Absurd homemade topical finasteride

[Solo]

I just get my new bottle of minoxidil and I´ve made some sort of experiment, I took two proscar pills, split them in half and put them in the bottle.

I didn´t know if they will dissolve properly, and Iwas nearly sure that the blue coat was not going to dissolve at all. But after a couple of hours I checked the bottle and the pills have dissapeared!!

I mean, no suspension, no coloidal mixture, totally sollution. The mix doesn´t left a powdery sh*t in the hair, nothing, it´s just like plain minoxidil.

But I´m guessing if there´s is any sense in what I´ve done or it´s just some kind of insane baldin´ doctor useless experiment.

The point is inhibiting DHT in the scalp as you can imagine.

P.S.: I totally assume the risk of developing a pair of breasts in my scalp, but I hope they will be a hairy ones.

 

[sam-]

:ermm:

 

[Solo]

any opinions?

 

[arya]

I know there are topical finasteride. solution but I never heard anybody mixed minoxidil. With finasteride. I am just wondering, if there will be any chemical reaction between components of both med. And if there is, will it be for good or for bed. By the way, have u noticed any change of color of the minoxidil. Solution?

And its very possible that u have just discovered a break through for hair loss treatment.. Congratulation

 

[Solo]

With finasteride. I am just wondering, if there will be any chemical reaction between components of both med

Well, as I know, minoxidil molecule is quite a low energetic molecule with low reactivity. As a matter of fact, It evaporates very fast because of its low reactivity (it doesn´t link easily with surrounding molecules, so it´s prone to leave the liquid state easily). So, for minoxidil, I´m almost sure that it´s not going to react with finasteride mollecule. minoxidil will stay the same by adding finasteride.

Finasteride, I don´t know for sure. It doesn´t present any unestable group, but I don´t know for sure the behavior of finasteride in alcoholic environment, wich is the one in minoxidil solutions. I suppose that there could be an hidroxi + insaturation substitution for the =O groups that are present in both extremes of the molecule. But it also depends on temperature and concentration of alcohol. If the lactam group is altered, that is what I was talking about, the molecule would not work in tricking Testosterone. As I´ve understand the key of the affinity lies on the ring with the lactam group. If it reacts, finasteride would not work with male pattern baldness.

(hey, this is all my speculation, don´t put your faith in it)

But, I think it is not going to harm, and maybe it´s going to help preventig DHT inhibition in the scalp.

It´s quite easy to pop two pills in the bottle, that´s it all. I´ll post results.

have u noticed any change of color of the minoxidil. Solution?

No, nothing. No precipitation, total solution. It was predictable, since finasteride is a polar molecule, like the solvant. But what have surprised me is the total erradication of the blue coat. No trace of it. Well, I guess it´s its job, contain, and then dissapear.

 

[Solo]

But I forget:


Is possible to inhibit DHT in the scalp??


Is possible via finasteride mechanism??

Is the DHT in the sebum a major concern or does it just have a marginal effect on thinning??

 

[Bryan]

Finasteride, I don´t know for sure. It doesn´t present any unestable group, but I don´t know for sure the behavior of finasteride in alcoholic environment, wich is the one in minoxidil solutions.

I can think of at least a couple of topical finasteride studies in which an alcoholic (ethanol) vehicle was used, so I'm sure it's ok. I doubt those scientists would have used it, if it were a problem.

Is the DHT in the sebum a major concern or does it just have a marginal effect on thinning??

What makes you think it has ANY effect on thinning?

Bryan

 

[Solo]

No inward sebum flow???

 

[Guest]

am i wrong if i say i've read a couple of topics where people have done this with succes??

 

[Solo]

no absorption??


I´m guessing if it exists any benefit, but i´ll keep on doing this becouse is easy and costless.

am i wrong if i say i've read a couple of topics where people have done this with succes??

Really?? can you remember exactly what posts??

 

[Guest]

no sorry... i think it was someone who told about someone bla bla and so on...

 

[Bryan]

No inward sebum flow???

"Inward sebum flow"??? Huh?? :freaked: :freaked2:

Bryan

 

[hair_tomorrow]

Many forum members are split on the potential effectiveness of a topical finasteride + minoxildil solution, and whether or not it can block dht on the scalp.

However, there's at least one hairloss vendor that does sell this solution (minoxidil mixed w. finasteride) - and, at an outrageous price.

And, there's at least one member from another forum who swears that his homemade minoxidil+finasteride concoction is working very well for him.

The general recipe seems to be to add anywhere from 2 - 6 (if I were to do it , I'd use 4) proscar tabs to a 60 ml bottle of minoxidil.

I'd probably also rub off the proscar's blue dye before I put it in my minoxidil.

(I'm taking proscar internally - so I'm not going to bother w/ the topical)

 

[Solo]

"Inward sebum flow"??? Huh?? Freaked Freaked2

Ha ha ha, first of all, sorry, english is not my first language.

I mean, any kind of sebum absortion, or contact of the external sebum with the follicle, that can result in a contact between the DHT present in sebum and the follicle.

It is said (the study on the main area) that ketoconazole has some anti-DHT properties resulting in thickening of the hair shaft, and it is a topical. So, can we get something simillar with topical finasteride?

 

[arya]

It is said (the study on the main area) that ketoconazole has some anti-DHT properties resulting in thickening of the hair shaft, and it is a topical. So, can we get something simillar with topical finasteride?

There are topical solution finasteride + alcohol exists, I read an article about it some where in the web and yes its block DHT, but its not as effective as orally taken one. But some people prefer to use it, as it has minimum chance of getting any side effect

 

[Petchsky]

I would have thought it would be easier to buy some dutasteride gel caps and then pour that into your minoxidil. Just a thought...i add a MSM powder into mine and that absorbs fine, maybe just a little residue at the bottom.

 

[hair_tomorrow]

ABSTRACT
Objective: To determine, in a preliminary study, whether women with hirsutism attributable to various causes would benefit from treatment with finasteride cream.


http://www.aace.com/pub/ep/finasteride.php

 

[Thinning]

How odd, the finistride reduced their facial hair growth.

 

[Bryan]

"Inward sebum flow"??? Huh?? Freaked Freaked2

Ha ha ha, first of all, sorry, english is not my first language.

Your English is very good; it's the IDEA that I have a problem with!

I mean, any kind of sebum absortion, or contact of the external sebum with the follicle, that can result in a contact between the DHT present in sebum and the follicle.

I wouldn't worry about that. Not the least little bit.

Bryan

 

[Biostudent]

well

How odd, the finistride reduced their facial hair growth.

well, correct me if i'm wrong, but inhibiting DHT anywhere except the scalp will cause the hairs to "thin out" and eventually die, in theory. Inhibiting DHT on the scalp however, and only on the scalp, will cause the hair to grow "Fuller" and thicker (In thoery again). That's what i have gathered from my initial research on the topic.

DHT = Bad for scalp hair
DHT = Will cause body hair to grow thicker