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criteria like: clear business model, step wise objectives, adequate funding, robust research done in universities
It seems like there's people everywhere doing hair cloning now.
- Thread starter Raccooner
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any so-called 'scientists' performing initial trials on mice, and then PUBLISHING their success, should have their scalps ripped off. testing on mice doesn't mean sh*t. you can take a literal sh*t on mice and they will regrow their f*****g hair.
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I have to disagree in one sense of what you said. Too many people are not seeing the obvious in why this matters. If these mice can grow a person's human hair and well for that matter, those hair and skin strips can be harvested from the mouse and used in hair transplantation to the same individual. In other words, we likely have an option at this point. It may not be ideal, but at least it is a start. dNovo demonstrated exceptional hair growth in their mice models. I am hoping they consider my human hair grown on a mouse to transplant to human scalp idea. I wish we could get these procedures done on demand. After me explaining this, do you see the situation differently in that this is not a failure or meaningless but that we may have something that could be put to use in hair transplantation? Also, from the ethical standpoint, if one is worried about harming the mouse, they don't live too long. The hair could be harvested once the mouse has passed on. The big thing getting in the way is convincing the scientists to do this experiment I propose. Sadly, they are afraid of what could potentially go wrong and have their careers and lives upended. On the other hand, if the experiment is a success, they stand a lot to gain in reputation. Do you think my idea is one worth a try? If we could gather enough support, perhaps we could give the scientists enough encouragement and support to give it a go?
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I see the topic on this forum is still interesting to people! My things are moving forward.I think everything will work out.
This video ia from 2019?
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Yes.
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Hi Alexander,
Tell me what's moving forward on your end? Any new developments?
This post, which was made specifically for you, seems to have morphed into covering other groups of scientists working on hair loss too. Ernesto Lujan of dNovo, explained more of the process by which he generated human hair in mice, so that has been covered here. Here is the recent article covering him: Interview With Ernesto Lujan PhD Of dNovo: Reprogramming Hair Stem Cells – Follicle Thought.
Greetings,
Jeffrey
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Hi Jeffrey, you know my method is completely different. He is more natural. I get advice from specialists, and I think that a team can come together.
Also, these people had similar reasoning before.
Look at the link to the article.
www.researchgate.net
Also, these people had similar reasoning before.
Look at the link to the article.
Fig. 2. Localization of putative stem cells of the bulge region (blue)...
Download scientific diagram | Localization of putative stem cells of the bulge region (blue) and hair germ cells (red) in the mouse telogen hair follicle. from publication: Hair follicle predetermination | Recent genetic and molecular studies of hair follicle (HF) biology have provided...
www.researchgate.net
H
Senior Member
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So they have to implant the hairs off the mice like a regular transplant or they have to implant the skin strip?
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They first implant the human skin graft with induced human hair stem cells on the mice (to grow the hair), then remove the skin graft with hair once it's grown to transplant to the human. I think this is best done right after the mouse dies naturally in order for the process to be humane.
H
Senior Member
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I guess so that seems like alot of mice depending on how advanced you are and itll be the same scarring youd get with multiple fut's which is unfortunate maybe you wont be able to see though.
H
Senior Member
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Wouldnt they take it from the scalp?
Histogen is not hair cloning. Replicel/Shiseido are hair cloning. Intercytex was hair cloning. Bosley had a hair-cloning research group but they failed too. They all failed because of the inductivity problem.
It is not only inductivity problem, but also you must control stem cells how they behave inside the body. That is also very big problem.
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Can you summarize the inductivity problem?
There is no inductivity problem anymore(ability of cultured cells to maintain inductivity). This hurdle was solved years ago by Tsuji. I don't know what issues they are running into now
Even if Tsuji has solved the inductivity problem any technique he uses to solve the inductivity problem would belong to him and no other companyt or research group can use it without his permission. And we can't even be sure that Tsuji has solved the inductivity problem for his own technology yet.
They can, and they do. It's literally not a problem anymore for anyone