Carnosine with microneedling! Lots of good info

CastorTroy · Feb 20, 2021

Just ran across this study so this compound basically would upregulate the growth factors in the wound healing process!!

Gegen · Feb 20, 2021

CastorTroy said:
Just ran across this study so this compound basically would upregulate the growth factors in the wound healing process!!

Very interesting ! It is so cheap, I might give it a try.

link of the original study : https://www.researchgate.net/public...ng_in_the_dbdb_mouse_model_of_type_2_diabetes

kiwi666 · Feb 21, 2021

Got a link to buy it online?

Gegen · Feb 21, 2021

kiwi666 said:
Got a link to buy it online?

Carnosine is just a dipeptide ( Alanine + Histidine ) you can find it easily. It's used as food supplement generaly.

Carnosine Powder

<p>Carnosine is a multifunctional dipeptide made up of a chemical combination of the amino acids Beta Alanine and L-Histidine.</p>

www.metabolics.com

waynakyo · Feb 21, 2021

We need this (BELOW) with wounding. Read about it quite a bit today. The science is there. The herbs are available. Kane can do it if needed I would think. De novo hair after wounding. What else do we know does that?

https://www.hairlosstalk.com/interact/threads/design-of-a-multifunctional-biomaterial-inspired-by-ancient-chinese-medicine-for-hair-regeneration-in-burned-skin.131477/

kiwi666 · Feb 22, 2021

What do you mean below? How do we do that? Oral?

waynakyo · Feb 22, 2021

No. If you read the study. They make a topical out of this. It is not bogus science. This has been used for thousands of years in China for wound healing. (everything good for wound healing is good for HFs after dermarolling deep). Now the scientists pinned down the reason it is good. And can create a more concentrated version of it. It is due to quercetine and copper. Specific mix.
They show when applied topically after wound it generates new HF, and a lot.
Maybe I am missing something, but I cannot recall there being a topical that is natural that can do such thing. I forgot.
Either way, this and PDRN after wound healing seem like the most promising things I have seen in a while.
I posted a paper on that "published studies" about the state of HF regeneration. There is also another substance rhEPO (recombinant human EPO). Should also be available because athletes used to use it.
There is nothing out there right now that is more promising than wound healing. HS regeneration through isolation of DC cells and other "cloning" are, according to that paper, very far from clinical application because the follicle does not live long. Which is why the focus by Tsuji lately was to find a way to induce a HF to go through multiples cycles. That paper I posted puts everything in perspective.

TurboFixer · Feb 24, 2021

waynakyo said:
No. If you read the study. They make a topical out of this. It is not bogus science. This has been used for thousands of years in China for wound healing. (everything good for wound healing is good for HFs after dermarolling deep). Now the scientists pinned down the reason it is good. And can create a more concentrated version of it. It is due to quercetine and copper. Specific mix.
They show when applied topically after wound it generates new HF, and a lot.
Maybe I am missing something, but I cannot recall there being a topical that is natural that can do such thing. I forgot.
Either way, this and PDRN after wound healing seem like the most promising things I have seen in a while.
I posted a paper on that "published studies" about the state of HF regeneration. There is also another substance rhEPO (recombinant human EPO). Should also be available because athletes used to use it.
There is nothing out there right now that is more promising than wound healing. HS regeneration through isolation of DC cells and other "cloning" are, according to that paper, very far from clinical application because the follicle does not live long. Which is why the focus by Tsuji lately was to find a way to induce a HF to go through multiples cycles. That paper I posted puts everything in perspective.

Great posts as usual! I always feel like you are on the brink of discovering something huge

eeyore · Feb 24, 2021

waynakyo said:
No. If you read the study. They make a topical out of this. It is not bogus science. This has been used for thousands of years in China for wound healing. (everything good for wound healing is good for HFs after dermarolling deep). Now the scientists pinned down the reason it is good. And can create a more concentrated version of it. It is due to quercetine and copper. Specific mix.
They show when applied topically after wound it generates new HF, and a lot.
Maybe I am missing something, but I cannot recall there being a topical that is natural that can do such thing. I forgot.
Either way, this and PDRN after wound healing seem like the most promising things I have seen in a while.
I posted a paper on that "published studies" about the state of HF regeneration. There is also another substance rhEPO (recombinant human EPO). Should also be available because athletes used to use it.
There is nothing out there right now that is more promising than wound healing. HS regeneration through isolation of DC cells and other "cloning" are, according to that paper, very far from clinical application because the follicle does not live long. Which is why the focus by Tsuji lately was to find a way to induce a HF to go through multiples cycles. That paper I posted puts everything in perspective.

Where can we read this paper/study?

waynakyo · Feb 24, 2021

@eeyore Here it is

https://www.hairlosstalk.com/interact/threads/design-of-a-multifunctional-biomaterial-inspired-by-ancient-chinese-medicine-for-hair-regeneration-in-burned-skin.131477/

I read the canosine thing, the numbers are not impressive franly. Quality of paper - at least the one I read on Rgate- is quite low. They even play with the size of before and after. The study that I linked up there on chinese herbs, is astounding according to people in the field, not me.

eeyore · Feb 25, 2021

waynakyo said:
@eeyore Here it is

https://www.hairlosstalk.com/interact/threads/design-of-a-multifunctional-biomaterial-inspired-by-ancient-chinese-medicine-for-hair-regeneration-in-burned-skin.131477/

I read the canosine thing, the numbers are not impressive franly. Quality of paper - at least the one I read on Rgate- is quite low. They even play with the size of before and after. The study that I linked up there on chinese herbs, is astounding according to people in the field, not me.

Thanks, though I think that's a very small snippet of a paper isn't it? For example I couldn't find where it says "HS regeneration through isolation of DC cells and other "cloning" are, according to that paper, very far from clinical application because the follicle does not live long."

bulli103 · Feb 27, 2021

oral always works better than a topical.....if it really would work, we only need keep on needling and take the carnosine pills daily (how i read 1 gr./day)......or i'm wrong ?....

yayapapaya · Feb 27, 2021

bulli103 said:
oral always works better than a topical.....if it really would work, we only need keep on needling and take the carnosine pills daily (how i read 1 gr./day)......or i'm wrong ?....

The first thing I looked up about carnosine was bio availability - and its almost non-existent. So pills do nothing, unless im missing something. Anyways, i got carnosine in liquid form from amazon. Gonna apply topically after needling once a week.

Sanchez1234 · Feb 28, 2021

What we be the dose ans vehicle?
Any side effect that might occur?

thatguydrinksbeer · Feb 28, 2021

yayapapaya said:
The first thing I looked up about carnosine was bio availability - and its almost non-existent. So pills do nothing, unless im missing something. Anyways, i got carnosine in liquid form from amazon. Gonna apply topically after needling once a week.

Which one? Also, does anyone know if l-carnosine is the same thing?

Desolation · Feb 28, 2021

yayapapaya said:
The first thing I looked up about carnosine was bio availability - and its almost non-existent. So pills do nothing, unless im missing something. Anyways, i got carnosine in liquid form from amazon. Gonna apply topically after needling once a week.

Carnosine gets broken down during digestion. The best way to raise your Carnosine levels is through Beta-alanine supplements.

When you consume carnosine by itself, your GI tract breaks it down into beta-alanine and histidine – its two amino acid constituents, and only a small amount of it is preserved at this time. Similarly, carnosine supplements typically contain less than 50% beta-alanine, and beta-alanine is a rate-limiting amino acid when making carnosine in the muscles.

Therefore, to achieve an optimal carnosine level in your body, a more effective and efficient method is to do it through beta-alanine intake.*

Capone · Feb 28, 2021

I’ve got quercetine and copper.. any point in taking them?

yayapapaya · Feb 28, 2021

thatguydrinksbeer said:
Which one? Also, does anyone know if l-carnosine is the same thing?

The one that goes under the tongue.

Xander94 · Mar 1, 2021

i told u guys i applied beta alanine after needling and got insane itch

Xander94 · Mar 1, 2021

https://www.hairlosstalk.com/interact/threads/tried-putting-beta-alanine-powder-on-my-scalp-and-resulted-in-extreme-itch.126867/#post-1932087

Carnosine with microneedling! Lots of good info

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