I started using it when I began my finasteride, minoxidil regimen but have since discontinued. Not beacause I don't think it would help but I think I am going to see how finasteride and minoxidil work first and then maybe add spironolactone later. That being said I had no problems for the few weeks I was on it. I recomend using Dr. Lees 5% spironolactone. It is a breeze to apply and doesn't smell bad like some of the other formulations.