Discussion in 'Antiandrogens - Propecia, Dutasteride, etc.' started by cyclonite, Jan 1, 2018.
Diffuse NW5 w/ NW2 hairline.
are you saying that dutasteride isn't better at reducing DHT/scalp DHT levels? are you saying that DHT levels aren't the main if not the only way to measure those kind of hair loss medications?. I don't understand your point here. a research with 416 men who showed obvious better results with dutasteride(in every dose) than 5 mg finasteride is not less "real life" than what you might see in some forum.
with all respect to hair loss forums you can get as much as false information/impression as actual information/impression if you aren't careful enough.
Yes, dutasteride reduces more DHT. I'm also saying that if you think DHT inhibition is the sole culprit for hairloss then you are sadly mistaken, and you will be disappointed by the results should you ever start dutasteride .
For example, there is a shit ton of "studies" saying PRP increased hair density. Many on this website (and other hairloss websites) have tried it multiple times, but you know what? NOTHING. NOT A SINGLE PICTURE showing improvement. If something works, people will know it.
Am I saying dutasteride doesn't work? No. Am I saying that there is NO EVIDENCE that switching from finasteride to dutasteride will give superior, VISIBLE results? Yes.
But don't take my word for it. Be honest with yourself. Take your picture of your hair now, swap to dutasteride, and assess results after 6 months. When I first learned about this drug I thought it was a miracle too, but it just isn't, nowhere close.
Of course there is more Finasteride success stories:
it's much bigger marginal difference of DHT inhibition between adding Finasteride to no antiandrogen regime than to adding Dutasteride after Finasteride regime.
Majority ( probably 90%+ of people ) are using Finasteride as their antiandrogen drug. Duta is not even official drug for androgenic alopecia in Europe and US.
If people are not here on the forum, it probably tells more about drug working than not working IHMO.
You also have one "study", where 0.5mg/week of duta is added to Finasteride regime and the difference is huge.
you are bringing here some experimental treatment and try to say that studies have no value in comparison to impression you get from a forum.
DHT reduction is the main(if not the only) way drugs like finasteride works for hair loss, the same goes for dutasteride and similar medications.
thinking twice before you believe a research is one thing but you went too far with this attitude and completely ignore science and rely only on the impression you got from a forum.
and as you can see many people with different hair loss levels use different dosage of dutasteride(I also read a lot in forums and most dutasteride users I saw only took 0.5 mg few times a week if not less) with different other medications without knowing if this is exactly what they need so how you decided that what you see on this forum is in contradiction to the studies?.
with all due respect you have nothing but a hunch here and you talk against known studies and known scientific facts here. you even talk as if I made up a rumor about how dutasteride is more effective than finasteride while it is the opinion of many other people.
The studies show a reality more real than reality itself. I remember seeing a korean study which showed that none of the participants got worse after six months taking the drug. The majority got better than baseline.
LOL. All I can say is that how something should work and how something actually works can paint two very different pictures. There are people who have switched from finasteride to dutasteride, why don't you ask them how it worked out?
Chaps in terms of dutasteride all I can tell you is this. I used finasteride for 8 years relatively successfully with only minor thinning/recession throughout that time. In the last year the itch started and I started shedding massively all over the head and lost a lot of ground. I added dutasteride 4 times a week and bang no itch.... no shedding (very minor frontal initially). I'm only 3ish months in so obviously no regrowth but definitely a "re-stabilisation. My take is simply when it works you don't hear from those folk again and when it doesn't those folk are disproportionately vocal about it. Just my 2 cents.
You seem to twist my points. I'm fully aware dutasteride inhibits more DHT. The problem you're not looking at (or maybe don't want to look at, idk) is how much of it TRANSLATES into cosmetically superior results when switching from finasteride. I argue NONE, and there is no evidence to support that there is.
There are a solid number of people using dutasteride on here. If you don't want to try it yourself, ask them how long they'v been using it, if they used finasteride before, their norwood status, etc.
The only antiandrogen that is essentially guaranteed to give cosmetically superior results is oral spironolactone, and that comes with a whole new set of problems.
Word of mouth is useless. I want to see pictures of when you were taking the finasteride with the shedding and pictures now. Many dutasteride users I've spoken to on here argue it's not even possible to get any results in 3 months.
Nothing personal, but pictures or it didn't happen.
"no evidence"? a study on more than 400 men is no evidence? even if we ignore the important DHT reduction in the scalp and in general your claim that there is "no evidence" for dutasteride working better than finasteride is simply wrong.
and think for a second how many exactly dutasteride users you actually saw/remember on this forum, 5 users? 10 users? 20 at best probably and on those users you probably don't know much and they probably used different dosages of dutasteride or might be some users who are getting panicked from the drug not working regrowing hair after few weeks or try to count the hair they shed and decided that they are losing hair even after just a week(I personally saw someone like that in a forum).
you have very little cases and you barely know much about them and/or are too different from each other in terms of doses, the medications they use, their hair loss severity, etc .
you don't have much more than a hunch and you can't compare it to any kind of study or scientific reasoning like with the DHT levels reduction thing.
Fact is, DHT inhibition is higher on Duta. Your anecdotal evidence vs. other anecdotal evidence is a pointless debate.
My boobs are a little bigger taking 0.5 a day. No other side effects.
In terms of a result and it is to me I've stopped shedding massively... that's pretty obvious I don't need camera for that. The itch is gone ....again no camera needed. In terms of the dutasteride I do it for me so I don't take photos and never have..... I've never understood the whole photos thing because if it's working it will be cosmetically obvious to me. I ain't trying to promote or convince anyone of anything just what has been thus far "working" for me. I wish you well on your hair loss journey compadre!
May I ask how long you have been on it, and whah your dose is?
Sure....... 4 times a week and finasteride on the off days. I've been using this just short of 3 months
no sides with duta ?
None so far... very occasionally sensitive nipples.
When did you notice the improvement? You on minoxidil too?
After a month or so the itch was gone and then shortly after the shedding greatly reduced to maybe one or two hairs. I'm on minoxidil once a day too and always have been. The itch was so bad I would wake up scratching my head and loose hairs in the specific areas of the itch when I would scratch. Again when I say it's working I simply mean my hair has "re-stabilised" and you know I'll take that all day long!!!