Recent content by el_duterino

  1. el_duterino

    Users of oral minoxidil, have you experienced any suspected effects of aging taking it?

    oral is worse than topical but depends on dosage I too k 5mg, had the skin aging effect but it went away once I stopped, so clearly it was minoxidil not just "aging" 2.5mg is the equivalent of using 5% minoxidil twice a day topical in terms of systemic absorption
  2. el_duterino

    RU58841 vs Fluridil which is better available effictive and safe

    you can buy CB powder for 500 USD for 10g I use 50mg a day so it cost 2.5 USD a day - is this the definition of very expensive ? Even if you use double, 100mg , 5 USD a day is not much, certainly not "very expensive" unless you live in a third world country. The studies used more, but if you...
  3. el_duterino

    Is it possible not to notice that I did it 3 weeks later?

    if you have enough hair on top/front you can grow it real long before the hair transplant and use it to comb over the front recipient which will look messed up for a few weeks/months
  4. el_duterino

    RU58841 vs Fluridil which is better available effictive and safe

    fluridil is much too weak to do anything, I even tried like 3 times the dosage per day just to see if it was just a dosage issue, and no, not much effect, but also no sides effects. Ru is far more effective, but you can get andro (dick..) sides and its untested so who knows what else you get...
  5. el_duterino

    Kintor's Pyrilutamide outcompetes RU-58841 (insane binding affinity)+ potential compound reveal?

    This Kintor seems to be the typical Chinese company coming strong and fast with bold and inflated claims without much of the groundwork being done to backup their claims. If they seriously think that a super strong anti androgen with a super long serum half life is going to work in dermatology...
  6. el_duterino

    Kintor's Pyrilutamide outcompetes RU-58841 (insane binding affinity)+ potential compound reveal?

    For the full details on the androgenic alopecia drug trials scroll to page 32 http://pdf.dfcfw.com/pdf/H3_AP202007241393752560_1.pdf As you can see the drug does unfortunately have a systemic life, and a pretty long one. Only using very tiny amounts of 3mg ! applied topically cannot be...
  7. el_duterino

    Kintor's Pyrilutamide outcompetes RU-58841 (insane binding affinity)+ potential compound reveal?

    The issues are lawsuits in western countries, they need to cover their backs. China is different Also, cancer drugs will get faster approval, hair loss or acne is no big priority obviously. The Darolutamide first patent was filled in 2010 as well, same time but is already fully approved and on...
  8. el_duterino

    Kintor's Pyrilutamide outcompetes RU-58841 (insane binding affinity)+ potential compound reveal?

    There is no mention of PC in the CB or RU patent. To mention both applications is just a potential hidden red flag for side effects.
  9. el_duterino

    Kintor's Pyrilutamide outcompetes RU-58841 (insane binding affinity)+ potential compound reveal?

    This is a 10 year old patent filing, not sure if moving fast is the right word here. But, since this is a Chinese company, we could imagine them moving faster than the Western ones. I find it odd that they mention prostate cancer AND androgenic alopecia in the same document, or are they...
  10. el_duterino

    Kintor new AR degrader w/o side effects

    binding affinity is about the same for those 2 ru goes systemic so it is more effective but also gives side effects and has never been fully tested in humans so there is no reasons anymore to take such risks anymore in my experience using both for extended times - RU 9 years and CB 3 years...
  11. el_duterino

    Kintor new AR degrader w/o side effects

    From the past failures of ASC-J9, fluridil, it turns out that "degrading" the AR is not an easy task in practice. You would need to use a lot of the active ingredient to achieve a sufficient level of constant degradation in order to have the cosmetic effect, via a low efficient topical...
  12. el_duterino

    regrowth by antiandrogens only , is it possible ?

    where are those unbelievable trans regrowth pics ? If the loss is recent - less than a year maybe - you may get the follicles back from the dead, with a lot of luck, but you also need minoxidil for sure. There was a guy in our office, he went from a Nw2 to a Nw4 in one year, then started finasteride and...
  13. el_duterino

    EVERYONE Will Get Finasteride Side-Effects Eventually

    If you know how to make your scalp more porous, you don't need that much per day I use 50mg, short hair, that does not cost much per day about the same as when I used real Avodart
  14. el_duterino

    EVERYONE Will Get Finasteride Side-Effects Eventually

    I consider fluridil an ineffective treatment. Its been around for maybe 20 years and I never read posts of people having success maintain hair on it, It may help a bit but its not a replacement to finasteride and is weaker than minoxidil. I even tried to use fluridil 3 times per day at 3 different times...
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