Recent content by waynakyo

I did not realize that Kintor is pursuing this and has completed phase 1 https://www.bloomberg.com/press-releases/2022-11-24/kintor-pharma-announced-completion-of-phase-i-trial-of-the-world-s-first-protac-compound-gt20029-for-topical-use

google search this freely available article to understand what PROTAC is: Recent Advances of Degradation Technologies Based on PROTAC Mechanism

if the findings are somewhat accurate this is big. Future potential in terms of improving the method is there too. PROTAC is being used for other diseases as well. Comments? Abstract Androgenetic alopecia (Androgenetic Alopecia) is a transracial and cross-gender disease worldwide with a youth-oriented...

Abstract Background: 5-alpha inhibitors are an effective treatment for androgenetic alopecia. Mesotherapy with dutasteride has been proposed as an effective method to improve hair loss and reducing systemic absorption. Objective: The main objective was to describe the safety profile of...

Anyone heard of scalp threading for Androgenetic Alopecia? i.e. experiences on this forum

Male androgenetic alopecia is a common condition and represents a major concern for patients who experience this condition. While there are different treatments to stop hair loss and improve hair density, the 5-alpha reductase inhibitors have demonstrated to be effective in improving...

https://pubmed.ncbi.nlm.nih.gov/36578576/ Androgenetic alopecia (Androgenetic Alopecia) is a non-scarring and progressive form of hair loss occurring in both men and women. Although genetic predisposition and sex steroid hormones are the main causes, many factors remain unknown, and various extrinsic factors can...

reminds me of that Israeli device marketed 10 years ago https://pubmed.ncbi.nlm.nih.gov/36582348/

Not sure how many people here on the forum tried this, maybe they can shed light https://pubmed.ncbi.nlm.nih.gov/34454613/ new one https://pubmed.ncbi.nlm.nih.gov/36525057/

and this https://www.sciencedirect.com/science/article/pii/S1742706122007309?via%3Dihub

Effective and economical cell therapy for hair regeneration Jong-Hyuk Sung 1 Affiliations expand PMID: 36370520 DOI: 10.1016/j.biopha.2022.113988 Abstract We reviewed and summarized the latest reports on the characteristics of stem cells and follicular cells that are under development for hair...

I usually post these under "published studies", but these are quite big. One of them discussed here in one thread 2. Generation and integration of hair follicle-primed spheroids in bioengineered skin constructs. Tan CT, Leo ZY, Lim CY. Biomed Mater. 2022 Oct 21;17(6). doi...

It has been down for days, and not for the first time this year. It would be sad to lose a treasure trove of data/experiences and discussions (ok not all of them for sure). I hope we will be given a heads up notice in case the site is going to go offline for good. Maybe one of us will buy it...

Any news on this? The more I read the more it seems clear that wnt/beta caretine activation is the way to go around DHT blocking as it is a downstream effect... Thoughts/updates appreciated

Costsarelis is back writing about wounds in a couple of recently published papers. He are some of the earth shattering findings after 15 years of wait: "Because a variety of factors, including environmental variables and choice of mouse strains, can affect the outcomes of a WIHN study, the...