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Considering how the lotion is produced, and the carrier function of liposomes, I could say that appliying s-equol on your skin is completely useless.Hi! A Spanish guy got s-equol (95% pure) from a Chinese lab a few days ago
Considering how the lotion is produced, and the carrier function of liposomes, I could say that appliying s-equol on your skin is completely useless.Hi! A Spanish guy got s-equol (95% pure) from a Chinese lab a few days ago
Quote from the Fidia statement from last January ''We envisage the development of the potential product candidate being completed by 2018.''
Now English is not my first language, but ''by 2018'' doesn't this imply that this can hit the market this year?
Considering how the lotion is produced, and the carrier function of liposomes, I could say that appliying s-equol on your skin is completely useless.
"Considering how the lotion is produced": Neither you, nor I, nor anyone here knows how exactly the lotion is produced. How can you "consider" this? What insight could you possibly gain from considering this?
"and the carrier function of liposomes": Liposomes can be effective vehicles for either the slow release of drug, rapid uptake by cells or targeted drug delivery. Considering the fact that Brotzu detailed non-functionalized cationic liposomes with a very small mean diameter, the goal is not slow release but rather targetted delivery to the follicle; literature details the selective uptake of liposomes by pilosebaceous units.
"appliying s-equol on your skin is completely useless": This conclusion does not follow from the previous two parts of your statement at all, sir. Liposomes are not an enigma. They are just another delivery route. As long as the drug passes into the follicle and maintains an appropriate concentration, it will perform its function. Equol is not a compound that is particularly difficult to deliver.
"Considering how the lotion is produced": Neither you, nor I, nor anyone here knows how exactly the lotion is produced. How can you "consider" this? What insight could you possibly gain from considering this?
"and the carrier function of liposomes": Liposomes can be effective vehicles for either the slow release of drug, rapid uptake by cells or targeted drug delivery. Considering the fact that Brotzu detailed non-functionalized cationic liposomes with a very small mean diameter, the goal is not slow release but rather targetted delivery to the follicle; literature details the selective uptake of liposomes by pilosebaceous units.
"appliying s-equol on your skin is completely useless": This conclusion does not follow from the previous two parts of your statement at all, sir. Liposomes are not an enigma. They are just another delivery route. As long as the drug passes into the follicle and maintains an appropriate concentration, it will perform its function. Equol is not a compound that is particularly difficult to deliver.
"Considering how the lotion is produced": Neither you, nor I, nor anyone here knows how exactly the lotion is produced. How can you "consider" this? What insight could you possibly gain from considering this?
"and the carrier function of liposomes": Liposomes can be effective vehicles for either the slow release of drug, rapid uptake by cells or targeted drug delivery. Considering the fact that Brotzu detailed non-functionalized cationic liposomes with a very small mean diameter, the goal is not slow release but rather targetted delivery to the follicle; literature details the selective uptake of liposomes by pilosebaceous units.
"appliying s-equol on your skin is completely useless": This conclusion does not follow from the previous two parts of your statement at all, sir. Liposomes are not an enigma. They are just another delivery route. As long as the drug passes into the follicle and maintains an appropriate concentration, it will perform its function. Equol is not a compound that is particularly difficult to deliver.
What's weird is that the German forum also says "by 2018" which makes it really confusing cause who the hell really knows what they mean
Hi! A Spanish guy got s-equol (95% pure) from a Chinese lab a few days ago
Yes. Bear in mind that Brotzu also claims that only DGLA or only S-equol loaded in the exact same liposomal systems are completely ineffective for hairloss. Given that they work by different mechanisms, this makes little sense. That, combined with the fact that he has yet to release any data - pictures, hair counts, scalp biopsies - anything substantially compelling, means it is perfectly reasonable to remain skeptical. As a side note, Dr. Brotzu also had a slide in one of his presentations that said that equol works by inhibiting 5AR, which is not entirely true. The man is not a saint. Would it really be unreasonable to think he is mostly right but not perfectly so?Have you ever read the interviews with Brotzu? Tell me.
What's weird is that the German forum also says "by 2018" which makes it really confusing cause who the hell really knows what they mean
this probably means 31st december 2018 at 23:59 CET
Yes. Bear in mind that Brotzu also claims that only DGLA or only S-equol loaded in the exact same liposomal systems are completely ineffective for hairloss. Given that they work by different mechanisms, this makes little sense. That, combined with the fact that he has yet to release any data - pictures, hair counts, scalp biopsies - anything substantially compelling, means it is perfectly reasonable to remain skeptical. As a side note, Dr. Brotzu also had a slide in one of his presentations that said that equol works by inhibiting 5AR, which is not entirely true. The man is not a saint. Would it really be unreasonable to think he is mostly right but not perfectly so?
I cant see 2018 happening. Even if the trial proves to be successful and finishes on time, how long will it take to scale up and market this?
Cant compare pics of the 1. guyFound these pictures on IESON. Someone with the nickname: "Crazyhorse" used a lotion (seems that this lotion contains the ingredients of brotzus lotions) -- Not easy to read because I used google translator. He was so kind to post some pictures. The before pic is from March 2017 and the after pic is from Mai 2017
What do you think about it?
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These pictures were also on the thread but from another guy who tested the lotion!
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Any thoughts?