Is topical finastride a good thing?

[londonhairlossvictim]

Everyitme I meet hair transplant specialists for consultations when i ask the questions about using finastride, they always say the pill version. A few times.i have asked them about the topical ones that mix Finastride and Minoxidil, like one I got recently from a brand called FRESHMAN here in the UK but they never agree to it and say they only advise and prescribe the oral finastride pills - why is this? why are they consistently against topical finastride and specifically the mixed one of minoxidil and finastride?

 

[DoctorHouse]

Everyitme I meet hair transplant specialists for consultations when i ask the questions about using finastride, they always say the pill version. A few times.i have asked them about the topical ones that mix Finastride and Minoxidil, like one I got recently from a brand called FRESHMAN here in the UK but they never agree to it and say they only advise and prescribe the oral finastride pills - why is this? why are they consistently against topical finastride and specifically the mixed one of minoxidil and finastride?

I guess because oral is more popular since the beginning and it's so much easier to take a pill once per day, it's seems more favorable since the person will more likely comply than topical.

 

[user394587]

When the FDA approves a medication, the way the medication is delivered is a part of the approval process. Currently oral finasteride is approved for Androgenetic Alopecia in men, but the topical is not. The topical is becoming more popular, especially as of late, but it is still considered an off-label medication similar to dutasteride.

Some prescribing doctors will not prescribe topical finasteride because of this. They could encounter liability issues if a patient developed problems taking a medication that was prescribed off-label. This can largely be avoided with waivers that they will have you sign, but some doctors can't be bothered with that.

The way I look at topical finasteride is that while we know it goes systemic, we don't know how much of it goes systemic or how varying carrier solutions complicate the process. It makes more sense to me for someone to use topical finasteride because in the absolute worst case scenario, all of the drug goes systemic and you have the same effect as just taking the medication orally.

 

[randolf_faust]

When the FDA approves a medication, the way the medication is delivered is a part of the approval process. Currently oral finasteride is approved for Androgenetic Alopecia in men, but the topical is not. The topical is becoming more popular, especially as of late, but it is still considered an off-label medication similar to dutasteride.

Some prescribing doctors will not prescribe topical finasteride because of this. They could encounter liability issues if a patient developed problems taking a medication that was prescribed off-label. This can largely be avoided with waivers that they will have you sign, but some doctors can't be bothered with that.

The way I look at topical finasteride is that while we know it goes systemic, we don't know how much of it goes systemic or how varying carrier solutions complicate the process. It makes more sense to me for someone to use topical finasteride because in the absolute worst case scenario, all of the drug goes systemic and you have the same effect as just taking the medication orally.

except that you would be exposed to much more finasteride in that case then

dosis or topical finasteride is much different compared to oral

 

[user394587]

except that you would be exposed to much more finasteride in that case then

dosis or topical finasteride is much different compared to oral

That depends on how it's compounded, if you know that in one application you're getting 1 mg of finasteride, then this is what you've been exposed to if all of it goes systemic.

I have seen some ridiculous numbers in compounded liposomal finasteride where one application is around 25 mg of finasteride, which is insane to me.

 

[randolf_faust]

That depends on how it's compounded, if you know that in one application you're getting 1 mg of finasteride, then this is what you've been exposed to if all of it goes systemic.

I have seen some ridiculous numbers in compounded liposomal finasteride where one application is around 25 mg of finasteride, which is insane to me.

all these studies on topical finasteride used more then 1mg

a topical 0.25% finasteride solution would contain 2.5mg finasteride per 1 ml

 

[Thinning Sucks]

I just throw a couple 5mg in my minoxidil and call it a day...along with 1.25mg oral daily.

 

[MR sinister]

all these studies on topical finasteride used more then 1mg

a topical 0.25% finasteride solution would contain 2.5mg finasteride per 1 ml

Is this definitely the correct conversion? How do you know that? Genuinely interested as I don’t know. I’ve never been able to find a reliable conversion amount. I read different things all the time. If that is the case, then most topical fins are quite strong. I see a lot over 0.25%. The freshman example above is 0.05% I believe so that would be around 0.6mg finasteride per 1ml approx. Is that right?

 

[Janks16]

I used finasteride for 25+ years. It didn't give me more hair, but it helped me keep my hair. I would buy finasteride and cut it into quarters, but after time I noticed that fina was feminizing me by removing hair on my arms, chest, legs, though it didn't remove my beard. I'm glad that I got off it, but I'm still going to try the topical finasteride. If I see that I'm getting systemic issues, I'll get off it forever.

Primarily I'm needling and then adding minoxidil after I've needled. I haven't had any burning sensation by using in this manner.

 

[jazz1]

I am from london and order my Topical Finasteride mixture from America i have done for years, see below the compound pharmacy I use. Topical Finasteride does work but better combined with minoxidil.

https://www.hairlosstalk.com/interact/threads/topical-minoxidil-finasteride-mixture-check-here.126633/

 

[randolf_faust]

Is this definitely the correct conversion? How do you know that? Genuinely interested as I don’t know. I’ve never been able to find a reliable conversion amount. I read different things all the time. If that is the case, then most topical fins are quite strong. I see a lot over 0.25%. The freshman example above is 0.05% I believe so that would be around 0.6mg finasteride per 1ml approx. Is that right?

1mg = 0,001g


then you just put it in the formula. 0,05% is 0,5mg per 1ml i think but most topicals have a higher solution

but im not a chemist

 

[londonhairlossvictim]

Has anyone else ordered what Jazz is talking about? Or is it only him who has used this with good results?

 

[cyclonus]

I think topical finasteride is like an equation with many unknowns. We dont‘t really know how much is absorped, we dont know if it works at all topical.

 

[Thinning Sucks]

I think topical finasteride is like an equation with many unknowns. We dont‘t really know how much is absorped, we dont know if it works at all topical.

I’m doing oral and couple tabs topical in minoxidil to see if can kickstart some growth.