This post is Part 2 of the [original post which focused on various studies] that highlighted the contrasting microbiome populations on the scalp of Androgenetic Alopecia sufferers, versus that of healthy scalps.
**But that being the case, so what?**
The following study attempted to evaluate the capacity of Lindera strychnifolia root extract (LsR) to restore a healthy bacterial and fungal scalp microflora, in the belief that the relative micriobiome composition on a scalp can impact hair loss progression. Results below:
**Characteristics of healthy and androgenetic alopecia scalp microbiome: Effect of Lindera strychnifolia roots extract as a natural solution for its modulation**
**Results:** Test analysis of relative abundance comparing healthy and Androgenetic Alopecia subjects showed a significant increase of Cutibacterim acnes (P < 0.05) and Stenotrophomonas geniculata (P < 0.01) in Androgenetic Alopecia subjects. Androgenetic Alopecia scalp condition was also associated with a significant (P < 0.05) decrease of Staphylococcus epidermidis relative abundance.
A lower proportion of Malassezia genus in samples corresponding to Androgenetic Alopecia scalps and an increase of other bacterial genera (Wallemia, Eurotium) were also noted. At the species level, mean relative abundance of Malassezia restricta and Malassezia globosa were significantly lower (P < 0.05) in the Androgenetic Alopecia group.
Eighty-three days of treatment induced a significant decrease in the relative abundance of C. acnes (P < 0.05) and S. geniculata (P < 0.01). S. epidermidis increased significantly (P < 0.05).
At the same time, LsR treatment induced a significant increase in the proportion of M. restricta and M. globosa (P < 0.05).
[Read the Full Study]
**But that being the case, so what?**
The following study attempted to evaluate the capacity of Lindera strychnifolia root extract (LsR) to restore a healthy bacterial and fungal scalp microflora, in the belief that the relative micriobiome composition on a scalp can impact hair loss progression. Results below:
**Characteristics of healthy and androgenetic alopecia scalp microbiome: Effect of Lindera strychnifolia roots extract as a natural solution for its modulation**
**Results:** Test analysis of relative abundance comparing healthy and Androgenetic Alopecia subjects showed a significant increase of Cutibacterim acnes (P < 0.05) and Stenotrophomonas geniculata (P < 0.01) in Androgenetic Alopecia subjects. Androgenetic Alopecia scalp condition was also associated with a significant (P < 0.05) decrease of Staphylococcus epidermidis relative abundance.
A lower proportion of Malassezia genus in samples corresponding to Androgenetic Alopecia scalps and an increase of other bacterial genera (Wallemia, Eurotium) were also noted. At the species level, mean relative abundance of Malassezia restricta and Malassezia globosa were significantly lower (P < 0.05) in the Androgenetic Alopecia group.
Eighty-three days of treatment induced a significant decrease in the relative abundance of C. acnes (P < 0.05) and S. geniculata (P < 0.01). S. epidermidis increased significantly (P < 0.05).
At the same time, LsR treatment induced a significant increase in the proportion of M. restricta and M. globosa (P < 0.05).
[Read the Full Study]