DHEA is the first hormone, and genetics determine how much you make at a given age. How much testosterone you can make is determined by how much DHEA you have. My father has optimal testosterone levels for a 25 year old, but 10% the DHEA levels of one. He is very athletic at age 60.
Testosterone is a bulk hormone, like cortisol. It is produced by one or two organs/glands for the rest of the body. You know the effects of testosterone on your system from the blood levels.
Estrogen, DHT, and some others are non-bulk hormones. They are manufactured in individual cells by enzymes that are controlled by genetics. Their concentrations are higher in those cells than in the blood, since the amount in the blood is just what leaked out. This goes for estrogen in breast tissue, and DHT in breast tissue, and DHT in skin, hair, penis, prostate, nerves.
Testosterone makes your muscles grow. More makes them grow more. Exercise makes more testosterone. Insulin helps with bringing in protein for growth. Steroid mimic testosterone to make more growth 24-7. Muscles don't make DHT, and it either has no effect on them, or works not better than testosterone.
But most tissues don't use testosterone for androgenic signalling. They make it into DHT first. DHT is needed for nerves to stay healthy. It has uses in many organs as the androgen signaller. It is what tells your penis to grow during puberty, which is when genetics tell your penis to make more DHT. Though researchers measure the elevated blood levels that leak out during this time, the cellular concentrations are much higher. So naturally during experiments when DHT is added to the blood of adults to match adulescent levels, the penis does not grow.
DHT also causes body hair to grow, head hair to die, and sebum glands to get big and give you big pores. It also make the prostate grow a similar number of men as those who lose their hair. But we do need it in nerves, which fortunately make it with 5ar1.
As we age, our cells make diferent hormone levels, often for the worse. It is incorrect to think that we make more or less DHT or estrogen. It is better to think of what each individual tissue is making. To measure blood levels is just as erroneous as to to other diseases as to male pattern baldness.
Just as DHT evenually brings some immune attack to hair follicles, and also cause produciton of damaging chemicals, a similar effect probably occurs in other cells, like in the joints. Arthritis, lupus, asma, allergies, etc are all auto-immune conditions, often treated by steroidal drugs like prednisone. Prednisone is bad. Hormones are the bodies communicaiton tool, the maker's of which are coded for by DNA. Some are systemic, like testosterone, insulin, and cortisol. Others are cellular, like DHT and estrogen.
To fix our problems, we must think cellular, not systemic. It makes sense to bring DHEA levels to that of a 25 year old since it is needed to make the sytemic testosterone. But if women want to increase estrogen levels, or men decrease DHT levels, we must do this on a tissue by tissue basis for two reasons:
1. If you fix the blood levels to that of a 25 year old, you still don't get the tissue levels of a 25 year old. The blood levels are just what leaked out of the cells, mixed, and was disluted. Some cells need more, others less.
2. If you change stuff systemically, you help some tissues and hurt others. Dutasteride is great for hair, but could be bad for nerves and your penis. I read that men's penises get a little smaller as they age.
You can grow your penis by stretching it, just like a woman without steroids can build muscle. Dutasteride makes it harder. DHT injection in your penis would be like a guy building muscle on steroids. Just as muscles respond to testosterone, your penis and body hair respond to DHT. But your adult penis makes as much DHT as a woman makes testosterone, by analogy. and even if a study says blood DHT levels are similar, it does not matter. Only the amount made inside the penis, buy the penis, matters, so you have to apply DHT topically to the penis to get enough in there without affecting your whole body. And stretching it with a pump is kind of like working out: don't to it too much if you don't got the hormones to back it up.
Testosterone is a bulk hormone, like cortisol. It is produced by one or two organs/glands for the rest of the body. You know the effects of testosterone on your system from the blood levels.
Estrogen, DHT, and some others are non-bulk hormones. They are manufactured in individual cells by enzymes that are controlled by genetics. Their concentrations are higher in those cells than in the blood, since the amount in the blood is just what leaked out. This goes for estrogen in breast tissue, and DHT in breast tissue, and DHT in skin, hair, penis, prostate, nerves.
Testosterone makes your muscles grow. More makes them grow more. Exercise makes more testosterone. Insulin helps with bringing in protein for growth. Steroid mimic testosterone to make more growth 24-7. Muscles don't make DHT, and it either has no effect on them, or works not better than testosterone.
But most tissues don't use testosterone for androgenic signalling. They make it into DHT first. DHT is needed for nerves to stay healthy. It has uses in many organs as the androgen signaller. It is what tells your penis to grow during puberty, which is when genetics tell your penis to make more DHT. Though researchers measure the elevated blood levels that leak out during this time, the cellular concentrations are much higher. So naturally during experiments when DHT is added to the blood of adults to match adulescent levels, the penis does not grow.
DHT also causes body hair to grow, head hair to die, and sebum glands to get big and give you big pores. It also make the prostate grow a similar number of men as those who lose their hair. But we do need it in nerves, which fortunately make it with 5ar1.
As we age, our cells make diferent hormone levels, often for the worse. It is incorrect to think that we make more or less DHT or estrogen. It is better to think of what each individual tissue is making. To measure blood levels is just as erroneous as to to other diseases as to male pattern baldness.
Just as DHT evenually brings some immune attack to hair follicles, and also cause produciton of damaging chemicals, a similar effect probably occurs in other cells, like in the joints. Arthritis, lupus, asma, allergies, etc are all auto-immune conditions, often treated by steroidal drugs like prednisone. Prednisone is bad. Hormones are the bodies communicaiton tool, the maker's of which are coded for by DNA. Some are systemic, like testosterone, insulin, and cortisol. Others are cellular, like DHT and estrogen.
To fix our problems, we must think cellular, not systemic. It makes sense to bring DHEA levels to that of a 25 year old since it is needed to make the sytemic testosterone. But if women want to increase estrogen levels, or men decrease DHT levels, we must do this on a tissue by tissue basis for two reasons:
1. If you fix the blood levels to that of a 25 year old, you still don't get the tissue levels of a 25 year old. The blood levels are just what leaked out of the cells, mixed, and was disluted. Some cells need more, others less.
2. If you change stuff systemically, you help some tissues and hurt others. Dutasteride is great for hair, but could be bad for nerves and your penis. I read that men's penises get a little smaller as they age.
You can grow your penis by stretching it, just like a woman without steroids can build muscle. Dutasteride makes it harder. DHT injection in your penis would be like a guy building muscle on steroids. Just as muscles respond to testosterone, your penis and body hair respond to DHT. But your adult penis makes as much DHT as a woman makes testosterone, by analogy. and even if a study says blood DHT levels are similar, it does not matter. Only the amount made inside the penis, buy the penis, matters, so you have to apply DHT topically to the penis to get enough in there without affecting your whole body. And stretching it with a pump is kind of like working out: don't to it too much if you don't got the hormones to back it up.
