So the clinical research pipeline post on this site is very useful, but by now its very outdated. Histogen is almost certainly a scam. Bimatomoprost isnt ever coming to market as a hair loss drug, possibly because it isnt much more effective than minoxidil. Samumed failed to surpass finasteride results, and has since gone silent so its probably never going to come out. Aside from these failures, theres many reasons to think this is the most pivotal year in hair loss history. 1) Follica is confirmed to be in the final prepivotal stage that was promised last year. A phase 3 trial is scheduled to start in the next 6 months. They have recently secured funding. The website boasts of hair follicle neogenesis and efficacy that is 3-4x that of current treatments. 2) Shiseido is scheduled to report on its trial results, in the next 3 months. Replicel claimed a 2 year stabilisation of hair loss in all patients following 1 injection in their own phase 1 study.. I dont much trust replicel as a legitimate company but im hopeful this treatment will come to market (in Japan only) in the next 12 months. This is based on the investment Shiseido undertook on buying a cellular research lab allowing improvements on Replicels methods and results, the wording of certain emails, the breach of contract with replicel meaning Shiseido can waive the milestone royalty payments. 3) Brotzu lotion. At this point its a meme of course. But rumours are that FIDIA will report on Androgenetic Alopecia trial results in a months time in a conference. It doesnt seem to be a good chance based on comments like "reversing 5 years of hair loss" by the doctor behind the lotion. Very sensationalist and unproven claim. Here's hoping. 4) Setipiprant will almost certainly never come out, just because I dont believe PGD2 inhibition will ever beat finasteride. The Seti trial itself removed the finasteride group, most likely because the comparison would not be favourable. The good news is Fevipirant will (probably) be available in 2020 as an asthma treatment. It was supposed to be out next year but the trial got extended. Maybe to allow more time to show statistically significant efficacy? Fevi is the dutasteride to setipiprant's propecia. 5) The Tsuji team released a study at the start of this year in which the successful cloning of hair follicles was mentioned yet again. In private communications with HairLossTalk.com members, it was also claimed the inductivity problem was solved as well. First in human trials were claimed to be beginning in early 2019. Info should be coming regarding that at some point this year. 6) A korean team led by a world renowned researcher discovered a peptide that stops the negative inhibition of wnt signalling in hair loss, allowing hair regeneration. It is a patented substance that worked on scarred human skin that was grafted on mice. The findings are supposedly going to be presented at a conference in June. A mysterious reddit user claimed human studies have already begun. This seems like a lie to me, however, he reported on the study before it was even released to journals and the media, so his reliabilty has been proven once at least. Definitely the most promising at-home hair loss treatment of the bunch, but it all depends on when it will be tested on humans. By December, we could be on the brink of the first efficacious hair loss treatment in 30 years. We could be on the brink of multiple. Or... everything could fall apart. Either way, 2018 is the most pivotal year in hair loss treatment ever.