Mechanism Of Androgenic Alopecia: Addressing Speculations Through Empirical Evidences

Armando Jose

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2010:

'These findings suggest that high glucose levels might evoke the calcification of VSMCs by inducing osteoblastic differentiation and intracellular calcium deposition via the BMP-2/Cbfα-1 pathway in HASMCs in vitro.'

Then, in our case, more glucose in certains scalp areas?
 

Poppyburner

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Then, in our case, more glucose in certains scalp areas?

2015:

'Several studies have suggested that vascular calcification is enhanced by hyperglycaemia but the mechanisms are poorly understood [18], [19]. Collectively, our results suggest that glucose itself stimulates cartilage formation in arteries. A major output of this report is the different evidences suggesting that glucose stimulates chondrocyte differentiation of mouse MOVAS cells and human VSMCs. This is supported by the increase of type II collagen expression and deposition of sulfated GAGs, two markers that are not shared by osteoblasts.'


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[Added: 16th of January, 2021:]
[From 2016:]

'High Blood-Sugar Levels Seen to Affect How Blood Vessels Contract
[...]
According to Dr. Rainbow, the study showed “that the amount of sugar, or glucose, in the blood changes the behaviour of blood vessels, making them contract more than normal. This could result in higher blood pressure, or could reduce the amount of blood that flows through vital organs.”'

 
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