hotel will triple that. By the time it became available in the west we would have hair multiplication as long as Tsuji's work comes through, plus we have sideless maintenance with Breezula. You're overestimating people's fear of pills. Americans LOVE their pills. They don't care about potential sides because it's so convenient. Personally I'd prefer not to take pills. I don't even take Tylenol or cold medicine, but for hair I will take a pill.

why every six months when peak it around 9 month mark?

tsuji is so far away that it doesn't make sense, no proof of concept in humans no need to think about it as an option.
 

MeDK

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I'm just going with what everyone else is figuring on. 6 months vs 9 months doesn't really matter. That's a strawman, the argument remains the same. Besides, results level off 6 months even if they peak at 9, so 6 months may be better than 9 anyways.

If Tsuji starts human trials this month then all that changes. Six months from now we could have proof that it works in humans, and that's a game changer. I know you're a doubter when it comes to hair multiplication, but we will see who is right in time.

If we go by the graph, the at 6 months it wouldn't be better, if lower dose is better than medium and high doses. So could be there is something to the case about "oversaturation". Even though medium started to increase after 12 months.

What we really don't know is, do we need something like 1-2 times a year to maintain growth, or can stay at the one dose for 1-2 years with medium dose. SHiseido should soon have 2 year data after the we have access to which is from 2018 if i remember right where they stated to do a two year evaluation after that study.

Tsuji could do many things, but we have seen many brilliant results in mice and what not that didn't translate well into humans, and that is what Tsuji still need to prove. Do they have the knowledge and resources to reach those results in humans or not?
No matter what, Tsuji is far away in the horizon, even if they got started next month, they still have the whole cell multiplication process and so on, and make sure that doesn't end up with cancer cells and so on which there will be a high risk of when doing cell replication in big scale. And we haven't heard anything about optimization in how to Tsuji avoid that hurdle within cell multiplication for hair cells.
 

That Guy

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Tsuji could do many things, but we have seen many brilliant results in mice and what not that didn't translate well into humans, and that is what Tsuji still need to prove. Do they have the knowledge and resources to reach those results in humans or not?
No matter what, Tsuji is far away in the horizon, even if they got started next month, they still have the whole cell multiplication process and so on, and make sure that doesn't end up with cancer cells and so on which there will be a high risk of when doing cell replication in big scale. And we haven't heard anything about optimization in how to Tsuji avoid that hurdle within cell multiplication for hair cells.

They have cleared all the hurdles you are talking about
 

HairSuit

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Quite the contrary. I understand that most people aren't going to be interested in even trying it like I am, and most people can't afford it like I can. It's going to be at least $900 every six months, and the plane ticket and hotel will triple that. By the time it became available in the west we would have hair multiplication as long as Tsuji's work comes through, plus we have sideless maintenance with Breezula. You're overestimating people's fear of pills. Americans LOVE their pills. They don't care about potential sides because it's so convenient. Personally I'd prefer not to take pills. I don't even take Tylenol or cold medicine, but for hair I will take a pill.
You’re right. Pills are so much easier.... that said, we are leaving out the fact that (putting aside finasteride’s side effect profile) finasteride is not a guarantee for maintenance. Works great for some. Not at all for others, and in those for whom it does work, many times it loses effectiveness over the long haul. I think IF (and It’s a big assumption) Shiseido works like we’d all hoped, but for a shorter duration, I think in time plenty of people would have no problem getting the treatment done. Also, in time, trips to Japan will not be needed as the treatment spreads overseas. Getting needles in your face every three months for wrinkles, sucks. And yet, I don’t know many women that don’t do it. Hell I know plenty of men who do. I think if word were out there that there was a side less maintenance option, folks would jump on board. Again, I’m assuming things working out well..... which they often don’t.
 

JonnyGo

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What is this a joke? This was supposed to be the guy that was gonna save us all? Pathetic.
I’m outta here, spent way too much time on this forum hoping for an alternative to fina. The harsh truth though is that finasteride in the only thing that can at least halt/slow down male pattern baldness. Nothing else works. Good luck to you all!
Jonny
 
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