Yeak i know this disease is driving you mad, known this for a while now too, and reply to this kind of sh**post is the same as pissing in the wind but anyway...
Who said PGD2 antagonist is the cure ? No one...Just a pro-inflammatory marker suggesting a strong immune response from the body located in the scalp of baldies like us, and
mast cells in particular.
This is what mast cells activation looks like during an anaphylaxis choc
View attachment 64721
Immune system, immunology, allergy and immunotherapy is still quite puzzling, ever for modern medecine, and yes
good medecine takes actually TIME, real f*****g TIME, you don't mess with the immune system like that.
Now yeah, obvisouly, some random user, with all the knowledge acquired by every means, like Swisstemples, rubbing some PGD2 bought on an obscure Chinese online store is gonna do...nothing...BUT there has been some studies on it, and on
Wound Induced Hair Follicle Neogenesis that
strongly suggest that PGD2 reaction through Gpr44 messed up the process of WIHN
Prostaglandin D2 inhibits wound-induced hair follicle neogenesis through the receptor, Gpr44
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593761/
Dr. Cots, during his research, faced the fact that this has to be inhibited in order to achieve the srongest result of WIHN, Follica protocol will have other chemicals and drugs, working in synergy, this is just a single piece of that messy complex puzzle we are talking here.
Concerning link between DHT and PGD2, no one has ever made that link or published it yet, no one can't connect dots yet....PGD2 might be elevated cause immune response to DHT is powerful, powerful enough to f*****g our hair obviously, anyway
WE DON'T KNOW YET, and by WE i mean MANKIND
Cots himself said that regimen like Finasteride will most likely have to be pursue
Allergan is testing this hypothesis as we speak, and I insist on term "hypothesis", results and tests will provide proof...or not, that's how science work btw.
Regarding
Wound Induced Hair Follicle Neogenesis, this process is known for nearly 70 f*****g years ! studied, dissected, analysed, there is litteraly tons of paper and evidences that this actually
WORKS
you want it ? you name it :
https://scholar.google.fr/scholar?hair loss=fr&as_sdt=0,5&as_vis=1&q=wound+induced+follicular+neogenesis&btnG=
Observed in mammalians like mice, swine, and even humans...
Now, Cots and his team spent many years using actual scientist methods discovering inherent mechanisms of that natural regeneration process in order to enhance it, and again it takes time, real time.
People you denigrate their works spent actually many years to achieve this kind of breakthough, and for most of them are quite underpaid.
Of course, easiest way is to run to your precious plastic surgeon, crying and hoping he will solve all your aesthetic problems, but truth is, he doesn't give a rat sh*t about you, he will ask top dollars for a two hours surgery and will be driving his porsche to his f*****g golf course with his plastic surgeons pals having a good laugh about old ladies, and millenial men now, craving for botox, boobs jobs, abs jobs, *** jobs, nose jobs whatever, and how easy it is to make good money on mankind hang-ups.
FUE is like flipping a coin, results can be natural, or you end up like a f*****g doll, spotted miles away with a fake result, and your surgeon will don't give a sh*t about that, he will just offer to make another surgery and....rollercoaster is back on
You can ask him anything, like you ever want to be a dolphin ? Swim in the ocean with your dolphins friends ? I can make it happen.