freakout said:the_dude said:I don't really see why this study proves that DHT is not the direct cause of baldness. They transplanted human hair in mice. It's very probable mice have much lower levels of DHT than humans since they are much smaller. So it would be the same as transplanting the hair on a castrate (or a pseudohermaphrodite type 2 like they say in the text) or something, of course it would grow back.
DHT is an androgen. The conclusion that "...the existence of an inhibitor factor other than androgens..."
was NOT mine. I never "brought it out of context".
The conclusion was made by a team of experts with PhDs.
If you knew exactly what 'androgenetics' (Propecia or Bryan's version) - the theory lies on the argument that Androgenetic Alopecia follicles CONVERT testesterone into DHT with the 5 alpha reductase "WITHIN the follicles".
Let me know if this is wrong.
Therefore, DHT levels in your blood stream or the mice's blood stream ARE INSIGNIFICANT.
In the mice experiment, all 28 men and 11 women were DIAGNOSED with androgenetics alopecia.
Furthermose, post pubertal castrates could not match those results which means that both testtosterone and DHT are NOT the miniaturizing agents.
A DHT 'direct' miniturizing effect on hair follicles was a massive marketing campaign of Propecia 20 years ago. That proposal suggests that you have no other option but to buy Propecia.
That conclusion that you cited was with regard to females developing baldness. And yes, i do believe there are other factors that can contribute to baldness, especially in women. Btw, it's not because people have PhDs they can't be wrong.
I don't know about testosterone being converted inside the follicles, but it could be true. But even then, i don't see how that leads to testosterone levels or DHT levels inside mice being insignificant. How do you explain then why castrates never develop baldness? They still make very small amounts of testosterone. If the level of testosterone is insignificant they should also develop baldness.