WNT10A has a functional role in Androgenetic Alopecia etiology

[IDW2BB]

http://www.ncbi.nlm.nih.gov/pubmed/23358095

The strongest association signal was obtained for rs7349332 (P=3.55 × 10(-15)) on chr2q35, which is located intronically in WNT10A. Expression studies in human hair follicle tissue suggest that WNT10A has a functional role in Androgenetic Alopecia etiology. Thus, our study provides genetic evidence supporting an involvement of WNT signaling in Androgenetic Alopecia development.

 

[Armando Jose]

http://www.readcube.com/articles/10.1038/jid.2012.407

It is a new line of investigation but male pattern baldness is a poligenetic issue.