Recent content by waynakyo

  1. waynakyo

    Hair Growth Promotion Effect of Nelumbinis Semen Extract with High Antioxidant Activity

    mice, mice, mice... This study investigated the hair regeneration promotion and hair loss prevention properties of Nelumbinis Semen (NS) extract in vitro and in vivo. The effect of NS on the proliferation and migration of human dermal papilla cells (hDPCs) was measured in vitro via CCK-8 and...
  2. waynakyo

    Researchers identify mechanism for regenerating hair follicle stem cells

    Read this https://www.nature.com/articles/d41586-021-00656-1 Guys please please can we not turn this thread into regimen update?
  3. waynakyo

    Hormonal Effects on Hair Follicles (See discussion on prolactin)

    I did not get side effects from progesterone. I used it to get over the side effects of RU, and it helped. But never used it on my scalp. After RU I never went the hormonal route. Even people who swore by RU at the end noticed side effects.
  4. waynakyo

    Maintaining Inducibility of Dermal Follicle Cells on Silk Fibroin/Sodium Alginate Scaffold for Enhanced Hair Follicle Regeneration

    straight from Wuhan Simple Summary Patients with severe skin damage need to transplant artificial skin substitutes to achieve repair, and often the repaired part cannot achieve the regeneration of accessory organs such as hair follicles. It is very important to study artificial skin...
  5. waynakyo

    Botulinum Toxin Type A for reversing hair loss

    There must be some clinics out there doing it. And they would be happy to do it. I would start there, reach out, and see what they promise. Maybe try Jeff Epstein (Florida) he is very responsive and seems on the cutting edge of things. (no conflicts of interests, just have interacted with in...
  6. waynakyo

    Botulinum Toxin Type A for reversing hair loss

    I have seen the study, there is also this one. See what they say: https://www.jwatch.org/jd201111100000001/2011/11/10/growing-hair-with-botox COMMENT The proposed mechanism for hair growth in androgenic alopecia after botulinum toxin A treatment is that paralysis of the scalp muscles enhances...
  7. waynakyo

    KY19382, a novel activator of Wnt/β-catenin signaling, promotes hair re-growth and hair follicle neogenesis

    OK I Think I would like to join this group buy. If someone knows let me know.
  8. waynakyo

    Hormonal Effects on Hair Follicles (See discussion on prolactin)

    https://www.mdpi.com/1422-0067/21/15/5342/pdf 3.2.2. Progesterone Progesterone can influence hair follicle growth through central and local action. Central action is referred to as the inhibitory effect on LH secretion, which in turn causes a decrease in ovarian theca cell stimulation...
  9. waynakyo

    KY19382, a novel activator of Wnt/β-catenin signaling, promotes hair re-growth and hair follicle neogenesis

    I have seen some people mentioning KY, which if I understand is already available from labs. Anyone experimented with it?
  10. waynakyo

    KY19382, a novel activator of Wnt/β-catenin signaling, promotes hair re-growth and hair follicle neogenesis

    Abstract Background and purpose: The promotion of hair regeneration and growth heavily depends on the activation of Wnt/β-catenin signaling in the hair follicle, including dermal papilla (DP). KY19382, one of the newly synthesized analogs of indirubin-3'-monoxime (I3O), was identified as a...
  11. waynakyo

    Hair Loss Will be Cured Within Ten Years

    I think we will sooner see baldness as a new fashion style than see a cure. Joking aside, here is an illustration of how slow the process can be. When I turned 18 (twenty years ago) I was obsessed with laser hair removal. I am as hairy as a beast. At the time, technology did exist to remove...
  12. waynakyo

    Comparative study between Minoxidil intradermal injection by derma pen versus dutasteride intradermal injection by derma pen and derma pen alone

    Nice idea but crappy execution. These guys need statisticians to help them make a rigorous study Full PDF available. Objective: To compare between minoxidil intradermal injection by derma pen versus dutasteride intradermal injection by derma pen and derma pen alone in the treatment of male...
  13. waynakyo

    Eirion patent -- company featured on HF

    https://patentimages.storage.googleapis.com/39/13/40/84586ca0f6a1fc/WO2020056160A1.pdf FROM Hair follicle thought: “Eirion’s pre-clinical product candidates ET-02 and ET-03, which contain the same small molecule, employ a brand-new mechanism of action which corrects an aging defect in the hair...
  14. waynakyo

    UK 5099 - anyone has been following this?

    This is the type of thing that Pelage is working on. But FYI these chemicals are available for those of you who run labs ;) https://cen.acs.org/pharmaceuticals/drug-delivery/Microneedle-patch-encourages-hair-regrow/97/i15 The team identified two drugs that, when applied to the skin of mice...
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