Cotsarelis And U. Penn Patent October 4, 2018

Kagaho

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FGF-9 seems to be a promising avenue for a new drug compound, coupled with a WNT agonist.

http://www.freepatentsonline.com/20180280475.pdf

...the present invention provides a method of treating hair loss in a subject comprising the step administering a composition comprising a fibroblast growth factor-9 polypeptide and a wnt polypeptide to said subject.

Probably related to the new generation drugs that Follica is developing

@InBeforeTheCure maybe you can find something interesting in this patent?
 
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Badbald

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Yeah I guess im not sure if their doing anything different here, I was reading through the article but I dont know enough about the subject to say
 

Badbald

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Yeah, also it the FGF9 will have been testes properly and I can imagine have a different/ thorough protocol for applying it.

Is there a timeline for that commercialisation?

I know follica is delayed in its 2018 release and there were rumours of the compounds being released later then the wounding device however im not sure how much of that is speculation
 

BalderBaldyBald

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What could be "new" is the use of FG9-1 and a WNT agent together after wounding.

I think those are the drug candidates Follica is testing for the second iteration of their protocol.

Very far from commercialization though.

Second iteration ? They had tried much much more compounds during those 10 years...looks more like "Some paper went out on fgf-9, let's add it to our mixture and test it ! Let's go boys !...oh sh*t, 15 terminal hairs, what now ?...wait for new papers..."
 

Kagaho

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Second iteration ? They had tried much much more compounds during those 10 years...looks more like "Some paper went out on fgf-9, let's add it to our mixture and test it ! Let's go boys !...oh sh*t, 15 terminal hairs, what now ?...wait for new papers..."

They have tried tons of stuff but are developing their own now. I think this patent could be about that.

The first iteration which is expected to start pivotal trial next year will not include new drugs, they already stated that.
 
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BetaBoy

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So they will need to get approval for 2 new drugs? That’s surely going to be atleast 10-15 years away providing they acquire massive funding.
 

Badbald

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They have tried tons of stuff but are developing their own now. I think this patent could be about that.

The first iteration which is expected to start pivotal trial next year will not include new drugs, they already stated that.

sh*t they have not even started the trial for their first therapy? I thought we were now expecting it to be released next year, if they final trial for even the device hasnt been started we may have a long wait ahead for it
 

HairCook

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So they will need to get approval for 2 new drugs? That’s surely going to be atleast 10-15 years away providing they acquire massive funding.

Nah, they gonna use whatever is available to them. At first they probably gonna use Samumed, and later WAY and CXXC5 antagonists to enhance WNT. Samumed is really not that far away to be released, I think they entered phase 3 in august?

And there are already AGF-39 and cellcurin with FGF9.

Dunno whats new about this patent.
 

BalderBaldyBald

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Jesus christ, this is gonna be a hell of a nuking cocktail, not to be drink
Did they ever stated this will have maybe some 'sides' ? What's their vehicle ?
 

tomJ

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MrV88

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They are just covering their bases in case they utilize any of these in the compound. They won't be throwing everything in.
Really ? Maybe they will utilize everything for a f*****g bombastic cocktail of every solution that will be released until 2022 and mix it together for the ultimate wounding + compound procedure that could finally lead to a real hair neogenesis?
 
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