Is It A True Story? Something Terrible About Ru58841

[hemingway_the_mercenary]

The aim of this study was to investigate the antiandrogenic activity of a new monoester of cortexolone, cortexolone 17alpha-propionate (CAS 19608-29-8, CB-03-01). Although the compound displayed a strong local antiandrogenic activity in hamster's flank organ test, it did not exhibit antiandrogenic activity in rats after subcutaneous injection, nor did it affect gonadotropins hypersecretion when injected to parabiotic rats. As topical antiandrogen, the steroid resulted about 4 times more active than progesterone (CAS 57-83-0) and, when compared to known antiandrogen standards, it was about 3 times more potent than flutamide (CAS 13311-84-7), about 2 times more effective than finasteride (CAS 98319-26-7) and approximately as active as cyproterone acetate (CAS 427-51-0). Its pharmacological activity seemed to be primarily related to its ability to antagonistically compete at androgen receptor level; nevertheless its primary pharmacological target needs to be further investigated. Its topical activity, along with the apparent absence of systemic effects, anticipates this compound to have the potential of representing a novel and safe therapeutic approach for androgen-dependent skin disorders.

flutamide is not the active drug, they would need to compare it to hydroxyflutamide and also we'd need to see the mgs of each drug applied. This is coming directly from the company right? Seems ridiculously biased

 

[el_duterino]

 

[Dutchie]

CB is NOT easy to get

You sure??

https://www.alibaba.com/trade/search?fsb=y&IndexArea=product_en&CatId=&SearchText=CB-03-01

 

[veneno]

IF WE CAN MAKE LAB IDENTITY AND PURITY TESTS AND PUBLISH THEM IN ONE THREAD WE COULD THEN FIND A RELIBLE AND WE COULD LOWER THE CURRENT PRICE ,WE CAN SHARE OUR EXPERIENCES TO EXPOSE ANY FRAUDS OR FAKE SUPPLIERS

 

[mannyFJ]

IF WE CAN MAKE LAB IDENTITY AND PURITY TESTS AND PUBLISH THEM IN ONE THREAD WE COULD THEN FIND A RELIBLE AND WE COULD LOWER THE CURRENT PRICE

Good idea as chinese sellers can be very dodgy. Not all but been there done that

 

[hemingway_the_mercenary]

View attachment 108811

smh. thats obviously wrong, do more research.

when you reply to someone, quote them you coward

 

[FCKW36]

I'm on RU for more than 4 years (100mg every day). This is some creepy stuff

 

[FCKW36]

Man I can't use this sh*t anymore after reading the first post in this thread.

 

[FCKW36]

Current use of bicalutamide 50 mg/day was associated with a significant increase in the risk of HF (OR 3.28; 95% CI 1.31, 8.18); however, this increased risk of HF was only found in patients taking bicalutamide 50 mg/day in combination with luteinizing hormone-releasing hormone (LHRH) receptor agonists. There were no cases of hospitalized HF in patients taking bicalutamide 50 mg/day as monotherapy and there was no significant association between current use of bicalutamide 150 mg/day and the risk of hospitalized HF.

Lel