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MDA is a marker of oxidative stress.

Background Female pattern hair loss (FPHL), also known as female androgenic alopecia, is a common dermatological disorder with a multifactorial pathogenesis. Oxidative status has been implicated in the pathogenesis of several skin diseases, including FPHL. Aim This study was aimed to investigate...

You have to take EPO with Omega 3.

Membrane-associated androgen receptor (AR) potentiates its transcriptional activities by activating heat shock protein 27 (HSP27) https://www.sciencedirect.com/science/article/pii/S0021925820313260

Effects of dihydrotestosterone on rat dermal papilla cells in vitro DHT also induced the phosphorylation and nuclear translocation of heat shock protein 27 (HSP27). Moreover, DHT decreased the levels of total and nuclear β-catenin, an important regulator of hair growth and proliferation, while...

Cyanidin 3-O-arabinoside suppresses DHT-induced dermal papilla cell senescence by modulating p38-dependent ER-mitochondria contacts https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-022-00800-7 AR transcription activity was increased by about 250% with DHT, but significantly...

It seems that the general consensus is a decrease of serum PON1 enzyme activities is directly associated with systematic oxidative stress and chronic inflammation. Same conclusion on every papers/studies. example below.. I can carry on forever with so many studies. "Genetic deletion of PON1...

https://mybiohack.com/blog/paraoxonase-pon1-increase-detox-longevity https://selfhack.com/blog/about-pon1-and-natural-ways-to-increase-it/

Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077125/ Table 1 Pharmaceutical drugs found to increase PON1 activity/expression in animals or Humans Drugs PON1 increase Reference...

Androgenetic Alopecia is a PON1 gene Polymorphism? https://www.karger.com/Article/FullText/519527

The Search for Dietary Supplements to Elevate or Activate Circulating Paraoxonases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343950/ Abstract Low levels of paraoxonase 1 (PON1) have been associated with the development of several pathological conditions, whereas high levels have been shown...

Abstract Background: Androgenetic alopecia (Androgenetic Alopecia) is a common stressful form of hair loss caused by androgen excess, genetic factors, and exposure to oxidative stress (OS) with the formation of reactive oxygen species (ROS). Paraoxonase 1 (PON1) is an enzyme synthesized in the liver bound to...

Early onset androgenic alopecia as the male phenotypic equivalent of polycystic ovarian syndrome is associated in high oxidative stress. https://www.ejmanager.com/mnstemps/53/53-1618855850.pdf?t=1650158973

Evaluation of selected parameters of oxidative stress in patients with androgenetic alopecia https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330861/

Oxidative stress in androgenetic alopecia B E Prie 1, L Iosif 2, I Tivig 2, I Stoian 2, C Giurcaneanu 3 Affiliations expand PMID: 27974920 PMCID: PMC5152608 Free PMC article Abstract Rationale:Androgenetic alopecia is not considered a life threatening disease but can have serious impacts on...