finasteride For 10 Years...the End Is Starting.

[AlmostDone]

Dutasteride has a much longer half life and blocks much more DHT than finasteride. Dutasteride also inhibits both Type 1 and Type 2 5AR, whereas finasteride blocks only type 2. Type 1 is present in most tissues in the body where 5 alpha-reductase is expressed, and is the dominant form in sebaceous glands. Type 2 is the dominant isoenzyme in genital tissues, including the prostate.

I suggest you read this publication for starters: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1472916/

Here are some effects observed for type 1 deficiency, albeit in rodents: https://diabetes.diabetesjournals.org/content/64/2/447

Here is a study in humans about insulin sensitivity changes on dutasteride: 5αR inhibition with dutasteride, but not finasteride, impairs peripheral (principally muscle) insulin sensitivity, and increases body fat and leptin: https://www.endocrine-abstracts.org/ea/0031/ea0031oc1.5

I read it and I’m still a little baffled, is there a laymen’s guide to this? Or a specialist I can speak too

 

[CrownBalding]

View attachment 133861

Dude there’s barely any recession at all wtf

 

[AlmostDone]

Dude there’s barely any recession at all wtf

I’ll get a better picture, but it’s there.
It’s mostly uneven and focused on that spot
But I’ve been on finasteride since I was 20, i want to hold the fort and cling as long as I can