Samumed sm04554. Only drug on phase 3

[wow-wow]

So it is the only drug on phase 3, and i totally forgot about this.
According to clinicaltrial, they should finish their phase 3 study on January 2021.
Anyone heard something else about it?

 

[Miao]

phase 2 results were great. i hope it will be approved fast from Fda and Ema soon. so we can have another drug to stop hairloss

 

[nick123]

Samumed will publish their Phase 3 results in march 2021

Interesting where did you find this information?

 

[BaldAndBalder]

phase 2 results were great. i hope it will be approved fast from Fda and Ema soon. so we can have another drug to stop hairloss

Were they? I don't remember them being "great"

 

[Selb]

What mechanism is samumed targeting?

 

[TurboFixer]

What mechanism is samumed targeting?

i thought they were wnt

 

[Will Be an Egg in 5 years]

Is it topical?

 

[ElToso]

What mechanism is samumed targeting?

Gsk3 inhibition

 

[HairlessGawd]

Is there any info yet on dosage per application for.. research purposes?

 

[Miao]

Is there any info yet on dosage per application for.. research purposes?

I dont think... U have found a website that sell it for rp?

 

[Seuxin]

Results was great ? I don't think so...

 

[iCloud]

There was about 10% increase in hair density.

 

[Paulito9x9]

Gsk3 inhibition

The only thing that I somewhat understand here https://www.samumed.com/medium/image/american-academy-of-dermatology-aad-washington-dc_19/view.aspx is WNT ¯\_(ツ)_/¯

 

[Gegen]

Gsk3 inhibition

Where did you seen that it acts on GSK3b ? From what I read, Samumed's drugs inhibit or activate enzymes that modulates Wnt upstream.

 

[ElToso]

Where did you seen that it acts on GSK3b ? From what I read, Samumed's drugs inhibit or activate enzymes that modulates Wnt upstream.

https://www.hairlosstalk.com/interact/threads/restoring-wnt-v-catenin-signaling-is-a-promising-therapeutic-strategy.128484/

 

[pegasus2]

Where did you seen that it acts on GSK3b ? From what I read, Samumed's drugs inhibit or activate enzymes that modulates Wnt upstream.

That's what GSK3b is

 

[baldlygoing]

There was about 10% increase in hair density.

But was that with or without needling?

 

[Zon Ama]

But was that with or without needling?

There was no needling mentioned in any of samumeds documents.

Does anybody have details about the side effects which can come with changing the wnt pathway? So far there were no side effects in the study, right?

 

[jan_miezda]

The only thing that I somewhat understand here https://www.samumed.com/medium/image/american-academy-of-dermatology-aad-washington-dc_19/view.aspx is WNT ¯\_(ツ)_/¯

GS3K is involved in WNT signaling

 

[jamesbooker1975]

Results was great ? I don't think so...

Sorry , but if a drug stop hair loss, without touching androgens, without side effects, and, even more, it give you a 10 :/: regrowth,it is a amazing drug.