I had succes with finasteride
I had succes with finasteride-dutasteride Kombi
i had begun under finasteride with minoxidil my succes from finasteride Went down the stream
I stop minoxidil (11Month) a half Year later my Hairs very good
I take dutasteride to finasteride my Hair get better and better
than comes the New minoxidil Foam i put on, my Hairs rapidly Downhill (12Month Foam)
You can take 5mg dutasteride when minoxidil works bad you become no succes
minoxidil can IGF-1 Insulin Inhibit IGF1 is good for Good Hairs!
Next worse thing
Minoxidil increases 17?-hydroxysteroid dehydrogenase and 5?-reductase activity of cultured human dermal papilla cells from balding scalp
Toshihiro Satoa, *, Taketsugu Tadokorob, Tadashige Sonodaa, Yuji Asadaa, Satoshi Itamib and Susumu Takayasua
a Department of Dermatology, Oita Medical University, Hasama-machi, Oita 879-5593, Japan
b Department of Dermatology, Osaka University Medical School, Osaka, Japan
16 February 1999.
Abstract
Minoxidil is known to induce hair growthnext term in male pattern baldness, for which development androgen plays a central role. We studied the effect of minoxidil on testosterone metabolism by cultured dermal papilla cells from balding or nonbalding scalp and dermal fibroblasts. In all three groups, 17?-hydroxysteroid dehydrogenase activity was much higher than 5?-reductase activity. Minoxidil increased 17?-hydroxysteroid dehydrogenase activity by nearly 40% (P<0.001) in dermal papilla cells of balding scalp, whereas the effect was less marked in dermal papilla cells from nonbalding scalp and dermal fibroblasts. 5?-Reductase activity was also slightly increased by minoxidil in dermal papilla cells from balding scalp. Again, the effect on 5?-reductase activity was insignificant in the other two groups of cells. Whether such modification of testosterone metabolism in dermal papilla cells of balding scalp by minoxidil is related to its therapeutic effect remains unknown.