Proscar dosing frequency

[hiko]

Instead of taking 1/4th Proscar daily, would it be equally effective to take the full 5mg twice a week? Thanks.

 

[Bad]

In theory you could take 5mg every 5 days.

 

[Notcoolanymore]

How long does finasteride stay in your system? If I recall correctly, it isn't very long.

 

[minoxiDjunkie]

from wikipedia -

Half-life	Elderly: 8 hours Adults: 6 hours

if i could i would take a dose of 0.5 every 8 hours, meaning you get 1.5mg a day.
but now im on duta - monday, thursday and saturday.
duta has half life of 5weeks,

 

[zzzzz]

that's the half life for the drug. The inhibition of the enzyme lasts for days...so the 8 hour half life isn't really relevant

 

[Wolf Pack]

Every other day is fine. Even a gap of 2 days. Beyond that the DHT will rise as the enzymes regenerate albeit slowly. You have to see also what works for your male pattern baldness.

On my current dosage my hair is growing like mad, bit annoying, even my girl noticed. It's grown in 3 weeks from a cut what it normally takes at least 5 weeks or more. Need regrowth though.

 

[Spanishlad]

DHT levels start to rise again after 24hours so its best to take it everyday to keep levels consistent.

 

[xRedStaRx]

View attachment 29734 DHT levels start to rise again after 24hours so its best to take it everyday to keep levels consistent.

It doesn't rise to an appreciable level until about 3 days, this is more evident with continous doses.

 

[Spanishlad]

It doesn't rise to an appreciable level until about 3 days, this is more evident with continous doses.

What do you mean by appreciable level? Surely the lower you can consistently keep DHT the better. There may not be a big difference but there is a difference

 

[Wolf Pack]

What do you mean by appreciable level? Surely the lower you can consistently keep DHT the better. There may not be a big difference but there is a difference

It barley rises 1-2 ng/dl the following day. You can definitely skip one day if not two. It would not be enough to stimulate hair loss, DHT will be low. I am now on 1 mg EOD as no sides with 0.6 mg EOD.

Someone said my crown has thickened out, had some minor thinning. Few hairs appearing on hairline. But no major regrowth yet. Been just over 2 months. This pill is unreal.

 

[Spanishlad]

Ok I see what you are saying, when looking at the graph for 0.5mg there is barely a difference. I take 1.25mg per day so was looking at the graph of 1.5mg per day where it is more significant.

To most people this difference im sure is negligible but for someone who is not a great responder I guess it could make a difference.

 

[Wolf Pack]

Ok I see what you are saying, when looking at the graph for 0.5mg there is barely a difference. I take 1.25mg per day so was looking at the graph of 1.5mg per day where it is more significant.

To most people this difference im sure is negligible but for someone who is not a great responder I guess it could make a difference.

Doctors themselves say that although 1 mg per day was the only dose studied, it does not mean it's the only effective one. Plenty of studies have shown how potent finasteride is at suppressing DHT and how long that DHT suppression lasts. This is in pharmacology books and not random forum experience.

Yes for someone it could make a difference not to take the recommended 1 mg. But I do believe we should all take the least amount required and play with the dosage.

0.25 mg is effective but somewhat less than 1 mg. Anything from 0.5 onwards is about the same give or take a few %.

 

[xRedStaRx]

Ok I see what you are saying, when looking at the graph for 0.5mg there is barely a difference. I take 1.25mg per day so was looking at the graph of 1.5mg per day where it is more significant.

To most people this difference im sure is negligible but for someone who is not a great responder I guess it could make a difference.

Upon continuous dosing, it won't. The levels are more steady compared to a single dose. Not to mention that DHT needs at least 24 hours of binding time to have a miniturization effect on the hair follicle.

 

[Spanishlad]

Hey look, im no scientist so you guys could well be right, as someone who is not a great responder to the drug I just want to supress the maximum dht possible.

As far as I know in the studies all doses were evaluated up to at least 50mg per day and after weighing up efficacy vs sides 1mg daily was chosen as the sweet spot. I can only imagine that this decision was made by much cleverer people than me or you.

I dont think of 1mg as a large dose considering that people take 5mg daily for BPH.

I have been taking 1mg-1.25mg per day for the last 8 years without any problems so I see no reason to consider taking a smaller or less frequent dose.

 

[xRedStaRx]

Hey look im no scientist so you guys could well be right, as someone who is not a great responder to the drug I just want to supress the maximum dht possible.

In the studies all doses were evaluated up to 50mg per day and after weighing up efficacy vs sides 1mg was chosen as the sweet spot.

I dont see 1mg as a large dose considering that people take 5mg daily for BPH.

I have been taking 1mg-1.25mg per day for the last 8 years without any problems so I see no reason to consider taking a smaller or less frequent dose.

Your logic is flawed, but do as you please. There is little difference between a wide range of doses and frequencies.

 

[Spanishlad]

Agreed there is little difference but there is a difference.

This is not my logic, It wasnt me that decided on 1mg per day as the sweet spot and I dont pretend to know more than the people paid to evaluate this drug.