Androgenetic Alopecia - Nature Vs Nurture

[Mitko1]

To people who are losing hair : Are there any bald/baldning people in your family three?
I see plenty of people who lose hair and claim to not have any family history and their relatives on both sides have good hair. And I started to think is androgenetic alopecia really only due to genetics. I mean that your relatives may carry genes associated with Androgenetic Alopecia but they aren't affect and some environmental factors is what triggered the onset Androgenetic Alopecia in you like hyperinsulinemia, obesity, liver damage, stress, etc.

 

[BadInvertor]

Top people who are losing hair : Are there any bald/baldning people in your family three?
I see plenty of people who lose hair and claim to not have any family history and their relatives on both sides have good hair. And I started to think is androgenetic alopecia really only due to genetics. I mean that your relatives may carry genes associated with Androgenetic Alopecia but they aren't affect and some environmental factors is what triggered the onset Androgenetic Alopecia in you like hyperinsulinemia, obesity, liver damage, stress, etc.

Nobody knows exactly, if you search deep enough some research has been done along the way and they identified a couple of genes that they say that their responsible for it and for many other diseases but nobody knows exactly and for sure.. You can also find studies that say that people started balding when they moved to the Western diet and from the available statistics Europeans seem to be balding the most, with the Czech Republic in front of all countries with a staggering 40% of men loosing their hair from it, Germany on the second place, France on the third and so on...
What i find odd also is that people are starting to get bald sooner and sooner than any generation, from 15 year old Norwood 2 -3 to almost fully bald in their 20th's... They have an explanation for everything, that the genes passes itself faster etc but i personally think it's bullshit, it's clear for me and from my experience also that it's something that triggers it... I am loosing hair from the start of my 20th's on a very slow rate but for a couple of years accelerated and as a coincidence it accelerated when i had the most stressful period of my life and when i did not had my lifestyle under control, eating sh*t, not doing enough sports, being very stressed and sleeping very badly, the pollution and radiation in my City and in the world in general has reached a very big level and i think it's starting to be very harmful for us, humans, plants, animals etc and a lot more factors that could contribute to accelerating the process..
My opinion is that maybe it really is genetic in some way, but i really think that we inherit the follicles sensibility and that environment and stress triggers it, as soon as i started changing my life and changing cities and locations from now and then, the hair loss decreased again and entered it's pattern that it had before i had the period in my life that i think and know for sure that it accelerated it... But this is only my 2 cents, it does not mean that it's actually true or maybe at least nor for everybody !

 

[Mitko1]

Nobody knows exactly, if you search deep enough some research has been done along the way and they identified a couple of genes that they say that their responsible for it and for many other diseases but nobody knows exactly and for sure.. You can also find studies that say that people started balding when they moved to the Western diet and from the available statistics Europeans seem to be balding the most, with the Czech Republic in front of all countries with a staggering 40% of men loosing their hair from it, Germany on the second place, France on the third and so on...
What i find odd also is that people are starting to get bald sooner and sooner than any generation, from 15 year old Norwood 2 -3 to almost fully bald in their 20th's... They have an explanation for everything, that the genes passes itself faster etc but i personally think it's bullshit, it's clear for me and from my experience also that it's something that triggers it... I am loosing hair from the start of my 20th's on a very slow rate but for a couple of years accelerated and as a coincidence it accelerated when i had the most stressful period of my life and when i did not had my lifestyle under control, eating sh*t, not doing enough sports, being very stressed and sleeping very badly, the pollution and radiation in my City and in the world in general has reached a very big level and i think it's starting to be very harmful for us, humans, plants, animals etc and a lot more factors that could contribute to accelerating the process..
My opinion is that maybe it really is genetic in some way, but i really think that we inherit the follicles sensibility and that environment and stress triggers it, as soon as i started changing my life and changing cities and locations from now and then, the hair loss decreased again and entered it's pattern that it had before i had the period in my life that i think and know for sure that it accelerated it... But this is only my 2 cents, it does not mean that it's actually true or maybe at least nor for everybody !

Thank you for your response. I think European countries have most balding people due to ageing population. The more older people a country has - the more balding. Older people are more likely to be balding. You forgot to mention if there are any bald people in your family three.

 

[BadInvertor]

Thank you for your response. I think European countries have most balding people due to ageing population. The more older people a country has - the more balding. Older people are more likely to be balding.

Maybe true did not studied that well the phenomenon but i can clearly say that i can see daily at least in my country, more and more bald people and young ones, more than i ever did, and it's not like i started paying more attention after i started loosing mine also... I have a very deep sense of perception and i really notice everything, i am very perceptive of things, including others, always was... But as i said this is only my 2 cents, means nothing without sustainable data !

 

[Mitko1]

Maybe true did not studied that well the phenomenon but i can clearly say that i can see daily at least in my country, more and more bald people and young ones, more than i ever did, and it's not like i started paying more attention after i started loosing mine also... I have a very deep sense of perception and i really notice everything, i am very perceptive of things, including others, always was... But as i said this is only my 2 cents, means nothing without sustainable data !

Indeed there are many people who are balding in their early twenties.
I think that for those who have genetic predisposition for male pattern baldness, various epigenetic factors can regulate it's severity. For example with early onset of androgenetic alopecia have higher incidence of insulin resistance, and have higher body mass index on average compared to control. Have you ever seen a skinny bald man? Literally every bald men I see is either generally overweight or have high level of abdominal fat.

https://www.researchgate.net/public...y-Onset_Androgenetic_Alopecia_A_meta-analysis

Here are studies showings the influence of epigenetic factors on Androgenetic Alopecia done on twins.

https://www.jwatch.org/jd201305240000001/2013/05/24/bald-twins
.

https://www.researchgate.net/public...igenetic_differences_in_androgenetic_alopecia

I am curious what will happen to twins who live completely different lifestyles.
One is obese and eating unhealthy and the other eating very healthy and not obese.

Many people think that diet has little or no impact on male pattern baldness but this is not true. Indeed there is higher incidence of baldness in asians after they adopted western diet and I found a guy named Nicklaus Walter who stopped male pattern baldness and regrew hair only by diet.

https://www.nicklauswalter.com/blog/2018/7/18/how-i-completely-reversed-my-hair-loss-naturally
I think going on an anti-inflammatory diet that has impact on calcification and fibrosis, mediating ROS activity,reducing estrogen, and stimulating blood circulation will definitely have a great impact and might even stop male pattern baldness.

 

[Mitko1]

I believe that another reason why the incidence of baldness is increasing with age is because of deterioration of digestive tract health and difficulty of absorbing certain nutritients such as copper, iron, zinc...
I found a study that shows that 40% of androgenetic alopecia sufferers have copper deficiency 91% are deficient in alanine, 98% in leucine, 90% in histidine.
And to add the Vitamin K2 which is hard to get in our contemporary diet and fights calcification. One of the things the previously mentioned guy Nicklaus Walter added to his diet is natto which is a fermented soy that is high in vitamin K2. I didn't believe that until I saw one comment above the article where a man is saying that he noticed hair growing on a head thst has been bald for 40 years.
I found a study which says that Vitamin E may increase hair count in male pattern baldness sufferers by 42%.

There is a strong connection between baldness and calcification.
Here's a link which explains why people are going bald:
https://jamanetwork.com/journals/jama/article-abstract/256511

I found a book where it is written that temporal arteries in balding men are completely shut down.

I see often people are saying that diet has little or no impact on male pattern baldness and mention that there are people who eat crappy diet, take drugs and drink alcohol and still have a thick head of hair. That's because different people have different genetics. Some people won't become bald no matter what they do and a lot of healthy people go bald. It is because of different genetics.

 

[Michael1986]

Male pattern baldness is almost entirely genetic. Specifically, it is a polygenic condition, meaning that lots of different genes are involved rather than just one single gene. If you have male pattern baldness in your genes, there's no escaping it unless you use a treatment like finasteride, and even then it is not guaranteed that you'll be able to stop your hair loss. A person who already has the genetic predisposition can begin balding earlier or at a faster rate due to certain poor lifestyle choices such as smoking or having a bad diet. I read a study that showed this is clearly true in the case of smoking. Likewise, if you avoid smoking and if you eat healthily, sleep well, exercise well, and avoid stress then I believe you can delay the onset of hair loss as much as possible. But you will still inevitably succumb to male pattern baldness at some point. If you have male pattern baldness in your genes, ultimately the only way to have a chance to prevent the inevitable is by using proven medical hair loss treatments like finasteride.

 

[washed_up]

Have you ever seen a skinny bald man?

Can't believe this is even a question. I see them all the time. I also see morbidly obese people with great hair.

 

[whatintheworld]

There are numerous homeless men around downtown in my city that have full heads of hair. I can't imagine more unhealthy living conditions than those men have, and yet no baldness.

I believe the answer is that it is almost all completely genetic, but in some cases, environmental factors can trigger the male pattern baldness genes earlier than they should have started.

 

[Manochoice]

Indeed there are many people who are balding in their early twenties.
I think that for those who have genetic predisposition for male pattern baldness, various epigenetic factors can regulate it's severity. For example with early onset of androgenetic alopecia have higher incidence of insulin resistance, and have higher body mass index on average compared to control. Have you ever seen a skinny bald man? Literally every bald men I see is either generally overweight or have high level of abdominal fat.

https://www.researchgate.net/public...y-Onset_Androgenetic_Alopecia_A_meta-analysis

Here are studies showings the influence of epigenetic factors on Androgenetic Alopecia done on twins.

https://www.jwatch.org/jd201305240000001/2013/05/24/bald-twins
.

https://www.researchgate.net/public...igenetic_differences_in_androgenetic_alopecia

I am curious what will happen to twins who live completely different lifestyles.
One is obese and eating unhealthy and the other eating very healthy and not obese.

Many people think that diet has little or no impact on male pattern baldness but this is not true. Indeed there is higher incidence of baldness in asians after they adopted western diet and I found a guy named Nicklaus Walter who stopped male pattern baldness and regrew hair only by diet.

https://www.nicklauswalter.com/blog/2018/7/18/how-i-completely-reversed-my-hair-loss-naturally
I think going on an anti-inflammatory diet that has impact on calcification and fibrosis, mediating ROS activity,reducing estrogen, and stimulating blood circulation will definitely have a great impact and might even stop male pattern baldness.

Oh there are plenty of skinny bald and plenty if fatty with a full head of hair...

 

[badhabiz]

To people who are losing hair : Are there any bald/baldning people in your family three?
I see plenty of people who lose hair and claim to not have any family history and their relatives on both sides have good hair. And I started to think is androgenetic alopecia really only due to genetics. I mean that your relatives may carry genes associated with Androgenetic Alopecia but they aren't affect and some environmental factors is what triggered the onset Androgenetic Alopecia in you like hyperinsulinemia, obesity, liver damage, stress, etc.

Thyroid and insuline resistence are believed to have alot to do with the triggering