Recent content by sheepish

I could be wrong, but I was under the impression that when scalp DHT is measured, most of it has come from type 1 5 alpha reductase, which plays only a small role in hair loss as it is not found in high amounts at the hair follicle, where type 2 5 alpha reductase is predominant. Surely...

Where did you get the spironolactone from? What brand is it? Thanks

This is the ref of the paper: Langlois VS, Zhang D, Cooke GM, Trudeau VL. Gen Comp Endocrinol. 2010 May 1;166(3):489-97 It references this paper - Liao, S., Liang, T., Fang, S., Shao, E., Shao, T.C., 1973. Steroid structure and androgenic activity – specificities involved in receptor binding and...

Evolution of steroid-5α-reductases and comparison of their function with 5β-reductase 2010 In marked contrast, the reproductive functions of SRD5b are largely unexplored because of the long held view that 5b-DHT does not have androgenic effects (Kokontis and Liao, 1999). Some experimental...