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New Study: Topical Cetirizine For Androgenetic Alopecia Shows Promise

Discussion in 'New Research, Studies, and Technologies' started by dr75, Jun 17, 2017.

  1. dr75

    dr75 Established Member My Regimen

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    https://www.ncbi.nlm.nih.gov/pubmed/28604133

    I read the whole article and before after pics look convincing. I am thinking of preparing a cetirizine solution and use it nightly. Anyone here tried this before? I still havent decided what to use as vehicle. Cetirizine is highly soluble in water. I am looking for input. Thanks.
     
  2. MomoGee

    MomoGee Experienced Member My Regimen

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    Can you post the pictures as a comment? I don't have access to the full article.
     
  3. Grasshüpfer

    Grasshüpfer Experienced Member My Regimen

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    Try sci-hub.cc
     
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  4. ManinBlack

    ManinBlack Experienced Member My Regimen

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    I take the pill for allergies. Maybe it helps. It's an antihistamine, maybe it works similar to Keto by reducing irritation or inflammation in the scalp
     
    #4 ManinBlack, Jun 17, 2017
    Last edited: Jun 17, 2017
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  5. MomoGee

    MomoGee Experienced Member My Regimen

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    Thanks that worked!
    If anyone else is having trouble I've uploaded the study.
     

    Attached Files:

  6. Pasbrillantebrunette

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    Thanks! Pics are quite good!
    I take it for allergies... Any idea about the vehicule??
     
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  7. thejuiceman

    thejuiceman Established Member My Regimen

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    It is adequately soluble in ethanol but best soluble in water. I'm planning on doing before and after pics with a 1% ethanol solution but the problem with buying cetirizine is that is has a bunch of inactive ingredients. Idk if a simple coffee filter would work and if it would filter out the cetirizine. Perhaps someone here might have a better idea?
     
  8. WMQ

    WMQ Experienced Member My Regimen

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    already trialed on the German forums ages ago and there is even one thread here as well

    it's worthless. If you want to cover the inflammation angle go check the pgd2 theory maybe
     
  9. thejuiceman

    thejuiceman Established Member My Regimen

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    After reading from various old threads this is what I gathered: One user claiming goods results(Chromeo), others saying they might try it, confusion about proper vehicle and amount of cetirizine, someone saying wait till setipiprant, and a few "I tried it for a few weeks and got no results". My point being those threads are hardly conclusive that it doesn't work.
     
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  10. champpy

    champpy Experienced Member

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    From the study:

    The aim of our report was to evaluate the efficacy and tolerability of a galenic lotion
    composed of cetirizine 1%, 16% cyclo-silicone-pentamer, 96°C of ethyl alcohol

    applied once a day on the scalp.

    Not sure what the cyclosilicone pentamer is used for.
    If i knew how to get pure cetirizine id be down for this.
     
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  11. Pasbrillantebrunette

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    I thought this was the placebo for the other group...
    Well, if we believe the numbers and pictures from this study we can not conclude it does not work.
     
  12. champpy

    champpy Experienced Member

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    It is, minus the cetirizine
     
  13. Pasbrillantebrunette

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    my thoughts too;)
     
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  14. champpy

    champpy Experienced Member

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    I also dont know what they mean by 96°C of ethyl alcohol.
    I wonder if thats supposed to be 96%?

    Any guys here with chemistry or lab experience that would have any ideas how to whip up a batch of this? Seems like just 3 ingredients. It also sounds like the final product was in a lotion form, not a liquid
     
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  15. hellouser

    hellouser Senior Member My Regimen

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    Quoting for truth.
     
  16. paleocapa89

    paleocapa89 Established Member

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    for the lazy ones :)

    upload_2017-6-18_7-59-28.png
     
  17. dr75

    dr75 Established Member My Regimen

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    I knew about cetirizine before, i read the hairloss forums and was aware of germans trialling this. Yet i have never seen a convincing evidence to try. Some of those guys were using water only whereas others using pg and ethanol.

    I believe this study is legit and the before after pics show substantial regrowth. The only problem is to prepare a lotion. Hay fever tablets are made in the form of cetirizine hydrochloride.
     
    #17 dr75, Jun 18, 2017
    Last edited: Jun 18, 2017
  18. FCKW36

    FCKW36 Experienced Member

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    Yes in Germany we tested it 2012 or so, but I'm not sure it was in a right vehicle...

    Btw. I don't understand the before/after pictures. Looks like completely random pics. No captions or something...
     
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  19. resu

    resu Senior Member

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    Read the letters, it's easy to figure out, most impressive is the E-F, those are FUE level results on the crown.
     
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  20. Min0

    Min0 Established Member My Regimen

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    an already approved drug that can end the nightmare ? please be true, i don't know why would they lie about it.
    this is more likely to help diffuse thinners with itchy scalps.
     
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