Setipiprant log

[resu]

When people gets it everyone will know, it needs to be tested first.

 

[Superbee3]

Results?

Has anyone had positive results from using Setipiprant or is it still too soon?

Thanks!

 

[charlie76761]

Hi i'm thinking of getting in on a Seti GB, but something baffles - there have been 8 clinical trials with over 1000 patients and then with 211 using 1000mg (see link below), how come it wasnt noticed or reported that Seti caused any positive influence to hair loss as as a side-effect from these trials? Admittedly, of the 211 only a say, 10% - 20% will have Androgenetic Alopecia, but still, that's 21 to 42 patients.

I would have thought it would have been spotted (like finasteride when initially only used for prostate cancer, or minoxidil etc) and jumped on by pharma from the headlines rather than Cotsarelis's unrelated research that PGD2 inhibition should limit hair loss and then Seti being identified as an strong inhibitor and thus should work leading to a trials etc

Thoughts?

http://files.shareholder.com/downlo...6-9D97-631C0F6B7C97/KYTH-105_setipiprant_.pdf

 

[LawOfThelema]

Hi i'm thinking of getting in on a Seti GB, but something baffles - there have been 8 clinical trials with over 1000 patients and then with 211 using 1000mg (see link below), how come it wasnt noticed or reported that Seti caused any positive influence to hair loss as as a side-effect from these trials? Admittedly, of the 211 only a say, 10% - 20% will have Androgenetic Alopecia, but still, that's 21 to 42 patients.

I would have thought it would have been spotted (like finasteride when initially only used for prostate cancer, or minoxidil etc) and jumped on by pharma from the headlines rather than Cotsarelis's unrelated research that PGD2 inhibition should limit hair loss and then Seti being identified as an strong inhibitor and thus should work leading to a trials etc

Thoughts?

http://files.shareholder.com/downlo...6-9D97-631C0F6B7C97/KYTH-105_setipiprant_.pdf

your thought is misguided here.

even the best treatment wont regrow a substantial cosmetically observable amount of hair. and they arent looking for it anyhow so they are not going to spot it.

 

[phil13]

PM me if interested in getting in on group buy for seti. cheapest price available for a large quantity. get in on this ****.

Hi I can't pm you how do I contact you about purchasing this stuff?

 

[julien1200]

Any news on group buy ?
and results ?

 

[shutterlad]

Hey, where are people getting setipiprant, any update on this?

 

[Nadia1972]

What are the news?

 

[buckthorn]

bump

I know this is an old, outdated thread, but just wanted to add -

I will be taking 500mg of seti orally every day.

finasteride, dutasteride AND RU did not work for me, at all. In fact they caused drastic dermatitis and increased my hair loss to about 200-300 hairs per day.

I have been using minoxidil for 5 years.

I have been using seti @ 250mg/day for about 1.5 months now and my new regimen will consist entirely of -

500mg seti / day, continuation of minoxidil and continuation of dermarolling (1.5mm)

I will update in a couple months. I think, for people who failed with finasteride, that attacking the PGD2 angle in itself may be useful. we will see.

 

[hairblues]

bump

I know this is an old, outdated thread, but just wanted to add -

I will be taking 500mg of seti orally every day.

finasteride, dutasteride AND RU did not work for me, at all. In fact they caused drastic dermatitis and increased my hair loss to about 200-300 hairs per day.

I have been using minoxidil for 5 years.

I have been using seti @ 250mg/day for about 1.5 months now and my new regimen will consist entirely of -

500mg seti / day, continuation of minoxidil and continuation of dermarolling (1.5mm)

I will update in a couple months. I think, for people who failed with finasteride, that attacking the PGD2 angle in itself may be useful. we will see.

just curious is this effective in women?

No sides?

whats the negative about it?

 

[Gone]

I think the most severe side effect reported were gallstones, which can be extremely painful, but this was also just 1 case. If anything the side effects would be worse in men because Pgd2 plays a role in male sexual development, but it's unclear (I looked for the answer) which receptor pgd2 uses for this role. If it's PD1 and not Gpr44/crth2/PD2 then it makes sense that setipiprant would not have sexual side effects, but I haven't read enough of the literature on it.

I have been thinking about the role of pgd2 in hair loss and may post an idea on the topic soon. Thanks for doing this, Buckthorn.

 

[buckthorn]

just curious is this effective in women?

No sides?

whats the negative about it?

I think it should be effective for anyone that has Androgenetic Alopecia.

 

[Grasshüpfer]

I think it should be effective for anyone that has Androgenetic Alopecia.

Hey buck,
Are you also adding a small dose topically?

 

[ryan82]

Soon I will be starting treatment with setipiprant , although this is going to be an oral treatment I will start out using 5% topically. Depending on others feedback I may try taking it orally. Oc may possibly be stronger but this is much more cost effective allowing higher dosages used which is awesome I will update this log with my results and thoughts throughout my trial of this. using this combined with an AA I'm hopeful that better results can be achieved

Does Seti helps with Alopecia Areata?

 

[shutterlad]

@buckthorn just wondering where did you get your seti ?

 

[buckthorn]

Hey buck,
Are you also adding a small dose topically?

no, just orally. I have no time or patience to mix it every day. I respond strongly to any oral medication, while topicals irritate my scalp.

@buckthorn just wondering where did you get your seti ?

Kane

Does Seti helps with Alopecia Areata?

I would guess no. AA is an autoimmune disorder, while Androgenetic Alopecia is androgen driven.

 

[Folliman]

Kane doesn't have a good reputation, man. Did you do a third party purity test?

 

[Nadia1972]

Does Seti helps with Alopecia Areata?

Many people said that for AA you must use garlic .You can mix it with castor oil .It seems very effective.

 

[hairblues]

Does Seti helps with Alopecia Areata?

Keep tabs on Brotzu--those trials look good.

We are 'supposed' to hear more from Fidia by end of year.