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Bicalutamide is effective in only 53% of cases of female pattern baldness. Unsurprisingly, at least half of those who tried it didn't help.
HRT may not help either, because even on HRT there will be low levels of T and DHT, and if you did not respond to Bicalutamide, you will simply continue to go bald even at the female hormonal level. Nothing can be done about it. If I have not answered Bicalutamide and am balding on the back of my head, it is quite possible that HRT will not give me anything We cannot completely get rid of androgens, and blocking the receptors does not always work. Thus, we do not have a medicine that is guaranteed to help
Spironolactone and CPA are even less effective than Bicalutamide, so the percentages are even lower in their case. Add to this the fact that Androgenetic Alopecia has more than just androgenic mechanisms. In general, we will never defeat this disease