Recent content by Squeegee 2.0

  1. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    I just started experimenting.. Give me some months.
  2. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    People on this forum need to understand that Androgenetic Alopecia is associated with prostate cancer, cardiovascular diseases, hypertension, metabolic syndrome, insulin resistance etc.. . We need to fight oxidative stress, inflammation and overreactive AR all across the damn body.
  3. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    Guys! I don't give advice anymore on hairloss treatments. It stirs way too much drama. There is a lot of haters/ b****s on this forum. Personally right now, I am micro needling every 2 weeks with blood pissing out. No Minoxidil, No finasteride. I am taking supplements. I bought individual...
  4. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    L-Glutamine is a precursor of AKG The glutamine-alpha-ketoglutarate (AKG) metabolism and its nutritional implications https://pubmed.ncbi.nlm.nih.gov/27161106/
  5. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    It rejuvenates the adipose tissue which is primordial to hair cycle: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507425/ https://www.sciencedirect.com/science/article/pii/S0022202X17330919
  6. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    It seems that AKG stimulates Stem/progenitor cells production. The loss of progenitor cells / addition of senescent cells is the main problem in Androgenetic Alopecia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026732/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293868/ But here comes AKG which is a part...
  7. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    I know! I will Johnny! I am super busy lately! It seems that the Krebs cycle is the answer to a lot of things like Autophagy, aging and health span.
  8. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    Alpha-Ketoglutarate: Physiological Functions and Applications https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703346/
  9. Squeegee 2.0

    Alpha-ketoglutarate For Adipose Tissue Rejuvenation

    In summary, through affecting histone and DNA demethylation, aKG is a critical mediator of cell differentiation and tissue homeostasis. While its level declines during aging, dietary supplementation of AKG increases intracellular aKG level, which can rejuvenate stem/progenitor cell function...
  10. Squeegee 2.0

    N-acetyl-cysteine For Treatment Of Androgenetic Alopecia In Men

    Stupid study. Nobody recovered their hairline with NAC. It's been sold everywhere for decades. Maybe just a slight improvement? I've seen some cool studies on L-Cysteine alone , precursor of Keratin and essential for Coenzyme A as well...
  11. Squeegee 2.0

    Dexpanthenol May Be A Novel Treatment For Male Androgenetic Alopecia: Analysis Of Nine Cases

    Krebs cycle intermediates regulate DNA and histone methylation: Epigenetic impact on the aging process Epigenetic changes with aging could be caused by impaired Krebs cycle function...
  12. Squeegee 2.0

    Dexpanthenol May Be A Novel Treatment For Male Androgenetic Alopecia: Analysis Of Nine Cases

    Dexpanthenol (B5) is a molecule found in the structure of the coenzyme A. It has anti-inflammatory effects including reducing the release of myeloperoxidase from granulocytes. It also has a strong antioxidative effect that increases the synthesis of glutathione, coenzyme A, and adenosine...
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