Question: if this makes the top hair on our scalps immune to DHT, does that not only mean the prevention of further loss but also the reversal of miniaturization? Wouldn't the miniaturized hairs be able to go terminal in the absence of being affected by DHT?
Replicel Hair Loss Treatment Trial Is Set To Begin In Japan
- Thread starter hwezdarik
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I hope Shiseido will not charge twice and need to take two biopsies to perform the two repeat procedures needed to target all the hairs. I hope Shiseido is taking Buckler's theory into account lol.
i thought it took 5-8 weeks to culture the cells?
What would be more problematic for me would be having to have two punch biopsies to cover the two window periods.
If this were something that needed to be repeated every few years, they couldn't keep on taking two biopsies every round. The scarring would be disfiguring.
Blackber
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You're assuming that they can't do one biopsy and just store the cells for use 6 months after your initial injection.
If they see positive results as the trial progresses, I'm sure they'll start looking into a business model and releasing more details. Hopefully they'll determine that they can do one biopsy and store the cells for the return trip. I'm not sure if the cells lose them potency/signature if they're stored for too long. Time will tell, no sense worrying about the details until we hear it from the horses mouth.
I don't see multiple biopsies stopping anyone (especially those with severe hair loss) from getting this treatment.
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I think this was something I asked during my interview with them in Miami... I *think* they can do this without having to perform an additional biopsy.
Blackber
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Yea, now that you mention it I seem to remember you discussing that with them. I have to give that interview another listen when I have some free time. I know they also discussed how long it would take to culture the cells as well.
Yeah I am worried about all of this. I don't want lots of needless punch biopsies on my scalp.
I know Shiseido will require a biopsy so it's something of a shame to see they made an illustration showing tweezers(?!) and plucked hairs, giving the impression that this procedure could be completely non-invasive and scar-free.
Mate, I have a 1cm around strip scar. I don't like it, but you can hide it with a number 4 guard cut.
One or two .5cm biopsy punches are nothing. If they did it down by the nape, it would never be noticed anyway.
Blackber
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Agreed, people worried about a/multiple small biopsy in turn for possibly a full head of hair are crazy.
Hair from the nape is unstable (for most people). The permanent zone is far narrower.
Yes, one or two biopsies would be fine. But truth is nobody knows how often you'd need top ups. Can you imagine 5 or 6 biopsies being taken every decade?
It would be much better if they could harness the cells just by plucking hair (as shown in their illustration) or removing individual follicles like with fue.
Wow Solomon, you have actually seen the biopsy Shiseido are going to use? Well that's a relief. Do you know if they'll store your cells indefinitely?
Replicel have said different things about the biopsy size on different occasions, ranging from 4 to 8mm.
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It won't be a full head of hair! There might not be any regrowth at all. Replicel is focused on immunization not regrowth.
Tsuji's method is for permanent one time regrowth and for that I would GLADLY have biopsy/ies done.
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That's your opinion. Every presentation, interview, press release, web page, etc. talks about regrowth... their focus is on, and in their exact words a 'functional cure'.
Yeah I remember Lee Buckler saying that in your interview. I'm not sure where he's got this from because Replicel's trials didn't show any significant regrowth, only some claims of increased "density". I read no claims of de novo hair growth.
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